CAS 148702-58-3; sb-204070 hydrochloride

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CAS:

148702-58-3

英文名称:

sb-204070 hydrochloride

(1-butyl-4-piperidinyl)methyl-8-amino-7-chloro-1,4-benzodioxane-5-carboxylate hydrochloride

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货号

品牌

产品名称

规格

包装、参考价格

详情

S3313

Sigma-Aldrich

SB-204070 hydrochloride

solid, ≥97% (HPLC)

8428.11元/5 MG;

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产品说明

应用

SB-204070 hydrochloride was used to study the role of 5-HT metabolites in trypsin-induced anion secretion in mouse cecum.

包装

5, 25 mg in glass bottle

生化/生理作用

SB-204070 is a highly potent and specific antagonist of 4-HT₄ receptor. It inhibits cholinergic and noncholinergic transmission and blocks the contractions of proximal colon in guinea pigs and relaxation of human colon circular smooth muscle.
Selective 5-HT₄ serotonin receptor antagonist.

法律信息

Manufactured and sold under exclusive license from GlaxoSmithKline Pharmaceuticals

基本信息

经验(实验)分子式	C₁₉H₂₇ClN₂O₄ · HCl
分子量	419.34
MDL编号	MFCD03453014
PubChem化学物质编号	24278704
NACRES	NA.77

产品性质

质量水平	100
测定	≥97% (HPLC)
形式	solid
mp	243-245 ℃ (lit.)
溶解性	H₂O: 20 mg/mL (with heating)
SMILES string	Cl[H].CCCCN1CCC(CC1)COC(=O)c2cc(Cl)c(N)c3OCCOc23
InChI	1S/C19H27ClN2O4.ClH/c1-2-3-6-22-7-4-13(5-8-22)12-26-19(23)14-11-15(20)16(21)18-17(14)24-9-10-25-18;/h11,13H,2-10,12,21H2,1H3;1H
InChI key	YEQGKAOSYSXEPU-UHFFFAOYSA-N
Gene Information	human ... HTR4(3360)

安全信息

储存分类代码	11 - Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable
个人防护装备	Eyeshields, Gloves, type N95 (US)

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