CAS 144337-18-8; ym 26734

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CAS:

144337-18-8

分子式:

C₄₅H₆₂O₈

分子量:

731

英文名称:

ym 26734

用途:

YM-26734 is a derivative of a compound isolated from the fruit of H. amygdaline that competitively inhibits rabbit platelet sPLA2 with an IC50 value of 85 nM.

推荐供应商

货号

品牌

产品名称

规格

包装、参考价格

Y911042

MACKLIN

YM-26734

98%

504元/1mg; 1898元/5mg;

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储存：-20°C，密闭，干燥
状态：白色到米黄色粉末

SML1226

Sigma-Aldrich

YM-26734

≥95% (HPLC)

1399.43元/5 MG; 5643.95元/25 MG;

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产品说明

包装

5, 25 mg in glass bottle

生化/生理作用

YM-26734 is a competitive inhibitor of the secreted (Group II) form of phospholipase A2. The IC₅₀against rabbit platelet derived sPLA2 is 85 nM. YM-26734 is active against, but less potent for group I (pancreatic) sPLA2 (porcine pancreatic enzyme IC₅₀ = 7 μM), and does not inhibit intracellular PLA2 isoforms.
YM-26734 is a natural product analog and a derivative of YM-26567-1, which is found in the fruit of Horsfieldia amygdaline. It exhibits a broad inhibitory spectrum towards different sPLA2s.

基本信息

经验(实验)分子式	C₄₅H₆₂O₈
分子量	730.97
MDL编号	MFCD00918068
PubChem化学物质编号	329825731
NACRES	NA.77

产品性质

质量水平	100
测定	≥95% (HPLC)
形式	powder
颜色	white to beige
溶解性	DMSO: 20 mg/mL, clear
储存温度	−20℃
SMILES string	OC1=C(C2CC(C3=CC=C(O)C=C3)OC4=C2C=CC(O)=C4)C(O)=C(C(CCCCCCCCCCC)=O)C(O)=C1C(CCCCCCCCCCC)=O
InChI	1S/C45H62O8/c1-3-5-7-9-11-13-15-17-19-21-36(48)41-43(50)40(44(51)42(45(41)52)37(49)22-20-18-16-14-12-10-8-6-4-2)35-30-38(31-23-25-32(46)26-24-31)53-39-29-33(47)27-28-34(35)39/h23-29,35,38,46-47,50-52H,3-22,30H2,1-2H3
InChI key	CEJAYJCUSZHYDS-UHFFFAOYSA-N

安全信息

储存分类代码	13 - Non Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable

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