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CAS: 154-87-0
分子式: C12H19N4O7P2S·Cl
分子量: 460.76
中文名称: 
辅羧酶
辅羧辅酶
英文名称: 
Thiazolium,3-[(4-amino-2-methyl-5-pyrimidinyl)methyl]-4-methyl-5-(4,6,6-trihydroxy-3,5-dioxa-4,6-diphosphahex-1-yl)-,chloride,P,P'-dioxide
Thiazolium, 3-[(4-amino-2-methyl-5-pyrimidinyl)methyl]-4-methyl-5-(4,6,6-trihydroxy-3,5-dioxa-4,6-diphosphahex-1-yl)-, chloride, P,P'-dioxide
thiamine, trihydrogen pyrophosphate (ester)
b-neurox
berolase
biosyth
bioxylasi
bivitasi
co-bi
cocarbina
cocarboxil
cocarboxylase
coenbione
coxylase
diphosphothiamin
diphosphothiamine
farmaneurina
metabolase
nutrase
pyrolase
pyruvodehydrase
tdp (thiamin ester)
thiamine pyrophosphate
thiamine pyrophosphate chloride
thiamine pyrophosphoric ester
thiamine-pp
thiaminediphosphate
thiaminepyrophosphate
thiaminpyrophosphate
thiazolium, 3-[(4-amino-2-methyl-5-pyrimidinyl)methyl]-4-methyl-5-(4,6,6-trihyd
roxy-3,5-dioxa-4,6-diphosphahex-1-yl)-, chloride, p,p'-dioxide
tpp (coenzyme)
展开更多英文名
推荐供应商
货号品牌产品名称规格包装、参考价格详情
T729118MACKLIN硫胺素焦磷酸盐(维生素B1焦磷酸盐) 溶液1mg/mL in 50:50 Methanol:Water580元/1ml;   展开
储存:−20°C
T819547MACKLIN焦磷酸硫胺素98%88元/250mg;   205元/1g;   449元/5g;   2003元/25g;   展开
储存:-20°C
状态:NA
T793594MACKLIN焦磷酸硫胺素10mM in Water205元/1ml;   展开
储存:-20°C, 避光
状态:液体
T0183TCIThiamine Pyrophosphate Chloride>98.0%(T)590元/5G;   展开

基本信息

纯度/分析方法>98.0%(T)
分子式/分子量C12H19ClN4O7P2S = 460.76
外观与形状(20℃)固体
储存温度0-10℃
应避免的情况光,加热
Reaxys-RN3875902
PubChem物质ID87576176
SDBS (AIST Spectral DB)4986
MDL编号MFCD00038740

技术规格

AppearanceWhite to Almost white powder to crystal
Purity(HPLC)min. 95.0 area%
Purity(Neutralization titration)min. 98.0 %

相关法规

RTECS#XI7552000
394244J&KThiamine Pyrophosphate Chloride98%179元/1G;   714元/5G;   2849元/25G;   展开

基本信息

分子式C12HCl19N4O7P2S
分子量460.77
熔点240-244
MDL编码MFCD00038740
Beilstein3875902
EINECS 编号205-836-1
存储条件Freezer -20℃

安全信息

WGK3
RTECSXI7552000
TSCA
C8754Sigma-AldrichThiamine pyrophosphate≥95%348.05元/1 G;   761.7元/5 G;   3469.78元/25 G;   9461.59元/100 G;   展开

产品说明

应用

Sigma的硫胺素焦磷酸用作底物,以检测从大鼠组织分离的高尔基体片层中的酶。
硫胺焦磷酸盐已被用于:

  • 制备壳聚糖纳米粒子
  • 在高性能
  • 液相色谱(HPLC)分析中,作为维生素B1及其衍生物的标准品
  • 免疫荧光

包装

1, 5, 25, 100 g in poly bottle

生化/生理作用

硫胺焦磷酸盐(TPP)是一种转酮醇酶的辅酶,可催化5-磷酸核糖的裂解。该反应可生成D-甘油醛-3-磷酸。该反应需要加入受体醛,例如核糖-5-磷酸、甘油醛或乙醇醛。TPP能够在′受体醛′存在下使羟基丙酮酸脱羧。

基本信息

经验(实验)分子式C12H19ClN4O7P2S
分子量460.77
Beilstein3875902
EC 号205-836-1
MDL编号MFCD00038740
PubChem化学物质编号24893100
NACRESNA.54

产品性质

质量水平200
测定≥95%
形式powder
溶解性H2O: soluble 50 mg/mL, clear to very slightly hazy, colorless
储存温度−20℃
SMILES stringCC1=C(CCOP(OP(O)(O)=O)(O)=O)SC=[N+]1CC2=C(N)N=C(C)N=C2.[Cl-]
InChI1S/C12H18N4O7P2S.ClH/c1-8-11(3-4-22-25(20,21)23-24(17,18)19)26-7-16(8)6-10-5-14-9(2)15-12(10)13;/h5,7H,3-4,6H2,1-2H3,(H4-,13,14,15,17,18,19,20,21);1H
InChI keyYXVCLPJQTZXJLH-UHFFFAOYSA-N

安全信息

储存分类代码13 - Non Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
个人防护装备Eyeshields, Gloves, type N95 (US)
PHR1369SupelcoThiamine pyrophosphatePharmaceutical Secondary Standard; Certified Reference Material1904.93元/500 MG;   展开

产品说明

一般描述

Certified pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Thiamine pyrophosphate is a coenzyme of transketolase that catalyzes the cleavage of ribulose-5-phosphate; thereby forming D-glyceraldehyde-3-phosphate. This reaction requires the addition of an acceptor aldehyde such as ribose-5-phosphate, glyceraldehye or glycolaldehyde.

应用

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

分析说明

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

其他说明

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

附注

To see an example of a Certificate of Analysis for this material enter LRAA1473 in the slot below. This is an example certificate only and may not be the lot that you receive.

基本信息

经验(实验)分子式C12H19ClN4O7P2S
分子量460.77
Beilstein3875902
EC 号205-836-1
MDL编号MFCD00038740
PubChem化学物质编号329823348
NACRESNA.24

产品性质

质量水平300
等级certified reference material
pharmaceutical secondary standard
CofAcurrent certificate can be downloaded
technique(s)HPLC: suitable
gas chromatography (GC): suitable
application(s)pharmaceutical (small molecule)
格式neat
药典可追溯性traceable to USP 1656002
储存温度-10 to -25℃
SMILES stringCC1=C(CCOP(OP(O)(O)=O)(O)=O)SC=[N+]1CC2=C(N)N=C(C)N=C2.[Cl-]
InChI1S/C12H18N4O7P2S.ClH/c1-8-11(3-4-22-25(20,21)23-24(17,18)19)26-7-16(8)6-10-5-14-9(2)15-12(10)13;/h5,7H,3-4,6H2,1-2H3,(H4-,13,14,15,17,18,19,20,21);1H
InChI keyYXVCLPJQTZXJLH-UHFFFAOYSA-N

安全信息

象形图GHS07
警示用语:Warning
危险声明H317
预防措施声明P261 - P272 - P280 - P302 + P352 - P333 + P313 - P362 + P364
危险分类Skin Sens. 1
储存分类代码11 - Combustible Solids
WGKWGK 1
闪点(F)Not applicable
闪点(C)Not applicable
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