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CAS: 150322-43-3
分子式: C20H20FNO3S
分子量: 373.44
中文名称: 
普拉格雷
乙酸5-[2-环丙基-1-(2-氟苯基)-2-氧乙基]-4,5,6,7-四氢噻吩并[3,2-c]吡啶-2-酯
英文名称: 
prasugrel
5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-tetrahydrothieno[3,2-c]pyridin-2-yl acetate
推荐供应商
货号品牌产品名称规格包装、参考价格
P832999MACKLINPrasugrel≥99%180元/500mg;   346元/1g;   1052元/5g;   咨询
储存:2~8℃,干燥,密封
状态:浅黄色到红黄色晶体粉末
P794733MACKLINPrasugrel10mM in DMSO185元/1ml;   咨询
储存:-20°C
P2040TCIPrasugrel>98.0%(T)(HPLC)290元/200MG;   咨询

基本信息

纯度/分析方法>98.0%(T)(HPLC)
分子式/分子量C20H20FNO3S = 373.44
外观与形状(20℃)固体
储存温度0-10℃
应避免的情况加热
Reaxys-RN9008623
PubChem物质ID172089108
MDL编号MFCD09954140

技术规格

AppearanceLight yellow to Yellow to Orange powder to crystal
Purity(HPLC)min. 98.0 area%
Purity(Nonaqueous Titration)min. 98.0 %
Melting point120.0 to 124.0 ℃

物性(参考值)

熔点122 ℃
837013J&KPrasugrel99%966元/10mg;   咨询

基本信息

分子式C20H20FNO3S
分子量373.45
MDL编码MFCD09954140

安全信息

防范说明P262
WGK3
C46148Alfa AesarPrasugrel98%1549元/250mg;   5065元/1g;   咨询

基本信息

Ref#
46148

分子式
C20H20FNO3S

分子量
182.18

GHS危害和防范说明

GHS符号

Hazard Statements
H302
Harmful if swallowed.

Precautionary Statements
P301+P330+P331 P312 P264

SML0331Sigma-AldrichPrasugrel≥98% (HPLC)1068.65元/10 MG;   4325.49元/50 MG;   咨询

产品说明

包装

10, 50 mg in glass bottle

生化/生理作用

Prasugrel is a thienopyridine prodrug and is considered to be more potent than clopidogrel. It shows a faster generation and also reduces thrombotic events. Prasugrel is less dependent on the CYP (cytochrome P450) enzymes for its conversion to active metabolite.
Prasugrel is a platelet inhibitor that reduces the aggregation of platelets by irreversible binding to P2Y12 receptors. Prasugrel interacts in an irreversible manner with the residues Cys97 and Cys175 of the human P2Y12-receptor.

特点和优势

This compound is featured on the P2 Receptors: P2Y G-Protein Family page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

基本信息

经验(实验)分子式C20H20FNO3S
分子量373.44
MDL编号MFCD09954140
PubChem化学物质编号329825336
NACRESNA.77

产品性质

质量水平100
测定≥98% (HPLC)
形式powder
颜色 white to beige
溶解性DMSO: >5 mg/mL (warmed at 60 ℃)
储存温度2-8℃
SMILES stringCC(=O)Oc1cc2CN(CCc2s1)C(C(=O)C3CC3)c4ccccc4F
InChI1S/C20H20FNO3S/c1-12(23)25-18-10-14-11-22(9-8-17(14)26-18)19(20(24)13-6-7-13)15-4-2-3-5-16(15)21/h2-5,10,13,19H,6-9,11H2,1H3
InChI keyDTGLZDAWLRGWQN-UHFFFAOYSA-N
Gene Informationhuman ... P2RY12(64805)

安全信息

储存分类代码13 - Non Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
Y0002119Prasugrel for system suitabilityEuropean Pharmacopoeia (EP) Reference Standard1259.15元/ ;   咨询

产品说明

一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

生化/生理作用

Prasugrel is a platelet inhibitor that reduces the aggregation of platelets by irreversible binding to P2Y12 receptors. Prasugrel interacts in an irreversible manner with the residues Cys97 and Cys175 of the human P2Y12-receptor.

包装

Unit quantity: 10 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

其他说明

Sales restrictions may apply.

基本信息

经验(实验)分子式C20H20FNO3S
分子量373.44
MDL编号MFCD09954140

产品性质

manufacturer/tradenameEDQM
储存温度2-8℃
SMILES stringCC(=O)Oc1cc2CN(CCc2s1)C(C(=O)C3CC3)c4ccccc4F
InChI1S/C20H20FNO3S/c1-12(23)25-18-10-14-11-22(9-8-17(14)26-18)19(20(24)13-6-7-13)15-4-2-3-5-16(15)21/h2-5,10,13,19H,6-9,11H2,1H3
InChI keyDTGLZDAWLRGWQN-UHFFFAOYSA-N
Gene Informationhuman ... P2RY12(64805)

安全信息

储存分类代码11 - Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
390330FluorochemPrasugrel95%4686元/1g;   14080元/5g;   咨询

基本信息

CAS Number150322-43-3
MDL NumberMFCD09954140
Melting Point122℃

安全信息

图形或危害标志
危险性说明 H315: Causes skin irritation.
H319: Causes serious eye irritation.
H335: May cause respiratory irritation.
防范说明 P233: Keep container tightly closed.
P260: Do not breathe .
P261: Avoid breathing .
P264: Wash hands thoroughly after handling.
P271: Use only outdoors or in a well-ventilated area.
P280: Wear .
P302 + P352: IF ON SKIN: Wash with plenty of soap and water.
P304: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing..
P304 + P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P312: Call a POISON CENTER or doctor/physician if you feel unwell.
P321: Specific treatment (see relevant procedures. on this label).
P332 + P313: If skin irritation occurs: Get medical advice/ attention.
P337 + P313: If eye irritation persists: Get medical advice/attention.
P340: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P362: Take off contaminated clothing and wash before reuse.
P403: Store in a well-ventilated place.
P403 + P233: Store in a well-ventilated place. Keep container tightly closed.
P405: Store locked up.
P501: Dispose of contents/container to in accordance with local regulation .
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