CAS 1476-52-4; desethylchloroquine

推荐供应商

货号

品牌

产品名称

规格

包装、参考价格

详情

D937724

MACKLIN

羟基氯喹EP杂质D-d5二盐酸

98%

733元/1mg; 2180元/5mg; 3585元/10mg;

展开

储存：2-8°C，密封，干燥
状态：白色到灰白色粉末或晶体

SMB00963

Sigma-Aldrich

Desethylchloroquine

≥95% (HPLC)

5063.47元/5 MG; 10850.3元/25 MG;

展开

产品说明

一般描述

Desethylchloroquine is a metabolite of hydroxychloroquine and chloroquine. Hydroxychloroquine and chloroquine have antimalarial properties and are used as a therapeutic for rheumatoid arthritis (RA), systemic lupus erythematosus (SLE) and other inflammatory rheumatic diseases. They have also been in the spotlight due to their activity on patients with COVID-19, the disease caused by the SARS-CoV-2 virus. Hydroxychloroquine and chloroquine interfere with lysosomal activity and autophagy, interact with membrane stability and alter signalling pathways and transcriptional activity, which can result in modulation of cytokine production. Their mode of action is still emerging and their metabolism is of great interest.

应用

Application: Metabolomics research

基本信息

经验(实验)分子式	C₁₆H₂₂ClN₃
分子量	291.82
MDL编号	MFCD00871808

产品性质

质量水平	200
生物来源	synthetic
等级	research grade
测定	≥95% (HPLC)
形式	powder or crystals
technique(s)	HPLC: suitable
颜色	white to off-white
运输	wet ice
储存温度	2-8℃
SMILES string	ClC(C=C1)=CC2=C1C(NC(CCCNCC)C)=CC=N2
InChI	1S/C16H22ClN3/c1-3-18-9-4-5-12(2)20-15-8-10-19-16-11-13(17)6-7-14(15)16/h6-8,10-12,18H,3-5,9H2,1-2H3,(H,19,20)
InChI key	MCYUUUTUAAGOOT-UHFFFAOYSA-N

安全信息

象形图
警示用语：	Warning
危险声明	H302
预防措施声明	P264 - P270 - P301 + P312 - P501
危险分类	Acute Tox. 4 Oral
储存分类代码	11 - Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable

1118350

USP

Chloroquine Related Compound D

United States Pharmacopeia (USP) Reference Standard

10218.8元/15 MG;

展开

产品说明

一般描述

Chloroquine Related Compound D is an impurity of chloroquine, which is a 9-aminoquinoline drug that effectively inhibits viral infections in humans.

应用

Chloroquine Related Compound D can be used as a pharmaceutical primary standard for the determination of the analyte in pharmaceutical formulations by liquid chromatography (LC) technique.

分析说明

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.

其他说明

USP issued SDS can be found here.
Sales restrictions may apply.

基本信息

经验(实验)分子式	C₁₆H₂₂ClN₃
分子量	291.82
MDL编号	MFCD00871808
NACRES	NA.24

产品性质

生物来源	synthetic
等级	pharmaceutical primary standard
agency	USP
形式	powder
包装	pkg of 15 mg
manufacturer/tradename	USP
储存条件	protect from light
颜色	tan
bp	343.4-347 °F (173—175℃; 845.06°F )
mp	176-215.6 °F (80—102℃)
溶解性	chloroform: soluble dichloromethane: soluble
密度	1.14 g/cm³
application(s)	pharmaceutical (small molecule)
格式	neat
储存温度	2-8℃
SMILES string	ClC(C=C1)=CC2=C1C(NC(CCCNCC)C)=CC=N2
InChI	1S/C16H22ClN3/c1-3-18-9-4-5-12(2)20-15-8-10-19-16-11-13(17)6-7-14(15)16/h6-8,10-12,18H,3-5,9H2,1-2H3,(H,19,20)
InChI key	MCYUUUTUAAGOOT-UHFFFAOYSA-N

安全信息

象形图
警示用语：	Warning
危险声明	H302
预防措施声明	P301 + P312 + P330
危险分类	Acute Tox. 4 Oral
储存分类代码	13 - Non Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable