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CAS: 1492-18-8
分子式: C20H21CaN7O7
分子量: 601.58
熔点: 240-250℃
中文名称: 
甲酰四氢叶酸钙
CF-CA
亚叶酸钙
亚叶酸钙(五水)
叶素钙
甲酰基-5,6,7,8-四氢叶酸钙盐
N5-甲酰-5,6,7,8-四氢叶酸钙
噬橙菌因子钙
N-{4-[(2-氨基-5-甲酰-5,6,7,8-四氢-4-羟基-6-蝶啶)甲基氨基]苯甲酰}-L-谷氨酸钙盐
英文名称: 
glutamic acid, n-(p-(((2-amino-5-formyl-5,6,7,8-tetrahydro-3-hydroxy-6-pteridin
calcium salt (1:1), l-yl)methyl) amino)benzoyl)
calcium 5-formyltetrahydrofolate
calcium folinate
calcium leucovorin
lederfoline
leucovorin calcium salt
folinic acid, calcium salt pentahydrate
Folinic acid calcium salt pentahydrate
用途: 用于解除氨基喋呤及甲氨喋呤过量而引起的毒性反应,还可用于治疗巨型红细胞贫血。
推荐供应商
货号品牌产品名称规格包装、参考价格详情
F809591MACKLIN亚叶酸钙,水合物98%193元/1g;   599元/5g;   2473元/25g;   7422元/100g;   展开
储存:室温
F792783MACKLIN亚叶酸钙, 水合物10mM in Water198元/1ml;   展开
储存:-20°C
C2235TCICalcium Folinate>98.0%(T)(HPLC)220元/1G;   730元/5G;   展开

基本信息

纯度/分析方法>98.0%(T)(HPLC)
分子式/分子量C20H21CaN7O7 = 511.51
外观与形状(20℃)固体
储存在惰性气体下存放于惰性气体之中
应避免的情况光,湿气 (吸湿)
包装和容器 1G-带有塑料内管的玻璃瓶 (查看图片)
相关CAS RN58-05-9&6035-45-6&2060570-47-8
Reaxys-RN5723924
PubChem物质ID87560126
MDL编号MFCD00006704

技术规格

AppearanceLight orange to Yellow to Green powder to crystaline
Purity(HPLC)min. 98.0 area%
Purity(Chelometric Titration)min. 98.0 %(calcd.on anh.substance)
Watermax. 17.0 %

物性(参考值)

水溶性可溶
溶解性(不溶于)乙醇

安全信息

图形或危害标志
信号词警告
危险性说明H315 : 造成皮肤刺激。
H319 : 造成严重眼刺激。
防范说明P264 : 作业后彻底清洗皮肤。
P280 : 戴防护手套/戴防护眼罩/戴防护面具。
P302 + P352 : 如皮肤沾染:用水充分清洗。
P337 + P313 : 如仍觉眼刺激:求医/就诊。
P305 + P351 + P338 : 如进入眼睛:用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出,取出隐形眼镜。继续冲洗。
P362+P364 : 脱掉沾污的衣服,清洗后方可重新使用。
P332 + P313 : 如发生皮肤刺激:求医/就诊。

相关法规

RTECS#MA0600500
332047J&KFolinic acid calcium salt hydrate98%494元/1G;   1568元/5G;   展开

基本信息

分子式C20H21CaN7O7·xH2O
分子量511.51(anhydrous)
熔点240-250
MDL编码MFCD00006704
Beilstein5723924

一般描述

亚叶酸,也称亚叶酸钙,通常以无定形粉末形式存在并且没有气味。这种维生素B9的活化形式为灰白色至浅米色。叶酸(FA)是水溶性维生素。亚叶酸是四氢叶酸的5-甲酰基衍生物,是叶酸的还原形式。5-甲酰基-5,6,7,8-四氢叶酸的非对映异构体的(6R,S)-混合物钙盐。

应用

亚叶酸钙盐水合物已被用于制备外用的1%和2.5%亚叶酸乳膏,可用于伤口愈合研究。它还被用作化学成分明确的中国仓鼠卵巢培养基(CD-CHO)的成分,用于培养CHO DUKX B11。叶酸拮抗剂通过结合二氢叶酸还原酶并阻滞叶酸转化为四氢叶酸盐发挥作用,而亚叶酸钙则可抵消叶酸拮抗剂的作用。在医学上,亚叶酸钙在甲氨蝶呤治疗后用于降低甲氨蝶呤的毒性。亚叶酸钙还可用于增强癌症治疗中 5-氟尿嘧啶的细胞毒性效应。

生化/生理作用

亚叶酸可作为辅因子并参与一碳转移反应(one-carbon-transfer reaction)。它有助于改善大鼠的伤口愈合。亚叶酸在自闭症儿童中起重要作用,可增强其言语交流。

安全信息

图形或危害标志
提示语Danger
危险说明H315
H317
H319
H334
H335
防范说明P261
P280
P305+P351+P338
P342+P311
WGK3
RTECSMA0600500
H60181Alfa AesarFolinic acid calcium salt hydrate98%2369元/250mg;   6697元/1g;   展开

基本信息

MDL
MFCD00149463

EINECS
216-082-8

分子式
C20H21CaN7O7?xH2O

分子量
511.51 (anhy)

形态
Solid

Beilstein
5723924

GHS危害和防范说明

GHS符号

Hazard Statements
H315-H319-H334-H317-H335
Causes skin irritation.Causes serious eye irritation.May cause allergy or asthma symptoms or breathing difficulties if inhaled.May cause an allergic skin reaction.May cause respiratory irritation.

Precautionary Statements
P284-P261-P280a-P305+P351+P338-P405-P501a
Wear respiratory protection.Avoid breathing dust/fume/gas/mist/vapours/spray.Wear protective gloves and eye/face protection.IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.Store locked up.Dispose of contents/container in accordance with local/regional/national/international regulations.

安全信息

危险类别
36/37/38-42/43
Irritating to eyes, respiratory system and skin.May cause sensitization by inhalation and skin contact.

安全等级
22-24-26-37-45-60
Do not breathe dust.Avoid contact with skin.In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).This material and its container must be disposed of as hazardous waste

欧盟危险品标志

TSCA

PHR1541SupelcoLeucovorin CalciumPharmaceutical Secondary Standard; Certified Reference Material1596.92元/1 G;   展开

产品说明

一般描述

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

应用

Leucovorin Calcium may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by high performance liquid chromatography (HPLC).
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

分析说明

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

其他说明

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

附注

To see an example of a Certificate of Analysis for this material enter LRAC1687 in the slot below. This is an example certificate only and may not be the lot that you receive.

基本信息

经验(实验)分子式C20H21CaN7O7
分子量511.50
EC 号216-082-8
NACRESNA.24

产品性质

质量水平300
等级certified reference material
pharmaceutical secondary standard
CofAcurrent certificate can be downloaded
包装ampule of 1 g
technique(s)HPLC: suitable
gas chromatography (GC): suitable
application(s)pharmaceutical (small molecule)
格式neat
药典可追溯性traceable to BP 923
traceable to PhEur C0250000
traceable to USP 1358004
储存温度2-8℃
InChI1S/C20H23N7O7.Ca/c21-20-25-16-15(18(32)26-20)27(9-28)12(8-23-16)7-22-11-3-1-10(2-4-11)17(31)24-13(19(33)34)5-6-14(29)30;/h1-4,9,12-13,22H,5-8H2,(H,24,31)(H,29,30)(H,33,34)(H4,21,23,25,26,32);/q;+2/p-2/t12?,13-;/m0./s1
InChI keyKVUAALJSMIVURS-ZEDZUCNESA-L

安全信息

象形图GHS07GHS08
警示用语:Danger
危险声明H315 - H317 - H319 - H334 - H335
预防措施声明P280 - P302 + P352 - P305 + P351 + P338
危险分类Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3
靶器官Respiratory system
储存分类代码11 - Combustible Solids
WGKWGK 2
闪点(F)Not applicable
闪点(C)Not applicable
F7878SupelcoFolinic acid calcium salt hydrateanalytical standard1527.58元/100 MG;   4917.17元/500 MG;   9364.3元/1 G;   展开

产品说明

一般描述

亚叶酸钙盐水合物是一种广泛使用的癌症治疗药物,因为它可以减少毒副作用,并有助于改善药物在肿瘤组织中的蓄积。

应用

有关合适仪器技术的更多信息,请参考产品′s分析证书。如需进一步支持,请联系技术服务。
亚叶酸钙盐水合物已被用作一种测试化合物,以使用酶联免疫吸附测定(ELISA)技术研究其对参与神经炎症的小胶质细胞的影响。
亚叶酸钙盐水合物已被用作一种测试化合物,用于通过酶联免疫吸附测定(ELISA)技术研究其对参与神经炎症的小胶质细胞的影响。亚叶酸钙盐水合物已被用作一种分析试剂,用于通过湍流色谱-串联质谱联用法定量测定生物样品中的甲氨蝶呤及其代谢物。
叶酸拮抗剂通过结合二氢叶酸还原酶并阻滞叶酸转化为四氢叶酸盐发挥作用,而亚叶酸钙则可抵消叶酸拮抗剂的作用。在医学上,亚叶酸钙在甲氨蝶呤治疗后用于降低甲氨蝶呤的毒性。亚叶酸钙还可用于增强癌症治疗中 5-氟尿嘧啶的细胞毒性效应。

包装

1 g in glass bottle
100, 500 mg in glass bottle

基本信息

经验(实验)分子式C20H21CaN7O7 · xH2O
分子量511.50 (anhydrous basis)
Beilstein5723924
PubChem化学物质编号24894951
NACRESNA.24

产品性质

生物来源synthetic (organic)
质量水平100
等级analytical standard
测定≥90.0%
technique(s)HPLC: suitable
gas chromatography (GC): suitable
颜色 yellow to orange
mp240-250 ℃
application(s)forensics and toxicology
pharmaceutical (small molecule)
格式neat
SMILES string[Ca++].[H]O[H].[H]C(=O)N1C(CNc2ccc(cc2)C(=O)N[C@@H](CCC([O-])=O)C([O-])=O)CNc3nc(N)nc(O)c13

安全信息

象形图GHS07GHS08
警示用语:Danger
危险声明H315 - H317 - H319 - H334 - H335
预防措施声明P261 - P264 - P280 - P302 + P352 - P304 + P340 + P312 - P305 + P351 + P338
危险分类Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3
靶器官Respiratory system
储存分类代码11 - Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
47612Sigma-AldrichFolinic acid calcium salt hydrateBioXtra, ≥99.0% (HPLC)3118.83元/250 MG;   9867.42元/1 G;   展开

产品说明

一般描述

亚叶酸,也称亚叶酸钙,通常以无定形粉末形式存在并且没有气味。这种维生素B9的活化形式为灰白色至浅米色。叶酸(FA)是水溶性维生素。亚叶酸是四氢叶酸的5-甲酰基衍生物,是叶酸的还原形式。
5-甲酰基-5,6,7,8-四氢叶酸的非对映异构体的(6R,S)-混合物钙盐。

应用

亚叶酸钙盐水合物已被用于制备外用的1%和2.5%亚叶酸乳膏,可用于伤口愈合研究。它还被用作化学成分明确的中国仓鼠卵巢培养基(CD-CHO)的成分,用于培养CHO DUKX B11。
叶酸拮抗剂通过结合二氢叶酸还原酶并阻滞叶酸转化为四氢叶酸盐发挥作用,而亚叶酸钙则可抵消叶酸拮抗剂的作用。在医学上,亚叶酸钙在甲氨蝶呤治疗后用于降低甲氨蝶呤的毒性。亚叶酸钙还可用于增强癌症治疗中 5-氟尿嘧啶的细胞毒性效应。

生化/生理作用

亚叶酸可作为辅因子并参与一碳转移反应(one-carbon-transfer reaction)。它有助于改善大鼠的伤口愈合。亚叶酸在自闭症儿童中起重要作用,可增强其言语交流。

其他说明

综述

基本信息

经验(实验)分子式C20H21CaN7O7 · xH2O
分子量511.50 (anhydrous basis)
Beilstein5723924
PubChem化学物质编号24871209

产品性质

质量水平200
生物来源synthetic
产品线BioXtra
测定≥99.0% (HPLC)
形式powder or crystals
technique(s)cell culture | mammalian: suitable
颜色 white to faint yellow
mp240-250 ℃
application(s)cell analysis
SMILES string[Ca++].[H]O[H].[H]C(=O)N1C(CNc2ccc(cc2)C(=O)N[C@@H](CCC([O-])=O)C([O-])=O)CNc3nc(N)nc(O)c13

安全信息

象形图GHS07GHS08
警示用语:Danger
危险声明H315 - H317 - H319 - H334 - H335
预防措施声明P280 - P302 + P352 - P305 + P351 + P338
危险分类Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3
靶器官Respiratory system
储存分类代码11 - Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
个人防护装备dust mask type N95 (US), Eyeshields, Faceshields, Gloves
C0250000Calcium FolinateEuropean Pharmacopoeia (EP) Reference Standard1573.02元/ ;   展开

产品说明

一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia. Calcium folinate (CF) is a folic acid derivative. It is a naturally occurring compound that has a vital role in various metabolic pathways. Calcium folinate (CF) drug is also used in the treatment of anemia, during pregnancy.

应用

叶酸拮抗剂通过结合二氢叶酸还原酶并阻滞叶酸转化为四氢叶酸盐发挥作用,而亚叶酸钙则可抵消叶酸拮抗剂的作用。在医学上,亚叶酸钙在甲氨蝶呤治疗后用于降低甲氨蝶呤的毒性。亚叶酸钙还可用于增强癌症治疗中 5-氟尿嘧啶的细胞毒性效应。

包装

Unit quantity: 110 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

注意

Please find SDS provided by EDQM here..

其他说明

Sales restrictions may apply.

基本信息

经验(实验)分子式C20H21CaN7O7 · xH2O
分子量511.50 (anhydrous basis)
Beilstein5723924
NACRESNA.24

产品性质

生物来源synthetic
等级pharmaceutical primary standard
agencyEP
形式solid
manufacturer/tradenameEDQM
technique(s)gas chromatography (GC): suitable
liquid chromatography (LC): suitable
application(s)pharmaceutical (small molecule)
格式neat
储存温度2-8℃
SMILES string[Ca++].[H]O[H].[H]C(=O)N1C(CNc2ccc(cc2)C(=O)N[C@@H](CCC([O-])=O)C([O-])=O)CNc3nc(N)nc(O)c13

安全信息

象形图GHS07GHS08
警示用语:Danger
危险声明H315 - H317 - H319 - H334 - H335
预防措施声明P261 - P264 - P280 - P302 + P352 - P304 + P340 + P312 - P305 + P351 + P338
危险分类Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3
靶器官Respiratory system
储存分类代码11 - Combustible Solids
WGKWGK 2
闪点(F)Not applicable
闪点(C)Not applicable
Y0002071Calcium folinate for system suitabilityEuropean Pharmacopoeia (EP) Reference Standard1313.88元/ ;   展开

产品说明

一般描述

Calcium folinate, the reduced form of folic acid, finds application in the treatment of methotrexate overdose and in high-dose methotrexate chemotherapy as a chemotherapy protective drug to bring down the latter′s toxicity. When combined with fluorouracil, it is reported to be effective in the management of bowel cancer wherein it acts by inhibiting thymidylate synthase and augmenting the effect of fluorouracil.
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

应用

Calcium folinate for system suitability may be used as an analytical reference standard for the determination of the analyte in pharmaceutical formulations by liquid chromatography.
叶酸拮抗剂通过结合二氢叶酸还原酶并阻滞叶酸转化为四氢叶酸盐发挥作用,而亚叶酸钙则可抵消叶酸拮抗剂的作用。在医学上,亚叶酸钙在甲氨蝶呤治疗后用于降低甲氨蝶呤的毒性。亚叶酸钙还可用于增强癌症治疗中 5-氟尿嘧啶的细胞毒性效应。

包装

Unit quantity: 10 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

其他说明

Sales restrictions may apply.

基本信息

经验(实验)分子式C20H21CaN7O7 · xH2O
分子量511.50 (anhydrous basis)
Beilstein5723924

产品性质

生物来源synthetic
等级pharmaceutical primary standard
agencyEP
形式solid
manufacturer/tradenameEDQM
technique(s)gas chromatography (GC): suitable
liquid chromatography (LC): suitable
application(s)pharmaceutical (small molecule)
格式neat
储存温度−20℃
SMILES string[Ca++].[H]O[H].[H]C(=O)N1C(CNc2ccc(cc2)C(=O)N[C@@H](CCC([O-])=O)C([O-])=O)CNc3nc(N)nc(O)c13

安全信息

象形图GHS07GHS08
警示用语:Danger
危险声明H315 - H317 - H319 - H334 - H335
预防措施声明P261 - P264 - P280 - P280 - P304 + P340 + P312 - P342 + P311
危险分类Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3
靶器官Respiratory system
储存分类代码13 - Non Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
1358004USPLeucovorin CalciumUnited States Pharmacopeia (USP) Reference Standard3365.61元/500 MG;   展开

产品说明

一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

分析说明

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

其他说明

USP issued SDS can be found here.
Sales restrictions may apply.

基本信息

经验(实验)分子式C20H21CaN7O7
分子量511.50
NACRESNA.24

产品性质

等级pharmaceutical primary standard
manufacturer/tradenameUSP
application(s)pharmaceutical (small molecule)
格式neat
储存温度2-8℃
InChI1S/C20H23N7O7.Ca/c21-20-25-16-15(18(32)26-20)27(9-28)12(8-23-16)7-22-11-3-1-10(2-4-11)17(31)24-13(19(33)34)5-6-14(29)30;/h1-4,9,12-13,22H,5-8H2,(H,24,31)(H,29,30)(H,33,34)(H4,21,23,25,26,32);/q;+2/p-2/t12?,13-;/m0./s1
InChI keyKVUAALJSMIVURS-ZEDZUCNESA-L

安全信息

象形图GHS07GHS08
警示用语:Danger
危险声明H315 - H317 - H319 - H334 - H335
预防措施声明P261 - P280 - P284 - P304 + P340 - P305 + P351 + P338 - P342 + P311
危险分类Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3
靶器官Respiratory system
储存分类代码13 - Non Combustible Solids
WGKWGK 2
闪点(F)Not applicable
闪点(C)Not applicable
1286027USPFolic Acid Related Compound AUnited States Pharmacopeia (USP) Reference Standard3304.65元/50 MG;   展开

产品说明

一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

分析说明

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

其他说明

USP issued SDS can be found here.
Sales restrictions may apply.

基本信息

经验(实验)分子式C20H21CaN7O7
分子量511.50
NACRESNA.24

产品性质

等级pharmaceutical primary standard
manufacturer/tradenameUSP
application(s)pharmaceutical (small molecule)
格式neat
储存温度2-8℃
InChI1S/C20H23N7O7.Ca/c21-20-25-16-15(18(32)26-20)27(9-28)12(8-23-16)7-22-11-3-1-10(2-4-11)17(31)24-13(19(33)34)5-6-14(29)30;/h1-4,9,12-13,22H,5-8H2,(H,24,31)(H,29,30)(H,33,34)(H4,21,23,25,26,32);/q;+2/p-2/t12?,13-;/m0./s1
InChI keyKVUAALJSMIVURS-ZEDZUCNESA-L

安全信息

象形图GHS07GHS08
警示用语:Danger
危险声明H315 - H317 - H319 - H334 - H335
预防措施声明P261 - P280 - P284 - P304 + P340 - P305 + P351 + P338 - P342 + P311
危险分类Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3
靶器官Respiratory system
储存分类代码13 - Non Combustible Solids
WGKWGK 2
闪点(F)Not applicable
闪点(C)Not applicable
036567Fluorochem5-Formyl-5,6,7,8-tetrahydrofolic acid calcium salt97%374元/250mg;   836元/1g;   2706元/5g;   13200元/25g;   展开

基本信息

CAS Number1492-18-8
MDL NumberMFCD00006704

安全信息

图形或危害标志
危险性说明 H315: Causes skin irritation.
H319: Causes serious eye irritation.
H335: May cause respiratory irritation.
防范说明 P233: Keep container tightly closed.
P260: Do not breathe .
P261: Avoid breathing .
P264: Wash hands thoroughly after handling.
P271: Use only outdoors or in a well-ventilated area.
P280: Wear .
P302 + P352: IF ON SKIN: Wash with plenty of soap and water.
P304: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing..
P304 + P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P312: Call a POISON CENTER or doctor/physician if you feel unwell.
P321: Specific treatment (see relevant procedures. on this label).
P332 + P313: If skin irritation occurs: Get medical advice/ attention.
P337 + P313: If eye irritation persists: Get medical advice/attention.
P340: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P362: Take off contaminated clothing and wash before reuse.
P403: Store in a well-ventilated place.
P403 + P233: Store in a well-ventilated place. Keep container tightly closed.
P405: Store locked up.
P501: Dispose of contents/container to in accordance with local regulation .
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