CAS 14930-96-2; cytochalasin

CAS:

14930-96-2

分子式:

C₂₉H₃₇NO₅

分子量:

479.61

熔点:

218-223 °C

英文名称:

cytochalasin

cytochalasinb

2h-oxacyclotetradec(2,3-d)isoindole-2,18(5h)-dione, 16-benzyl-6,7,8,9,10,12a,13

,14,15,15a, 16,17-dodecahydro-5,13-dihydroxy-9,15-dimethyl-14-methylene-, (e)-(

9R,12as,13S,15S,15as, 16as,18as)-5

(e,e)-(5S,9R,12as,13S,15S,15as,16S,18as)-16-benzyl-6,7,8,9,10,12a,13,14,15, 15a

,16,17-dodecahydro-5,13-dihydroxy-9,15-dimethyl-14-methylene-2h- oxacyclotetrad

ec[2,3-d]isoindole-2,18(5h)-dione

24-oxa(14)cytochalasa-6(12),13,21-triene-1,23-dione, 7,20-dihydroxy-16-methyl-1

(7S,13e,16R,20R,21e)-0-phenyl

9R,12as,13S,15S,15as,16as,18as)-5

,14,15,15a,16,17-dodecahydro-5,13-dihydroxy- 9,15-dimethyl-14-methylene-, (e,e)

9R,12as,13S,15S,15as,16S,18as)--(5

7,20-dihydroxy-10-phenyl-5,16-dimethyl-24-oxa-[14]cytochalas-6(12),13,21- trien

-23-one

cytochalasin b

phomin

3-d)isoindole-2,18(5h)-dione,16-benzyl-6,7,8,9,10,12a,13,14,15,15a,16,17-dodecahydro-5,13-dihydroxy-2h-oxacyclotetradec(

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推荐供应商

货号

品牌

产品名称

规格

包装、参考价格

详情

C805410

MACKLIN

细胞松弛素B

98%

719元/1mg; 2500元/5mg;

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储存：-20°C
状态：白色到浅黄色粉末

391163

J&K

Cytochalasin B

98%

715元/1MG; 2281元/5MG;

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基本信息

分子式	C₂₉H₃₇NO₅
分子量	479.60
熔点	221-223
MDL编码	MFCD00077704
Beilstein	1096207
Merck	14,2790
EINECS 编号	239-000-2
存储条件	Freezer -20℃

安全信息

图形或危害标志
提示语	Danger
危险说明	H300 H310 H330 H361
防范说明	P260 P264 P280 P284 P302+P350 P310
UN号码	1544
危险分类	6.1
包装等级	II
WGK	3
RTECS	RO0205000
TSCA	否

C6762

Sigma-Aldrich

Cytochalasin B from Drechslera dematioidea

≥98% (HPLC), powder

694.88元/1 MG; 2872.41元/5 MG; 4158.22元/10 MG; 8299.51元/25 MG; 14282.3元/50 MG;

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产品说明

一般描述

Cytochalasin B is a cell-permeable fungal toxin / mycotoxin that binds to the ′barbed′ end of actin / actin filaments. This binding leads to:

Disruption of actin filaments and of interaction of actin filaments in solution
Inhibition of actin polymerization
Inhibition of subunit association and dissociation

Cytochalasin B is widely used in studies of glucose transporters (GLUT). Cytochalasin B is also used as an integral part of various in vitro micronucleus assay protocols.

包装

1, 5, 10, 25, 50 mg in serum bottle

生化/生理作用

Cell permeable fungal toxin that disrupts contractile microfilaments by inhibiting actin polymerization. This, in turn, induces DNA fragmentation, inhibits cell division, and disrupts many cell processes. Inhibits glucose transport.
One of a group of fungal metabolites that interfere with a wide variety of cellular movements. Useful tool for characterizing some of the polymerization properties of actin, and in studies on cytokinesis. Probe for the two hexose-transport systems in rat L6 myoblasts.

基本信息

经验(实验)分子式	C₂₉H₃₇NO₅
分子量	479.61
Beilstein	1096207
EC 号	239-000-2
MDL编号	MFCD00077704
PubChem化学物质编号	24892890
NACRES	NA.32

产品性质

质量水平	300
测定	≥98% (HPLC)
形式	powder
颜色	white
溶解性	DMSO: 10 mg/mL
作用机制	DNA synthesis \| interferes
抗生素抗菌谱	fungi
储存温度	−20℃
SMILES string	C[C@@H]1CCC[C@@H](O)\C=C\C(=O)O[C@]23[C@@H](\C=C\C1)[C@H](O)C(=C)[C@@H](C)[C@H]2[C@H](Cc4ccccc4)NC3=O
InChI	1S/C29H37NO5/c1-18-9-7-13-22(31)15-16-25(32)35-29-23(14-8-10-18)27(33)20(3)19(2)26(29)24(30-28(29)34)17-21-11-5-4-6-12-21/h4-6,8,11-12,14-16,18-19,22-24,26-27,31,33H,3,7,9-10,13,17H2,1-2H3,(H,30,34)/b14-8+,16-15+/t18-,19-,22-,23+,24+,26+,27-,29-/m1/s1
InChI key	GBOGMAARMMDZGR-TYHYBEHESA-N

安全信息

象形图
警示用语：	Danger
危险声明	H300 + H310 + H330 - H361
预防措施声明	P201 - P202 - P260 - P280 - P302 + P352 + P310 - P304 + P340 + P310
危险分类	Acute Tox. 1 Inhalation - Acute Tox. 2 Dermal - Acute Tox. 2 Oral - Repr. 2
储存分类代码	6.1A - Combustible, acute toxic Cat. 1 and 2 / very toxic hazardous materials
WGK	WGK 3
个人防护装备	Eyeshields, Faceshields, Gloves, type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges