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CAS: 146-77-0
分子式: C10H12ClN5O4
分子量: 301.68
熔点: 162 °C
中文名称: 
2-氯腺嘌呤核苷
2-氯腺苷
英文名称: 
2-chloroadenosine
2-chloro-adenosin
cl-ado
2-chloroadenosine(2-cl-ado)
推荐供应商
货号品牌产品名称规格包装、参考价格详情
C804434MACKLIN2-氯腺嘌呤核苷99%29元/250mg;   34元/1g;   150元/5g;   735元/25g;   展开
储存:2~8°C
状态:白色粉末
折射率:-50 ° (C=0.1, H2O)
C2192TCI2-Chloroadenosine>98.0%(T)(HPLC)190元/100MG;   690元/1G;   展开

基本信息

纯度/分析方法>98.0%(T)(HPLC)
分子式/分子量C10H12ClN5O4 = 301.69
外观与形状(20℃)固体
Reaxys-RN43957
PubChem物质ID87559667
SDBS (AIST Spectral DB)51987
MDL编号MFCD00005734

技术规格

AppearanceWhite to Almost white powder to crystal
Purity(HPLC)min. 98.0 area%
Purity(Nonaqueous Titration)min. 98.0 %(calcd.on anh.substance)
Specific rotation [a]20/D-46.0 to -53.0 deg(C=0.1, H2O)
Watermax. 7.0 %

物性(参考值)

熔点162 ℃
比旋光度 [α]D-50° (C=0.1,H2O)

相关法规

RTECS#AU7357550
489867J&K2-Chloroadenosine99%195元/250MG;   644元/1G;   展开

基本信息

分子式C10H12ClN5O4
分子量301.69
比旋光度([α]20D)-53° to -46° (C=1, H2O)
MDL编码MFCD00005734
Beilstein43957

安全信息

防范说明P262
WGK3
RTECSAU7357550
Y10250Alfa Aesar2-Chloroadenosine168元/1g;   506元/5g;   854元/10g;   2033元/25g;   展开

基本信息

分子量
301.69

C5134Sigma-Aldrich2-Chloroadenosine1369.7元/10 MG;   4576.56元/50 MG;   12594.8元/250 MG;   38883.1元/1 G;   展开

产品说明

应用

2-氯腺苷已用于:

  • 作为小鼠背侧海马体(DH)和腹侧海马体(VH)腺苷受体(A1R)的激动剂
  • 作为人工脑脊液(aCSF)组分,用于海马体切片的电生理实验
  • 作为固相萃取-液相色谱-串联质谱法(XLC-MS/MS)的内标,用于定量分析来自轴突裂解物和背根神经节(DRG)神经元的相应代谢物

包装

10 mg in glass bottle
50, 250 mg in poly bottle
1 g in poly bottle

生化/生理作用

2-氯腺苷是一种腺苷的类似物。它是腺苷A1受体激动剂。它可能具有抗氧化性能。

其他说明

斯克里普斯代谢组学和质谱技术中心独立生成的串联质谱数据可在PDF C5134.pdf 中查看或下载。斯克里普斯代谢物组学和质谱技术中心的METLIN代谢物数据库中有测试代谢物。要了解更多信息,请访问sigma.com/metlin。

基本信息

经验(实验)分子式C10H12ClN5O4
分子量301.69
Beilstein43957
EC 号205-678-3
MDL编号MFCD00005734
PubChem化学物质编号24277688
NACRESNA.77

产品性质

质量水平200
SMILES stringNc1nc(Cl)nc2n(cnc12)[C@@H]3O[C@H](CO)[C@@H](O)[C@H]3O
InChI1S/C10H12ClN5O4/c11-10-14-7(12)4-8(15-10)16(2-13-4)9-6(19)5(18)3(1-17)20-9/h2-3,5-6,9,17-19H,1H2,(H2,12,14,15)/t3-,5-,6-,9-/m1/s1
InChI keyBIXYYZIIJIXVFW-UUOKFMHZSA-N
Gene Informationhuman ... ADORA1(134), ADORA3(140)
rat ... Adora1(29290), Adora2a(25369), Adora3(25370)

安全信息

储存分类代码13 - Non Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
个人防护装备Eyeshields, Gloves, type N95 (US)
M04084Fluorochem2-Chloroadenosine95%462元/1g;   1408元/5g;   2354元/10g;   4400元/25g;   展开

基本信息

CAS Number146-77-0
MDL NumberMFCD00005734

安全信息

图形或危害标志
危险性说明 H302: Harmful if swallowed.
H315: Causes skin irritation.
H319: Causes serious eye irritation.
H332: Harmful if inhaled.
H335: May cause respiratory irritation.
防范说明 P233: Keep container tightly closed.
P260: Do not breathe .
P261: Avoid breathing .
P264: Wash hands thoroughly after handling.
P270: Do not eat, drink or smoke when using this product.
P271: Use only outdoors or in a well-ventilated area.
P280: Wear .
P301 + P312: IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell.
P302 + P352: IF ON SKIN: Wash with plenty of soap and water.
P304: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing..
P304 + P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P312: Call a POISON CENTER or doctor/physician if you feel unwell.
P321: Specific treatment (see relevant procedures. on this label).
P330: Rinse mouth.
P332 + P313: If skin irritation occurs: Get medical advice/ attention.
P337 + P313: If eye irritation persists: Get medical advice/attention.
P340: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P362: Take off contaminated clothing and wash before reuse.
P403: Store in a well-ventilated place.
P403 + P233: Store in a well-ventilated place. Keep container tightly closed.
P405: Store locked up.
P501: Dispose of contents/container to in accordance with local regulation .
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