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CAS: 150-13-0
分子式: C7H7NO2
分子量: 137.14
熔点: 186-189℃
中文名称: 
维生素Bx
对氨基苯甲酸
4-氨基苯甲酸
对酸
英文名称: 
4-Aminobenzoesαure
p-Aminobenzoesαure
4-Amino-benzoic acid
p-Aminobenzoesaure
Benzoic acid,4-amino-
p-Aminobenzoic acid
4-amino-Benzoic acid
4-Aminobenzoic acid
p-amino-benzoic aci
1-amino-4-carboxybenzene
4-carboxyaniline
acido p-aminobenzoico
amben
aminobenzoic acid
anti-chromotrichia factor
anticanitic vitamin
antichromotrichia factor
bacterial vitamin h1
4-amino-benzoic aci
chromotrichia factor
H-4-Abz-OH
gamma-aminobenzoic acid
kyselina p-aminobenzoova
p-carboxyaniline
p-carboxyphenylamine
pab
paba
pabacyd
pabafilm
pabanol
para-aminobenzoic acid
paraminol
paranate
potaba
romavit
rvpaba
sunbrella
trichochromogenic factor
vitamin bx
vitamin h
vitamin h'
4-aminobenzoic
p-amino
p-amino benzoic acid
p-aminobenzoicacid
展开更多英文名
性质描述: 白色单斜棱晶。熔点188-189℃,相对密度1.374(25/4℃)。易溶于沸水,能溶于醇、醚、乙酸乙酯和冰醋酸,微溶于水及苯,不溶于石油醚。5%溶液的pH值为3.5。它是机体细胞生长和分裂所必需的物质叶酸的组成成分之一,在酵母、肝脏、麸皮,麦芽中含量甚高。
生产方法: 在反应锅内依次加入水、氯化钠、盐酸。开动搅拌并升温至50-60℃,加入9/10量的铁粉,继续升温到98-102℃,保温1h,停止加热,于95℃慢慢加入对硝基苯甲酸,约1-1.5h加完,补加铁粉,在98-102℃保温1h,放冷至80℃,加入30%液碱调节pH=8.5-9,压滤,用少量水洗,滤液与少量洗液合并,压入酸析锅,冷至30-34℃,加入保险粉脱色,过滤。滤液加酸调节pH=3.5-4,继续冷至10℃以下,甩水、干燥即得成品。收率84-88%。(2)由对硝基苯甲酸经催化加氢而得在1000ml烧杯中加入工业品对硝基苯甲酸及水,在搅拌下用22%氢氧化钠调整pH=6-7,然后加阮尼镍,在搅拌下把料液抽入摇摆式高压釜中,分别用氢气、氮气各置换两次、再充压至3.43MPa,在压力3.43-2.54MPa、温度134-140℃下反应5h左右,至氢压不下降为终点。反应结束后过滤、干燥而得成品。收率80%以上。
用途: 染料和医药中间体。用于生产活性红M-80,M-10B,活性红紫X-2R等染料以及制取氰基苯甲酸生产药物对羧基苄胺。对氨基苯甲酸可用作防晒剂,其衍生物对二甲氨基甲酸辛酯,是优良的防晒剂,商品名称Padimate O.
推荐供应商
货号品牌产品名称规格包装、参考价格详情
A800693MACKLIN对氨基苯甲酸分析标准品445元/100mg;   展开
储存:室温,避光
状态:白色粉末
767465MACKLIN对氨基苯甲酸≥99%, 用于合成195元/250g;   585元/1kg;   展开
储存:室温, 避光
状态:白色粉末
A821333MACKLIN对氨基苯甲酸97%(GC)28元/25g;   35元/100g;   102元/500g;   488元/2.5kg;   展开
储存:室温,避光
状态:白色粉末
A800692MACKLIN对氨基苯甲酸试剂级, 99%32元/25g;   64元/100g;   208元/500g;   854元/2.5kg;   2989元/10kg;   展开
储存:室温,避光
状态:白色粉末
A0269TCI4-Aminobenzoic Acid>99.0%(T)(HPLC)135元/25G;   275元/100G;   505元/500G;   展开

基本信息

纯度/分析方法>99.0%(T)(HPLC)
分子式/分子量C7H7NO2 = 137.14
外观与形状(20℃)固体
储存在惰性气体下存放于惰性气体之中
应避免的情况光,空气
Reaxys-RN471605
PubChem物质ID87561924
SDBS (AIST Spectral DB)1152
Merck Index (14)423
MDL编号MFCD00007894

技术规格

AppearanceWhite to Light yellow to Light orange powder to crystal
Purity(HPLC)min. 99.0 area%
Purity(Neutralization titration)min. 99.0 %
Solubility in hot Wateralmost transparency

物性(参考值)

熔点189 ℃
水溶性实际上不溶
在水中的溶解度6 g/l   25 ℃
溶解性(可溶于)乙醚,醇
溶解性(微溶于)

安全信息

图形或危害标志
信号词警告
危险性说明H302 : 吞咽有害。
H315 : 造成皮肤刺激。
H319 : 造成严重眼刺激。
H317 : 可能造成皮肤过敏反应。
防范说明P501 : 将内装物/容器送到批准的废物处理厂处理。
P261 : 避免吸入粉尘/烟/气体/烟雾/蒸气/喷雾。
P272 : 受沾染的工作服不得带出工作场地。
P270 : 使用本产品时不要进食、饮水或吸烟。
P264 : 作业后彻底清洗皮肤。
P280 : 戴防护手套/戴防护眼罩/戴防护面具。
P302 + P352 : 如皮肤沾染:用水充分清洗。
P337 + P313 : 如仍觉眼刺激:求医/就诊。
P305 + P351 + P338 : 如进入眼睛:用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出,取出隐形眼镜。继续冲洗。
P362+P364 : 脱掉沾污的衣服,清洗后方可重新使用。
P333 + P313 : 如发生皮肤刺激或皮疹:求医/就诊。
P301 + P312 + P330 : 如误吞咽:如感觉不适,呼叫急救中心/医生。漱口。

相关法规

RTECS#DG1400000
244122J&K4-Aminobenzoic Acid99%66元/50G;   239元/250G;   721元/1KG;   展开

基本信息

分子式C7H7NO2
分子量137.14
熔点186-189
密度1.374
MDL编码MFCD00007894
Beilstein471605
Merck14,423
EINECS 编号205-753-0

安全信息

图形或危害标志
提示语Warning
危险说明H315
H319
H335
防范说明P261
P264
P280
P302+P352
P305+P351+P338
WGK2
RTECSDG1400000
TSCA
A12673Alfa Aesar4-Aminobenzoic Acid99%204元/50g;   371元/250g;   1981元/1000g;   展开

应用
4-Aminobenzoic acid acts as a gastric acid secretion inhibitor. It is employed as an intermediate in the synthesis of folate (Vitamin BX), azo dyes and cross linking agents. It is also useful in biomedical sector for the preparation of local anesthetic and ointments. It is widely used in industries to make pharmaceutical products, flavors and preservatives. It is actively involved as a UV-blocking ingredient in sun tan cosmetics.

备注
Air and light sensitive. Incompatible with ferric salts and oxidizing agents. May discolor on exposure to light and air. Keep the container tightly closed in a dry and well-ventilated place.

基本信息

MDL
MFCD00007894

EINECS
205-753-0

分子式
C7H7NO2

分子量
137.14

熔点
ca 187° dec.

密度
1.374

灵敏度
Air Sensitive. Light Sensitive. Ambient temperatures.

形态
Powder

溶解性
Slightly soluble in water. Soluble in methanol and diethyl ether.

Beilstein
471605

Merck
14,423

GHS危害和防范说明

GHS符号

Hazard Statements
H315-H319-H335
Causes skin irritation.Causes serious eye irritation.May cause respiratory irritation.

Precautionary Statements
P261-P280a-P305+P351+P338-P304+P340-P405-P501a
Avoid breathing dust/fume/gas/mist/vapours/spray.Wear protective gloves and eye/face protection.IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing.Store locked up.Dispose of contents/container in accordance with local/regional/national/international regulations.

安全信息

危险类别
36/37/38
Irritating to eyes, respiratory system and skin.

安全等级
26-37-60
In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.This material and its container must be disposed of as hazardous waste

RTECS
DG1400000

TSCA

C14621Alfa Aesar4-Aminobenzoic Acid99%779元/250g;   2240元/1kg;   7761元/5kg;   展开

基本信息

Ref#
14621

MDL
7894

分子式
C7 H7 N O2

分子量
137.14

形态
Crystalline

A9878Sigma-Aldrich4-Aminobenzoic AcidReagentPlus®, ≥99%297.68元/5 G;   322.5元/25 G;   680.36元/100 G;   展开

产品说明

应用

4-氨基苯甲酸(4-ABA)可用于合成:

  • 基于4-ABA,具有良好的抗菌活性的席夫碱。
  • 硅胶支持物上的4-ABA的Co(II)和Mn(II)盐,可用作将硫醇氧化成二硫化物的催化剂。
  • 4-氨基-3-溴苯甲酸。
  • 固化剂, N-(4-羧基苯基)三苯甲酰亚胺(NCPT)。

包装

5, 25, 100 g in glass bottle

法律信息

ReagentPlus is a registered trademark of sigma-aldrich Co. LLC

基本信息

线性分子式H2NC6H4CO2H
分子量137.14
Beilstein471605
EC 号205-753-0
MDL编号MFCD00007894
PubChem化学物质编号24891403
NACRESNA.22

产品性质

生物来源synthetic (organic)
质量水平100
产品线ReagentPlus®
测定≥99%
形式powder
reaction suitabilityreaction type: solution phase peptide synthesis
mp187-189 ℃ (lit.)
溶解性ethanol: 50 mg/mL, clear, colorless to faintly yellow
密度1.374 g/mL at 25 ℃ (lit.)
application(s)peptide synthesis
储存温度2-8℃
SMILES stringNc1ccc(cc1)C(O)=O
InChI1S/C7H7NO2/c8-6-3-1-5(2-4-6)7(9)10/h1-4H,8H2,(H,9,10)
InChI keyALYNCZNDIQEVRV-UHFFFAOYSA-N

安全信息

储存分类代码11 - Combustible Solids
WGKWGK 2
闪点(F)339.8 °F
闪点(C)171 ℃
个人防护装备dust mask type N95 (US), Eyeshields, Faceshields, Gloves
100536Sigma-Aldrich4-Aminobenzoic AcidReagentPlus®, 99%188.66元/50 G;   303.2元/250 G;   1152.14元/1 KG;   3509.64元/5 KG;   展开

产品说明

一般描述

4-氨基苯甲酸 (4-ABA) 作为细菌辅助因子,参与叶酸的合成。它是一种通过线性氢键结合进行结构扩展的通用试剂,涉及羧酸和胺官能团。用氨基阳离子自由基法在玻碳电极 (GCE) 上制备了 4-ABA 单层膜。合成了 4-ABA 的分子加合物,用红外光谱和 X-射线衍射方法对其进行了表征。

应用

4-氨基苯甲酸可用于下列研究:

  • 玻碳电极的共价修饰。
  • 1,4-(2-氯亚苯基)氨基苯甲酸(席夫碱)的合成。
  • 分光光度法测定微量多巴胺、甲基多巴和左旋多巴。
  • 5-磺基水杨酸与 1:1 质子转移化合物的合成。

包装

50, 250 g in poly bottle
1 kg in poly bottle
5 kg in poly drum

法律信息

ReagentPlus is a registered trademark of sigma-aldrich Co. LLC

基本信息

线性分子式H2NC6H4CO2H
分子量137.14
Beilstein471605
EC 号205-753-0
MDL编号MFCD00007894
eCl@ss32160406
PubChem化学物质编号22435039

产品性质

质量水平200
产品线ReagentPlus®
测定99%
reaction suitabilityreaction type: solution phase peptide synthesis
mp187-189 ℃ (lit.)
溶解性95% ethanol: soluble 5%, clear to slightly hazy, colorless to yellow
密度1.374 g/mL at 25 ℃ (lit.)
application(s)peptide synthesis
SMILES stringNc1ccc(cc1)C(O)=O
InChI1S/C7H7NO2/c8-6-3-1-5(2-4-6)7(9)10/h1-4H,8H2,(H,9,10)
InChI keyALYNCZNDIQEVRV-UHFFFAOYSA-N

安全信息

储存分类代码11 - Combustible Solids
WGKWGK 2
闪点(F)339.8 °F
闪点(C)171 ℃
个人防护装备dust mask type N95 (US), Eyeshields, Faceshields, Gloves
01973Supelco4-Aminobenzoic Acidanalytical standard2389.6元/100MG;   展开

产品说明

包装

无底玻璃瓶。内含物装在插入的融合锥内。

其他说明

Ion Mobility: TWCCSN2 value of 133.2 Å2 [M+H]+

The collision cross section (CCS) measurement was provided by Waters Corporation, using the SYNAPT XS mass spectrometer.
For a description and overview of how ion mobility enables the measurement of the CCS of an ion visit ims.waters.com.
Further information on the SYNAPT XS mass spectrometer can be found on the IMS microsite and product webpage.

TWCCS measurements are expected to be within 2% of this reference value.

P/N 01973 is part of the Waters Extractables & Leachables UNIFI scientific library which can be downloaded from Waters Marketplace.

基本信息

线性分子式H2NC6H4CO2H
分子量137.14
Beilstein471605
EC 号205-753-0
MDL编号MFCD00007894
PubChem化学物质编号329747378
NACRESNA.24

产品性质

质量水平100
等级analytical standard
测定≥98.0% (HPLC)
保质期limited shelf life, expiry date on the label
technique(s)HPLC: suitable
gas chromatography (GC): suitable
mp186-188 ℃
187-189 ℃ (lit.)
密度1.374 g/mL at 25 ℃ (lit.)
application(s)cleaning products
cosmetics
environmental
food and beverages
personal care
格式neat
SMILES stringNc1ccc(cc1)C(O)=O
InChI1S/C7H7NO2/c8-6-3-1-5(2-4-6)7(9)10/h1-4H,8H2,(H,9,10)
InChI keyALYNCZNDIQEVRV-UHFFFAOYSA-N

安全信息

危险声明H412
预防措施声明P273 - P501
危险分类Aquatic Chronic 3
储存分类代码11 - Combustible Solids
WGKWGK 2
闪点(F)339.8 °F
闪点(C)171 ℃
429767Sigma-Aldrich4-Aminobenzoic Acidpurified by sublimation, ≥99%245.93元/1 G;   1313.15元/10 G;   展开

基本信息

线性分子式H2NC6H4CO2H
分子量137.14
Beilstein471605
EC 号205-753-0
MDL编号MFCD00007894
eCl@ss32160406
PubChem化学物质编号24866888
NACRESNA.22

产品性质

质量水平100
测定≥99%
纯化方式sublimation
reaction suitabilityreaction type: solution phase peptide synthesis
mp187-189 ℃ (lit.)
密度1.374 g/mL at 25 ℃ (lit.)
application(s)peptide synthesis
SMILES stringNc1ccc(cc1)C(O)=O
InChI1S/C7H7NO2/c8-6-3-1-5(2-4-6)7(9)10/h1-4H,8H2,(H,9,10)
InChI keyALYNCZNDIQEVRV-UHFFFAOYSA-N

安全信息

储存分类代码11 - Combustible Solids
WGKWGK 2
闪点(F)339.8 °F
闪点(C)171 ℃
个人防护装备dust mask type N95 (US), Eyeshields, Faceshields, Gloves
Y00001734-Aminobenzoic AcidEuropean Pharmacopoeia (EP) Reference Standard1572.27元/ ;   展开

产品说明

一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

包装

Unit quantity: 60 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

注意

Please find SDS provided by EDQM here..

其他说明

Sales restrictions may apply.

基本信息

线性分子式H2NC6H4CO2H
分子量137.14
Beilstein471605
MDL编号MFCD00007894
PubChem化学物质编号329830871
NACRESNA.24

产品性质

等级pharmaceutical primary standard
agencyEP Reference Standard
manufacturer/tradenameEDQM
mp187-189 ℃ (lit.)
密度1.374 g/mL at 25 ℃ (lit.)
application(s)pharmaceutical (small molecule)
格式neat
储存温度2-8℃
SMILES stringNc1ccc(cc1)C(O)=O
InChI1S/C7H7NO2/c8-6-3-1-5(2-4-6)7(9)10/h1-4H,8H2,(H,9,10)
InChI keyALYNCZNDIQEVRV-UHFFFAOYSA-N

安全信息

储存分类代码11 - Combustible Solids
WGKWGK 2
闪点(F)339.8 °F
闪点(C)171 ℃
8.22312Sigma-Aldrich4-Aminobenzoic Acidfor synthesis496.4元/250 G;   848.12元/1 KG;   展开

产品说明

分析说明

含量(酸度): ≥ 99.0 %
熔程(下限值): ≥ 185 °C
熔程(上限值): ≤ 188 °C
同一性(IR):通过测试

基本信息

经验(实验)分子式C7H7NO2
分子量137.14
MDL编号MFCD00007894
EC索引号205-753-0

产品性质

质量水平200
测定≥99.0% (acidimetric)
效能6000 mg/kg LD50, oral (Rat)
pH值(酸碱度)3.5 (20 ℃, 5 g/L in H2O)
mp186-189 ℃
密度1.38 g/cm3 at 20 ℃
堆积密度200 kg/m3
储存温度2-30℃
InChI1S/C7H7NO2/c8-6-3-1-5(2-4-6)7(9)10/h1-4H,8H2,(H,9,10)
InChI keyALYNCZNDIQEVRV-UHFFFAOYSA-N

安全信息

危险声明H412
预防措施声明P273 - P501
危险分类Aquatic Chronic 3
储存分类代码11 - Combustible Solids
WGKWGK 2
闪点(F)339.8 °F
闪点(C)171 ℃
V900614Sigma-Aldrich4-Aminobenzoic AcidVetec, reagent grade, 98%225.01元/100 G;   425.43元/500 G;   展开

产品说明

包装

100, 500 g in glass bottle

法律信息

Vetec is a trademark of sigma-aldrich International GmbH

基本信息

线性分子式H2NC6H4CO2H
分子量137.14
Beilstein471605
EC 号205-753-0
MDL编号MFCD00007894
PubChem化学物质编号329829974

产品性质

等级reagent grade
产品线Vetec
测定98%
形式powder
reaction suitabilityreaction type: solution phase peptide synthesis
颜色 white to off-white
mp187-189 ℃ (lit.)
密度1.374 g/mL at 25 ℃ (lit.)
SMILES stringNc1ccc(cc1)C(O)=O
InChI1S/C7H7NO2/c8-6-3-1-5(2-4-6)7(9)10/h1-4H,8H2,(H,9,10)
InChI keyALYNCZNDIQEVRV-UHFFFAOYSA-N

安全信息

危险声明H412
预防措施声明P273 - P501
危险分类Aquatic Chronic 3
储存分类代码11 - Combustible Solids
WGKWGK 2
闪点(F)339.8 °F
闪点(C)171 ℃
1019803USPAminobenzoic acidUnited States Pharmacopeia (USP) Reference Standard3231.47元/200 MG;   展开

产品说明

一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

分析说明

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

其他说明

USP issued SDS can be found here.
Sales restrictions may apply.

基本信息

线性分子式H2NC6H4CO2H
分子量137.14
Beilstein471605
MDL编号MFCD00007894
PubChem化学物质编号329748978

产品性质

等级pharmaceutical primary standard
manufacturer/tradenameUSP
mp187-189 ℃ (lit.)
密度1.374 g/mL at 25 ℃ (lit.)
application(s)pharmaceutical (small molecule)
格式neat
SMILES stringNc1ccc(cc1)C(O)=O
InChI1S/C7H7NO2/c8-6-3-1-5(2-4-6)7(9)10/h1-4H,8H2,(H,9,10)
InChI keyALYNCZNDIQEVRV-UHFFFAOYSA-N

安全信息

储存分类代码11 - Combustible Solids
WGKWGK 2
闪点(F)339.8 °F
闪点(C)171 ℃
PHR1840SupelcoAminobenzoic acidPharmaceutical Secondary Standard; Certified Reference Material2391.32元/500 MG;   展开

产品说明

一般描述

用于质量控制的二级药物标准品为制药实验室和制造商制备内部工作标准品提供了一种方便、经济的替代方案。胺碘酮是一种抗心律失常药,用于预防和治疗室性心律失常和房颤。

应用

氨基苯甲酸可用作药物参考标准品,用于通过高效液相色谱法测定药物制剂中的分析物。
这些二级标准品是合格的有证标准物质。它们适用用于于多种分析应用,包括但不限于药物释放检测、用于定性和定量分析的药物方法开发、食品和饮料质量控制检测以及其他校准要求。

分析说明

这些二级标准品可溯源到USP、EP和BP一级标准品。

其他说明

该认证参考物质(CRM)根据ISO 17034ISO/IEC 17025进行生产和认证。有关此CRM使用的所有信息均可在分析证书上找到。

附注

欲查看此物质的分析证书样本,请在下面的对话框中输入 LRAC2774。这只是一个示例证书,可能与您收到的批次不符。

基本信息

线性分子式H2NC6H4CO2H
分子量137.14
Beilstein471605
EC 号205-753-0
MDL编号MFCD00007894
NACRESNA.24

产品性质

质量水平300
等级certified reference material
pharmaceutical secondary standard
CofAcurrent certificate can be downloaded
包装pkg of 500 mg
mp187-189 ℃ (lit.)
密度1.374 g/mL at 25 ℃ (lit.)
application(s)pharmaceutical
格式neat
药典可追溯性traceable to PhEur Y0000173
traceable to USP 1019803
储存温度2-30℃
SMILES stringNc1ccc(cc1)C(O)=O
InChI1S/C7H7NO2/c8-6-3-1-5(2-4-6)7(9)10/h1-4H,8H2,(H,9,10)
InChI keyALYNCZNDIQEVRV-UHFFFAOYSA-N

安全信息

储存分类代码11 - Combustible Solids
WGKWGK 2
闪点(F)339.8 °F
闪点(C)171 ℃
046699Fluorochem4-Aminobenzoic Acid98%264元/25g;   352元/100g;   990元/500g;   1716元/1kg;   3168元/2.5kg;   展开

基本信息

CAS Number150-13-0
MDL NumberMFCD00007894

安全信息

图形或危害标志
危险性说明 H315: Causes skin irritation.
H319: Causes serious eye irritation.
H335: May cause respiratory irritation.
防范说明 P233: Keep container tightly closed.
P260: Do not breathe .
P261: Avoid breathing .
P264: Wash hands thoroughly after handling.
P271: Use only outdoors or in a well-ventilated area.
P280: Wear .
P302 + P352: IF ON SKIN: Wash with plenty of soap and water.
P304: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing..
P304 + P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P312: Call a POISON CENTER or doctor/physician if you feel unwell.
P321: Specific treatment (see relevant procedures. on this label).
P332 + P313: If skin irritation occurs: Get medical advice/ attention.
P337 + P313: If eye irritation persists: Get medical advice/attention.
P340: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P362: Take off contaminated clothing and wash before reuse.
P403: Store in a well-ventilated place.
P403 + P233: Store in a well-ventilated place. Keep container tightly closed.
P405: Store locked up.
P501: Dispose of contents/container to in accordance with local regulation .
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