CAS 147098-20-2; Rosuvastatin

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货号

品牌

产品名称

规格

包装、参考价格

R793916

MACKLIN

瑞舒伐他汀钙

10mM in DMSO

494元/1ml;

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储存：-20°C

R833152

MACKLIN

瑞舒伐他汀钙

≥99%

30元/25mg; 62元/100mg; 122元/1g; 375元/5g; 1337元/25g;

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储存：2~8℃,干燥,密封
状态：白色到灰白色到黄色固体

R0180

TCI

Rosuvastatin Calcium

>95.0%(HPLC)(N)

490元/200MG;

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基本信息

纯度/分析方法	>95.0%(HPLC)(N)
分子式/分子量	C₄₄H₅₄CaF₂N₆O₁₂S₂ = 1001.14
外观与形状(20℃)	固体
储存温度	<0℃
应避免的情况	加热
相关CAS RN	287714-41-4
Reaxys-RN	7740139
PubChem物质ID	253661249
Merck Index (14)	8270
MDL编号	MFCD04112702

技术规格

Appearance	White to Almost white powder to crystal
Purity(HPLC)	min. 95.0 area%
Purity(with Total Nitrogen)	min. 95.0 %
Purity(Chelometric Titration)	min. 90.0 %
Specific rotation [a]20/D	-7.0 to -10.0 deg(C=1, CHCL3)

物性(参考值)

熔点	160 ℃
比旋光度 [α]D	-8° (C=1,CHCl3)
最大吸收波长	243(Phosphate buffer sol.) nm

相关法规

RTECS#

MJ9675070

599342

J&K

Rosuvastatin Calcium

99%

930元/250MG; 2789元/1G;

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基本信息

分子式	C₂₂H₂₇Ca₀.5FN₃O₆S
分子量	500.57
熔点	>151
MDL编码	MFCD04112702
存储条件	Freezer -20℃

PHR1928

Supelco

Rosuvastatin Calcium

Pharmaceutical Secondary Standard; Certified Reference Material

3586.98元/1 G;

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产品说明

一般描述

Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards

分析说明

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

其他说明

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

附注

To see an example of a Certificate of Analysis for this material enter LRAC2081 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

基本信息

经验(实验)分子式	C₄₄H₅₄CaF₂N₆O₁₂S₂
分子量	1001.14
NACRES	NA.24

产品性质

质量水平	300
等级	certified reference material pharmaceutical secondary standard
形式	powder
CofA	current certificate can be downloaded
包装	pkg of 1 g
application(s)	pharmaceutical
药典可追溯性	traceable to PhEur Y0001719 traceable to USP 1606015
储存温度	-10 to -25℃
InChI	1S/2C22H28FN3O6S.Ca/c21-13(2)20-18(10-9-16(27)11-17(28)12-19(29)30)21(14-5-7-15(23)8-6-14)25-22(24-20)26(3)33(4,31)32;/h25-10,13,16-17,27-28H,11-12H2,1-4H3,(H,29,30);/q;;+2/p-2/b210-9+;/t216-,17-;/m11./s1
InChI key	LALFOYNTGMUKGG-BGRFNVSISA-L

安全信息

储存分类代码	13 - Non Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable

Y0001719

Rosuvastatin Calcium

European Pharmacopoeia (EP) Reference Standard

1277.32元/ ;

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产品说明

一般描述

本产品按照现行药典要求提供和指定。所有为支持本产品而提供的信息，包括 SDS 和任何产品信息小册子，均由药典颁发机构制定和发布。
如需进一步的信息和支持，请访问现行药典网站。

包装

单位数量：160 mg。可进行调整。本品按药典规定提供。有关当前单位数量，请见EDQM 参考目录

其他说明

可能适用相应的销售限制。

基本信息

经验(实验)分子式	C₄₄H₅₄CaF₂N₆O₁₂S₂
分子量	1001.14
NACRES	NA.24

产品性质

等级	pharmaceutical primary standard
manufacturer/tradename	EDQM
application(s)	pharmaceutical (small molecule)
格式	neat
储存温度	−20℃
InChI	1S/2C22H28FN3O6S.Ca/c21-13(2)20-18(10-9-16(27)11-17(28)12-19(29)30)21(14-5-7-15(23)8-6-14)25-22(24-20)26(3)33(4,31)32;/h25-10,13,16-17,27-28H,11-12H2,1-4H3,(H,29,30);/q;;+2/p-2/b210-9+;/t216-,17-;/m11./s1
InChI key	LALFOYNTGMUKGG-BGRFNVSISA-L

安全信息

储存分类代码	13 - Non Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable

Y0001721

Rosuvastatin for system suitability

European Pharmacopoeia (EP) Reference Standard

1277.32元/ ;

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产品说明

一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

包装

Unit quantity: 15 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

其他说明

Sales restrictions may apply.

基本信息

经验(实验)分子式	C₄₄H₅₄CaF₂N₆O₁₂S₂
分子量	1001.14
NACRES	NA.24

产品性质

等级	pharmaceutical primary standard
manufacturer/tradename	EDQM
application(s)	pharmaceutical (small molecule)
格式	neat
储存温度	2-8℃
InChI	1S/2C22H28FN3O6S.Ca/c21-13(2)20-18(10-9-16(27)11-17(28)12-19(29)30)21(14-5-7-15(23)8-6-14)25-22(24-20)26(3)33(4,31)32;/h25-10,13,16-17,27-28H,11-12H2,1-4H3,(H,29,30);/q;;+2/p-2/b210-9+;/t216-,17-;/m11./s1
InChI key	LALFOYNTGMUKGG-BGRFNVSISA-L

安全信息

储存分类代码	13 - Non Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable

SML1264

Sigma-Aldrich

Rosuvastatin Calcium

≥98% (HPLC)

1396.09元/10 MG; 4498.97元/50 MG;

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产品说明

一般描述

瑞舒伐他汀钙(ROS)具有1001.14的分子量。ROS是一种“他汀”类药物并且是3-羟基-3-甲基戊二酰的一种还原酶抑制剂。

应用

瑞舒伐他汀钙已被用于确定SIM、瑞舒伐他汀或PRA治疗对HeLa细胞中胆固醇和HMGCR水平的影响，并评估他汀类药物对葡萄糖体内平衡的体内作用。

包装

10, 50 mg in glass bottle

生化/生理作用

瑞舒伐他汀钙是羟甲基戊二酰辅酶A(HMG-CoA)还原酶的一种竞争性抑制剂，可催化HMG-CoA转化为甲羟戊酸，而这是胆固醇生物合成中的限速步骤。瑞舒伐他汀钙具有抗血脂效果，可用于降低血浆胆固醇水平，预防心血管疾病。

基本信息

经验(实验)分子式	C₂₂H₂₇FN₃O₆S · 0.5 Ca
分子量	500.57

产品性质

测定	≥98% (HPLC)
形式	powder
旋光性	[α]/D +12 to +18°, c = 1 in methanol: water (1:1)
储存条件	desiccated
颜色	white to beige
溶解性	DMSO: 10 mg/mL, clear
储存温度	2-8℃
InChI	1S/2C22H28FN3O6S.Ca/c21-13(2)20-18(10-9-16(27)11-17(28)12-19(29)30)21(14-5-7-15(23)8-6-14)25-22(24-20)26(3)33(4,31)32;/h25-10,13,16-17,27-28H,11-12H2,1-4H3,(H,29,30);/q;;+2/p-2/b210-9+;/t216-,17-;/m11./s1
InChI key	LALFOYNTGMUKGG-BGRFNVSISA-L

安全信息

储存分类代码	13 - Non Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable