CAS 14653-77-1; 2-((3-aminopropyl)amino)-ethanethio dihydrochloride

位置：首页 > 资料中心 > 化工字典 > 14653-77-1

CAS:

14653-77-1

分子式:

C₅H₁₆Cl₂N₂S

分子量:

207.16

英文名称:

2-((3-aminopropyl)amino)-ethanethio dihydrochloride

2-((3-aminopropyl)amino)ethanethiol dihydrochloride

wr 1065 hydrochloride

用途:

WR-1065 dihydrochloride 可以保护正常组织免受某些癌症药物的毒性作用，并通过 JNK 依赖性信号通路激活 p53。

推荐供应商

货号

品牌

产品名称

规格

包装、参考价格

W882261

MACKLIN

WR-1065 dihydrochloride

≥98%

352元/5mg; 403元/10mg;

咨询

储存：2-8℃

W2020

Sigma-Aldrich

WR-1065

≥98% (HPLC)

987.69元/10 MG; 3839.74元/50 MG;

咨询

产品说明

包装

10, 50 mg in glass bottle

生化/生理作用

WR-1065 is cytoprotective cell-permeable reactive oxygen species scavenger and p53 activator and re-activator. Recently shown to have antiretroviral activity and an active metabolite of Amifostine which selectively protects normal tissues from the damaging effects of anti-neoplastic radiation therapy.
WR-1065 is the active metabolite of the prodrug amifostine, generated by alkaline phosphatase. It is found to accumulate in many epithelial tissues. WR-1065 protects cellular membranes and DNA from free radical induced damage.

基本信息

经验(实验)分子式	C₅H₁₄N₂S · 2HCl
分子量	207.16
MDL编号	MFCD00460339
PubChem化学物质编号	329830444
NACRES	NA.77

产品性质

质量水平	100
测定	≥98% (HPLC)
形式	powder
储存条件	desiccated
颜色	white to off-white
溶解性	H₂O: ≥20 mg/mL
储存温度	−20℃
SMILES string	Cl.Cl.NCCCNCCS
InChI	1S/C5H14N2S.2ClH/c6-2-1-3-7-4-5-8;;/h7-8H,1-6H2;2*1H
InChI key	XDRLRDHLCIFZIW-UHFFFAOYSA-N

安全信息

象形图
警示用语：	Danger
危险声明	H302 - H318
预防措施声明	P280 - P305 + P351 + P338
危险分类	Acute Tox. 4 Oral - Eye Dam. 1
储存分类代码	13 - Non Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable

1019428

USP

Amifostine thiol

United States Pharmacopeia (USP) Reference Standard

10218.8元/50 MG;

咨询

产品说明

一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

生化/生理作用

WR-1065 is cytoprotective cell-permeable reactive oxygen species scavenger and p53 activator and re-activator. Recently shown to have antiretroviral activity and an active metabolite of Amifostine which selectively protects normal tissues from the damaging effects of anti-neoplastic radiation therapy.

分析说明

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.

其他说明

USP issued SDS can be found here.
Sales restrictions may apply.

基本信息

经验(实验)分子式	C₅H₁₄N₂S · 2HCl
分子量	207.16
MDL编号	MFCD00460339
PubChem化学物质编号	329748973
NACRES	NA.24

产品性质

等级	pharmaceutical primary standard
manufacturer/tradename	USP
application(s)	pharmaceutical (small molecule)
格式	neat
储存温度	−20℃
SMILES string	Cl.Cl.NCCCNCCS
InChI	1S/C5H14N2S.2ClH/c6-2-1-3-7-4-5-8;;/h7-8H,1-6H2;2*1H
InChI key	XDRLRDHLCIFZIW-UHFFFAOYSA-N

安全信息

象形图
警示用语：	Danger
危险声明	H302 - H318
预防措施声明	P280 - P301 + P312 + P330 - P305 + P351 + P338 + P310
危险分类	Acute Tox. 4 Oral - Eye Dam. 1
储存分类代码	13 - Non Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable

530869

Fluorochem

2-((3-AMINOPROPYL)AMINO)ETHANETHIOL 2HCL

90%

11792元/250mg; 29458元/1g;

咨询

基本信息

CAS Number	14653-77-1
MDL Number	MFCD00460339

CAS号首数字顺序排列： 1 2 3 4 5 6 7 8 9