| CAS: | 1537224-27-3 | |||||
| 英文名称: |
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| 货号 | 品牌 | 产品名称 | 规格 | 包装、参考价格 | 详情 | ||||||||||||||||||||||||||||||||||||||||||||||
| SRP0341 | Sigma-Aldrich | cKit active human | recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE) | 7215.94元/10 μG; | 展开 | ||||||||||||||||||||||||||||||||||||||||||||||
产品说明 一般描述 Human Kit ( GenBank Accession No. NM_000222), amino acids 544-976 with N-terminal His-tag, MW=50 kDa, expressed in a Baculovirus infected Sf9 cell expression system. 应用 Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling. 单位定义 One unit is defined as the amount of enzyme that will phosphorylate 1 nmol of tyrosine substrate per minute at pH 7.4 and 30℃. 基本信息
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| SRP0342 | Sigma-Aldrich | cKit active human | recombinant, expressed in baculovirus infected Sf9 cells, ≥32% (SDS-PAGE) | 7278.62元/10 μG; | 展开 | ||||||||||||||||||||||||||||||||||||||||||||||
产品说明 一般描述 Human cKit (D816V) ( GenBank Accession No. NM_000222), amino acids 544-end with N-terminal His-tag, MW=50 kDa, expressed in an Baculovirus infected Sf9 cell expression system. 应用 Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling. 外形 Fomulated in 25 mM Tris-HCl, pH 8.0, 138 mM NaCl, 0.05% Tween-20, 3 mM DTT and 10% glycerol. 基本信息
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| SRP0343 | Sigma-Aldrich | cKit active human | recombinant, expressed in baculovirus infected Sf9 cells, ≥22% (SDS-PAGE) | 7278.62元/10 μG; | 展开 | ||||||||||||||||||||||||||||||||||||||||||||||
产品说明 一般描述 Human cKit (V560G) ( GenBank Accession No. NM_000222), amino acids 544-end with N-terminal His-tag, MW=50 kDa, expressed in an Baculovirus infected Sf9 cell expression system. 应用 Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling. 基本信息
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| SRP5299 | Sigma-Aldrich | c-KIT (D820E), active, GST tagged human | PRECISIO®, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution | 6468.88元/10 μG; | 展开 | ||||||||||||||||||||||||||||||||||||||||||||||
产品说明 一般描述 c-KIT is a proto-oncogene and a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor). c-KIT was first identified as the cellular homolog of the feline sarcoma viral oncogene v-kit. c-KIT together with its ligand regulates growth and activation of a variety of hemopoietic and non-hemopoietic cells. Mutations in c-KIT are associated with gastrointestinal stromal tumors, mast cell disease, acute myelogenous lukemia, and piebaldism. Recently, deregulation of the KIT receptor TK by the prevalent activation loop mutation D816V has served as a focal point in therapeutic strategies aimed at curbing neoplastic mast cell growth. 外形 Supplied in 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 10 mM glutathione, 0.1 mM EDTA, 0.25 mM DTT, 0.1 mM PMSF, 25% glycerol. 制备说明 After opening, aliquot into smaller quantities and store at -70 ℃. Avoid repeating handling and multiple freeze/thaw cycles. 法律信息 PRECISIO is a registered trademark of sigma-aldrich Co. LLC 基本信息
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| SRP5300 | Sigma-Aldrich | c-KIT (N822K), active, GST tagged human | PRECISIO®, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution | 6468.88元/10 μG; | 展开 | ||||||||||||||||||||||||||||||||||||||||||||||
产品说明 一般描述 c-KIT is a proto-oncogene and a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor). c-KIT was first identified as the cellular homolog of the feline sarcoma viral oncogene v-kit. c-KIT together with its ligand regulates growth and activation of a variety of hemopoietic and non-hemopoietic cells. Mutations in c-KIT are associated with gastrointestinal stromal tumors, mast cell disease, acute myelogenous lukemia, and piebaldism. Recently, deregulation of the KIT receptor TK by the prevalent activation loop mutation D816V has served as a focal point in therapeutic strategies aimed at curbing neoplastic mast cell growth. 外形 Supplied in 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 10 mM glutathione, 0.1 mM EDTA, 0.25 mM DTT, 0.1 mM PMSF, 25% glycerol. 制备说明 After opening, aliquot into smaller quantities and store at -70 ℃. Avoid repeating handling and multiple freeze/thaw cycles. 法律信息 PRECISIO is a registered trademark of sigma-aldrich Co. LLC 基本信息
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| SRP5310 | Sigma-Aldrich | c-KIT (Y823D), active, GST tagged human | PRECISIO®, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution | 6468.88元/10 μG; | 展开 | ||||||||||||||||||||||||||||||||||||||||||||||
产品说明 一般描述 c-KIT (Y823D) encodes the ligand-binding chain (alpha) of the gamma interferon receptor which is a heterodimer of IFNGR1 and IFNGR2. c-KIT (Y823D) is a regulator of hematopoietic stem cells during homeostasis and under conditions of infectious stress. A genetic variation in c-KIT (Y823D) is associated with susceptibility to Helicobacter pylori infection. In addition, defects in c-KIT (Y823D) are a cause of mendelian susceptibility to mycobacterial disease, also known as familial disseminated atypical mycobacterial infection. c-KIT (Y823D is also associated with the clinical outcome of HBV infection in Chinese adults. 外形 Supplied in 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 10 mM glutathione, 0.1 mM EDTA, 0.25 mM DTT, 0.1 mM PMSF, 25% glycerol. 制备说明 After opening, aliquot into smaller quantities and store at -70 ℃. Avoid repeating handling and multiple freeze/thaw cycles. 法律信息 PRECISIO is a registered trademark of sigma-aldrich Co. LLC 基本信息
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