推荐供应商

货号

品牌

产品名称

规格

包装、参考价格

T795527

MACKLIN

托吡卡胺

10mM in DMSO

408元/1ml;

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储存：-20°C

T820238

MACKLIN

托吡卡胺

≥99.0%

56元/1g; 196元/5g; 866元/25g;

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储存：2~8°C
状态：白色固体

T1470

TCI

Tropicamide

>99.0%(T)(HPLC)

880元/10G;

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基本信息

纯度/分析方法	>99.0%(T)(HPLC)
分子式/分子量	C₁₇H₂₀N₂O₂ = 284.36
外观与形状(20℃)	固体
Reaxys-RN	285563
PubChem物质ID	87577232
Merck Index (14)	9780
MDL编号	MFCD00058580

技术规格

Appearance	White to Almost white powder to crystal
Purity(HPLC)	min. 99.0 area%
Purity(Nonaqueous Titration)	min. 99.0 %
Melting point	97.0 to 100.0 ℃

物性(参考值)

熔点	98 ℃
最大吸收波长	254(HCl aq.) nm
水溶性	实际上不溶
溶解性(可溶于)	乙醇,氯仿
溶解度(极微溶)	乙醚

安全信息

图形或危害标志
信号词	警告
危险性说明	H302 : 吞咽有害。
防范说明	P501 : 将内装物/容器送到批准的废物处理厂处理。 P270 : 使用本产品时不要进食、饮水或吸烟。 P264 : 作业后彻底清洗皮肤。 P301 + P312 + P330 : 如误吞咽：如感觉不适，呼叫急救中心/医生。漱口。

相关法规

RTECS#

CY1487860

408413

J&K

Tropicamide

99%, 一种有效选择性M4拮抗剂

1188元/10G;

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基本信息

分子式	C₁₇H₂₀N₂O₂
分子量	284.35
熔点	97-100
MDL编码	MFCD00058580
Beilstein	285563
Merck	14,9780
EINECS 编号	216-140-2
存储条件	Freezer -20℃

产品描述

Tropicamide是一种抗胆碱，毒蕈碱受体M4亚型的选择性拮抗剂，IC50为8.0 nM。

靶点（IC50 & Targe）

M4 mAChR,8nM

安全信息

图形或危害标志
提示语	Warning
危险说明	H302 H312 H315 H317 H319 H332 H335
防范说明	P261 P280 P305+P351+P338
WGK	3
RTECS	CY1487860

T9778

Sigma-Aldrich

Tropicamide

solid

980.15元/100 MG; 3342.43元/1 G;

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产品说明

应用

Tropicamide has been used for studying the regulation of fragile X behavior in male mice. 1% tropicamide has also been used for dilating mice pupils.

生化/生理作用

M₄ muscarinic acetylcholine receptor antagonist.

特点和优势

This compound is a featured product for Neuroscience research. Click here to discover more featured Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.
This compound is featured on the Acetylcholine Receptors (Muscarinic) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

包装

Bottomless glass bottle. Contents are inside inserted fused cone.

制备说明

Tropicamide is soluble in 45% (w/v) aqueous 2-hydroxypropyl-beta-cyclodextrin (4.3 mg/mL) and ethanol (5.6 mg/mL).

其他说明

Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. T9778.pdf Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.

基本信息

经验(实验)分子式	C₁₇H₂₀N₂O₂
分子量	284.35
EC 号	216-140-2
MDL编号	MFCD00058580
PubChem化学物质编号	24277879
NACRES	NA.77

产品性质

质量水平	100
形式	solid
颜色	white
溶解性	45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: 4.3 mg/mL ethanol: 5.6 mg/mL H₂O: insoluble
储存温度	2-8℃
SMILES string	CCN(Cc1ccncc1)C(=O)C(CO)c2ccccc2
InChI	1S/C17H20N2O2/c1-2-19(12-14-8-10-18-11-9-14)17(21)16(13-20)15-6-4-3-5-7-15/h3-11,16,20H,2,12-13H2,1H3
InChI key	BGDKAVGWHJFAGW-UHFFFAOYSA-N
Gene Information	human ... CHRM3(1131), CHRM4(1132)

安全信息

象形图
警示用语：	Warning
危险声明	H302 + H312 + H332 - H315 - H317 - H319 - H335
预防措施声明	P261 - P280 - P301 + P312 - P302 + P352 + P312 - P304 + P340 + P312 - P305 + P351 + P338
危险分类	Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3
靶器官	Respiratory system
储存分类代码	11 - Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable

T2580000

Tropicamide

European Pharmacopoeia (EP) Reference Standard

1277.32元/ ;

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产品说明

一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

包装

Unit quantity: 50 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

注意

Please find SDS provided by EDQM here..

其他说明

Sales restrictions may apply.

基本信息

经验(实验)分子式	C₁₇H₂₀N₂O₂
分子量	284.35
MDL编号	MFCD00058580
PubChem化学物质编号	329826715
NACRES	NA.24

产品性质

等级	pharmaceutical primary standard
manufacturer/tradename	EDQM
application(s)	pharmaceutical (small molecule)
格式	neat
储存温度	2-8℃
SMILES string	CCN(Cc1ccncc1)C(=O)C(CO)c2ccccc2
InChI	1S/C17H20N2O2/c1-2-19(12-14-8-10-18-11-9-14)17(21)16(13-20)15-6-4-3-5-7-15/h3-11,16,20H,2,12-13H2,1H3
InChI key	BGDKAVGWHJFAGW-UHFFFAOYSA-N
Gene Information	human ... CHRM3(1131)

安全信息

象形图
警示用语：	Warning
危险声明	H302 + H312 + H332 - H315 - H317 - H319 - H335
预防措施声明	P261 - P280 - P301 + P312 - P302 + P352 + P312 - P304 + P340 + P312 - P305 + P351 + P338
危险分类	Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3
靶器官	Respiratory system
储存分类代码	11 - Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable

Y0001316

Tropicamide for peak identification

European Pharmacopoeia (EP) Reference Standard

1259.15元/ ;

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产品说明

一般描述

包装

Unit quantity: 10 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

注意

Please find SDS provided by EDQM here..

其他说明

Sales restrictions may apply.

基本信息

经验(实验)分子式	C₁₇H₂₀N₂O₂
分子量	284.35
MDL编号	MFCD00058580
PubChem化学物质编号	329831361
NACRES	NA.24

产品性质

等级	pharmaceutical primary standard
manufacturer/tradename	EDQM
application(s)	pharmaceutical (small molecule)
格式	neat
储存温度	2-8℃
SMILES string	CCN(Cc1ccncc1)C(=O)C(CO)c2ccccc2
InChI	1S/C17H20N2O2/c1-2-19(12-14-8-10-18-11-9-14)17(21)16(13-20)15-6-4-3-5-7-15/h3-11,16,20H,2,12-13H2,1H3
InChI key	BGDKAVGWHJFAGW-UHFFFAOYSA-N
Gene Information	human ... CHRM3(1131)

安全信息

象形图
警示用语：	Warning
危险声明	H302 + H312 + H332 - H315 - H317 - H319 - H335
预防措施声明	P261 - P280 - P301 + P312 - P302 + P352 + P312 - P304 + P340 + P312 - P305 + P351 + P338
危险分类	Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3
靶器官	Respiratory system
储存分类代码	11 - Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable

PHR3152

Supelco

Tropicamide

pharmaceutical secondary standard, certified reference material

2006.37元/500 mg;

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产品说明

一般描述

Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards

分析说明

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

其他说明

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

附注

To see an example of a Certificate of Analysis for this material enter LRAA6959(changes by product) in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

基本信息

经验(实验)分子式	C₁₇H₂₀N₂O₂
分子量	284.35
MDL编号	MFCD00058580

产品性质

等级	certified reference material pharmaceutical secondary standard
CofA	current certificate can be downloaded
包装	pkg of 500 mg
application(s)	pharmaceutical
药典可追溯性	traceable to USP 1699005
储存温度	2-8℃
SMILES string	CCN(Cc1ccncc1)C(=O)C(CO)c2ccccc2
InChI	1S/C17H20N2O2/c1-2-19(12-14-8-10-18-11-9-14)17(21)16(13-20)15-6-4-3-5-7-15/h3-11,16,20H,2,12-13H2,1H3
InChI key	BGDKAVGWHJFAGW-UHFFFAOYSA-N

安全信息

象形图
警示用语：	Warning
危险声明	H302 + H312 + H332 - H315 - H317 - H319 - H335
预防措施声明	P261 - P280 - P301 + P312 - P302 + P352 + P312 - P304 + P340 + P312 - P305 + P351 + P338
危险分类	Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3
靶器官	Respiratory system
储存分类代码	11 - Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable

1699005

USP

Tropicamide

United States Pharmacopeia (USP) Reference Standard

2633.96元/200 MG;

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产品说明

一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

分析说明

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.

其他说明

USP issued SDS can be found here.
Sales restrictions may apply.

基本信息

经验(实验)分子式	C₁₇H₂₀N₂O₂
分子量	284.35
MDL编号	MFCD00058580
PubChem化学物质编号	329751428
NACRES	NA.24

产品性质

等级	pharmaceutical primary standard
manufacturer/tradename	USP
application(s)	pharmaceutical (small molecule)
格式	neat
储存温度	2-8℃
SMILES string	CCN(Cc1ccncc1)C(=O)C(CO)c2ccccc2
InChI	1S/C17H20N2O2/c1-2-19(12-14-8-10-18-11-9-14)17(21)16(13-20)15-6-4-3-5-7-15/h3-11,16,20H,2,12-13H2,1H3
InChI key	BGDKAVGWHJFAGW-UHFFFAOYSA-N
Gene Information	human ... CHRM3(1131)

安全信息

象形图
警示用语：	Warning
危险声明	H302 + H312 + H332 - H315 - H317 - H319 - H335
预防措施声明	P261 - P280 - P301 + P312 - P302 + P352 + P312 - P304 + P340 + P312 - P305 + P351 + P338
危险分类	Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3
靶器官	Respiratory system
储存分类代码	11 - Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable

BP1047

Tropicamide

British Pharmacopoeia (BP) Reference Standard

2071.17元/50 MG;

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产品说明

一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

包装

Unit quantity: 50 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity please visit British Pharmacopoeia

其他说明

Sales restrictions may apply.

基本信息

经验(实验)分子式	C₁₇H₂₀N₂O₂
分子量	284.35
MDL编号	MFCD00058580

产品性质

等级	pharmaceutical primary standard
manufacturer/tradename	BP
格式	neat
储存温度	2-8℃
SMILES string	CCN(Cc1ccncc1)C(=O)C(CO)c2ccccc2
InChI	1S/C17H20N2O2/c1-2-19(12-14-8-10-18-11-9-14)17(21)16(13-20)15-6-4-3-5-7-15/h3-11,16,20H,2,12-13H2,1H3
InChI key	BGDKAVGWHJFAGW-UHFFFAOYSA-N
Gene Information	human ... CHRM3(1131)

安全信息

象形图
警示用语：	Warning
危险声明	H302 + H312 + H332 - H315 - H317 - H319 - H335
预防措施声明	P261 - P280 - P301 + P312 - P302 + P352 + P312 - P304 + P340 + P312 - P305 + P351 + P338
危险分类	Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3
靶器官	Respiratory system
储存分类代码	11 - Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable

175900

Fluorochem

Tropicamide

95+%

220元/250mg; 440元/1g; 1584元/5g; 2574元/10g;

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基本信息

CAS Number	1508-75-4
MDL Number	MFCD00058580
Melting Point	96-99℃

安全信息

图形或危害标志
危险性说明	H302: Harmful if swallowed. H315: Causes skin irritation. H317: May cause an allergic skin reaction. H319: Causes serious eye irritation. H332: Harmful if inhaled. H335: May cause respiratory irritation.
防范说明	P233: Keep container tightly closed. P260: Do not breathe . P261: Avoid breathing . P264: Wash hands thoroughly after handling. P270: Do not eat, drink or smoke when using this product. P271: Use only outdoors or in a well-ventilated area. P272: Contaminated work clothing should not be allowed out of the workplace. P280: Wear . P301 + P312: IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell. P302 + P352: IF ON SKIN: Wash with plenty of soap and water. P304: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.. P304 + P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing. P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P312: Call a POISON CENTER or doctor/physician if you feel unwell. P321: Specific treatment (see relevant procedures. on this label). P330: Rinse mouth. P332 + P313: If skin irritation occurs: Get medical advice/ attention. P333 + P313: If skin irritation or rash occurs: Get medical advice/attention. P337 + P313: If eye irritation persists: Get medical advice/attention. P340: Remove victim to fresh air and keep at rest in a position comfortable for breathing. P362: Take off contaminated clothing and wash before reuse. P363: Wash contaminated clothing before reuse. P403: Store in a well-ventilated place. P403 + P233: Store in a well-ventilated place. Keep container tightly closed. P405: Store locked up. P501: Dispose of contents/container to in accordance with local regulation .

HY-B0321

MCE

Tropicamide,1508-75-4,托吡卡胺_MCE(MedChemExpress)

550元/10 mM * 1 mL in DMSO; 500元/100 mg; 800元/500 mg; 1050元/1 g;

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MCE 的所有产品仅用作科学研究或药证申报，我们不为任何个人用途提供产品和服务。

Tropicamide

MCE 国际站：Tropicamide

品牌：MedChemExpress (MCE)

货号：HY-B0321

CAS 号：1508-75-4

生物活性：托吡卡胺（Ro 1-7683）是一种选择性M4毒蕈碱乙酰胆碱受体拮抗剂。作为滴眼液使用时，托吡卡胺可引起短期瞳孔散大和睫状肌麻痹。托吡卡胺可用于神经系统疾病（如癫痫）的研究[1][2][3][4]。

产品应用：1. 该化合物可作为示踪剂。2. 该化合物可作为 NMR、GC-MS 或 LC-MS 分析中的内标品，用于定量分析。

体内研究(In Vivo)：Tropicamide (2, 5 mg/kg，腹腔注射，单次给药) 改善了 Fmr1KO 小鼠的强迫行为以及学习和记忆，减少了癫痫的发生[3]。 Tropicamide (1.25–20.0 mg/kg，腹腔注射，单次给药) 在大鼠体内减少 Pilocarpine (HY-B0726A) 诱导的震颤性下颚运动[4]。 MCE尚未独立确认这些方法的准确性。仅供参考。

分子量：284.35

Formula：C17H20N2O2

性状：固体

颜色：White to off-white

中文名称：托吡卡胺

运输条件：美国大陆地区的室温；其他地区可能有所不同。

储存方式：粉末 -20°C 3年

文献引用：MCE 顾客使用本产品发表 5 篇科研文献

提供质量检测报告：Data Sheet、SDS、COA、HNMR、LCMS、产品使用指南

产品活性：Tropicamide (Ro 1-7683) 是一种选择性的 M4 毒蕈碱乙酰胆碱受体拮抗剂。Tropicamide 作为滴眼剂使用时，会产生短效散瞳 (瞳孔扩张) 和睫状肌麻痹。Tropicamide 可用于神经性疾病，如癫痫等领域的研究。

IC50 & Target：mAChR4

热门产品线：抑制剂 | 稳定性同位素标记物 | 脂质 | 糖类

MCE 抑制剂:
MedChemExpress (MCE) 提供抑制剂、激动剂、拮抗剂、激活剂、调节剂、降解剂、配体和底物等多种生物活性化合物，可用于靶点功能验证、信号转导机制研究、细胞表型分析、疾病机制研究、药效评价及活性化合物筛选。

MedChemExpress 信号通路产品覆盖细胞凋亡、自噬、细胞周期与 DNA 损伤、表观遗传、GPCR/G 蛋白、免疫与炎症、JAK/STAT、MAPK/ERK、膜转运体与离子通道、代谢酶与蛋白酶、神经信号、NF-κB、PI3K/Akt/mTOR、PROTAC、蛋白酪氨酸激酶/受体酪氨酸激酶、干细胞/Wnt、TGF-β/Smad 及维生素 D/核受体等研究方向，为肿瘤、感染、炎症与免疫、神经系统疾病、代谢性疾病、心血管疾病和内分泌研究提供多维度的产品选择，助力客户发表文献超 80,000 篇。

相关产品可根据具体情况提供化学结构、作用靶点、生物活性、纯度、溶解度、体内外研究信息、参考文献及质量分析报告 (COA)等资料。

客户发表文献：
[1]. Nature. 2026 Sep;657(8131):549-558.
[2]. Nature. 2026 Sep;657(8132):755-764.
[3]. Nature. 2026 Sep;657(8133):1027-1034.
[4]. Nature. 2026 Sep;657(8131):477-486.
[5].Nature. 2026 Sep;657(8132):789-799.
[6]. Nature. 2026 Sep;657(8131):517-524.
[7]. Nature. 2026 Sep;657(8133):1045-1052.
[8]. Cell. 2026 Sep 14:S0092-8674(26)01003-2.
[9]. Cell. 2026 Sep 3;189(18):5688-5705.e13.
[10]. Cell. 2026 Sep 2:S0092-8674(26)00937-2.

参考文献：
[1]. Lazareno, S., N.J. Buckley, and F.F. Roberts, Characterization of muscarinic M4 binding sites in rabbit lung, chicken heart, and NG108-15 cells. Mol Pharmacol, 1990. 38(6): p. 805-15.
[2]. Hernandez, M., et al., Different muscarinic receptor subtypes mediating the phasic activity and basal tone of pig isolated intravesical ureter. Br J Pharmacol, 1993. 110(4): p. 1413-20.
[3]. Veeraragavan S, et al. The modulation of fragile X behaviors by the muscarinic M4 antagonist, tropicamide. Behav Neurosci. 2011 Oct;125(5):783-90.
[4]. Betz AJ, et al. The muscarinic receptor antagonist tropicamide suppresses tremulous jaw movements in a rodent model of parkinsonian tremor: possible role of M4 receptors. Psychopharmacology (Berl). 2007 Oct;194(3):347-59.

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