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CAS: 141-82-2
分子式: C3H4O4
分子量: 104.06
沸点: 140℃(分解)
熔点: 132-135 °C (dec.)(lit.)
中文名称: 
甜菜酸
甲烷二羧酸
丙烷二羧酸
丙二酸
胡萝卜酸
缩苹果酸
英文名称: 
Malonic acid
Propanedioic acid
Carboxyacetic acid
dicarboxymethane
kyselina malonova
methanedicarboxylic acid
usaf ek-695
Malonsαure(α-Form)
Methane dicardonic acid
Methanadicarboxylic acid
Malonate standard for IC
malonicacid
展开更多英文名
性质描述: 白色结晶。熔点135.6℃(少量升华),沸点140℃(分解),相对密度1.619(16/4℃)。1g该品可溶于0.65ml水、2ml乙醇、1.1ml甲醇、3ml丙醇、13ml乙醚、7ml吡啶。在真空中升华。脱水后生成丙二酸酐,脱羧生成乙酸。
生产方法: 工业上常用水解氰乙酸或丙二酸二乙酯的方法制丙二酸。由于丙二酸本身不很稳定,它在有机合成中是通过丙二酸二乙酯进行的。丙二酸以钙盐形式存在于甜菜根中,甜菜制糖的深缩罐里沉积的水垢即丙二酸钙。丙二酸是一种新陈代谢的中间体,其衍生物具有生物活性,丙二酸酯尤其是丙二酸二乙酯与乙酰乙酸乙酯一样,是有机合成极为重要的中间体。制备丙二酸及其衍生物的中间体是氰乙酸,氰乙酸经水解转化成游离丙二酸,一般不加分离,直接进行酯化。通常转化为二乙酯,而游离丙二酸通常由丙二酸二乙酯水解制得。
用途: 丙二酸及其酯主要用于香料、粘合剂、树脂添加剂、医药中间体、电镀抛光剂、爆炸控制剂、热焊接助熔添加剂等方面。在医药工业中用于生产鲁米那、巴比妥、维生素B1、维生素B2、维生素B6、苯基保泰松、氨基酸等。丙二酸用作铝表面处理剂,由于加热分解时只生成水和二氧化碳,因而没有污染问题。在这一点上,与过去采用的甲酸等酸型处理剂相比,具有很大的优点。
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M707999MACKLIN丙二酸溶液50g/L in H2O89元/100ml;   270元/500ml;   展开
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M813041MACKLIN丙二酸98%32元/100g;   118元/500g;   496元/2.5kg;   1380元/10kg;   展开
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状态:白色粉末或晶体或颗粒或块状
M813040MACKLIN丙二酸试剂级, 99.5%78元/100g;   258元/500g;   806元/2.5kg;   2196元/10kg;   3065元/12X500g;   展开
储存:室温
状态:白色粉末或晶体或颗粒或块状
M0028TCIMalonic Acid>99.0%(T)105元/25G;   360元/500G;   展开

基本信息

纯度/分析方法>99.0%(T)
分子式/分子量C3H4O4 = 104.06
外观与形状(20℃)固体
Reaxys-RN1751370
PubChem物质ID87572146
SDBS (AIST Spectral DB)2569
Merck Index (14)5710
MDL编号MFCD00002707

技术规格

AppearanceWhite to Almost white powder to crystal
Purity(GC)min. 96.0 %
Purity(Neutralization titration)min. 99.0 %
Solubility in Wateralmost transparency

物性(参考值)

熔点134 ℃
水溶性可溶
在水中的溶解度73 g/l   20 ℃
溶解性(可溶于)乙醚,醇

安全信息

图形或危害标志
信号词危险
危险性说明H302 : 吞咽有害。
H315 : 造成皮肤刺激。
H318 : 造成严重眼损伤。
H335 : 可能造成呼吸道刺激。
防范说明P501 : 将内装物/容器送到批准的废物处理厂处理。
P261 : 避免吸入粉尘/烟/气体/烟雾/蒸气/喷雾。
P270 : 使用本产品时不要进食、饮水或吸烟。
P271 : 只能在室外或通风良好之处使用。
P264 : 作业后彻底清洗皮肤。
P280 : 戴防护手套/戴防护眼罩/戴防护面具。
P302 + P352 : 如皮肤沾染:用水充分清洗。
P362+P364 : 脱掉沾污的衣服,清洗后方可重新使用。
P332 + P313 : 如发生皮肤刺激:求医/就诊。
P301 + P312 + P330 : 如误吞咽:如感觉不适,呼叫急救中心/医生。漱口。
P304 + P340 + P312 : 如误吸入:将人转移到空气新鲜处,保持呼吸舒适体位。如感觉不适,呼叫急救中心/医生。
P305 + P351 + P338 + P310 : 如进入眼睛:用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出,取出隐形眼镜。继续冲洗。立即呼叫急救中心/医生。
P403 + P233 : 存放在通风良好的地方。保持容器密闭。
P405 : 存放处须加锁。

相关法规

RTECS#OO0175000
302967J&KMalonic Acid99.5%246元/100G;   1025元/500G;   展开

基本信息

分子式C3H4O4
分子量104.06
熔点132-135
闪点172
密度1.6
MDL编码MFCD00002707
Beilstein1751370
Merck14,5710
EINECS 编号205-503-0

安全信息

图形或危害标志
提示语Danger
危险说明H302
H318
防范说明P280
P305+P351+P338
WGK1
RTECSOO0175000
A11526Alfa AesarMalonic Acid99%448元/100g;   1474元/500g;   5860元/2500g;   展开

应用
Malonic acid is acts as a building block in organic synthesis. It is also useful as a precursor for polyesters and alkyd resins, which is used in coating applications, thereby protecting against UV light, corrosion and oxidation. It acts as a cross linker in the coating industry and surgical adhesive. It finds application in the production of specialty chemicals, flavors and fragrances, polymer cross linkers and pharmaceuticals.

备注
Incompatible with bases, oxidizing agents and reducing agents.

基本信息

MDL
MFCD00002707

EINECS
205-503-0

分子式
C3H4O4

分子量
104.06

熔点
132-136° dec.

闪点
157°(314°F)

密度
1.62

灵敏度
Ambient temperatures.

形态
Crystalline powder

溶解性
Soluble in cold water.

Beilstein
1751370

Merck
14,5710

GHS危害和防范说明

GHS符号

Hazard Statements
H302-H315-H318-H335
Harmful if swallowed.Causes skin irritation.Causes serious eye damage.May cause respiratory irritation.

Precautionary Statements
P261-P280a-P305+P351+P338-P304+P340-P405-P501a
Avoid breathing dust/fume/gas/mist/vapours/spray.Wear protective gloves and eye/face protection.IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing.Store locked up.Dispose of contents/container in accordance with local/regional/national/international regulations.

安全信息

危险类别
22-37/38-41
Harmful if swallowed.Irritating to respiratory system and skin.Risk of serious damage to eyes.

安全等级
26-36/37/39-60
In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.Wear suitable protective clothing, gloves and eye/face protection.This material and its container must be disposed of as hazardous waste

欧盟危险品标志

RTECS
OO0175000

TSCA

031715Alfa AesarMalonic AcidReagent Grade, 99.5+%434元/100g;   2002元/500g;   7530元/2.5kg;   展开

应用
Malonic acid is used to prepare barbiturates. Its derivative diethylmalonate is used in Knoevenagel condensation reactions as well as reacts with acetone to form Meldrum's acid. It is used to control acidity, preservative additive for foods and as an excipient in pharmaceutical formulation. It acts as a precursor to polyesters and as an active component in alkyd resins. Further, it is used as a building block in chemical synthesis. In addition to this, it is used to prepare starch-based resin.

备注
Incompatible with oxidizing agents, reducing agents and bases.

基本信息

MDL
MFCD00002707

EINECS
205-503-0

分子式
C3H4O4

分子量
104.06

熔点
132-136° dec.

闪点
157°(314°F)

密度
1.62

灵敏度
Ambient temperatures.

形态
Crystalline

溶解性
Soluble in water, sodium hydroxide and alcohol. Slightly soluble in pyridine and ether.

Beilstein
1751370

Merck
14,5710

GHS危害和防范说明

GHS符号

Hazard Statements
H302-H315-H318-H335
Harmful if swallowed.Causes skin irritation.Causes serious eye damage.May cause respiratory irritation.

Precautionary Statements
P261-P280a-P305+P351+P338-P304+P340-P405-P501a
Avoid breathing dust/fume/gas/mist/vapours/spray.Wear protective gloves and eye/face protection.IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing.Store locked up.Dispose of contents/container in accordance with local/regional/national/international regulations.

安全信息

危险类别
22-37/38-41
Harmful if swallowed.Irritating to respiratory system and skin.Risk of serious damage to eyes.

安全等级
26-36/37/39-60
In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.Wear suitable protective clothing, gloves and eye/face protection.This material and its container must be disposed of as hazardous waste

欧盟危险品标志

RTECS
OO8175000

TSCA

C12526Alfa AesarMalonic Acid99%1444元/250g;   3995元/1kg;   11357元/5kg;   展开

基本信息

Ref#
12526

MDL
2707

分子式
C3 H4 O4

分子量
104.06

闪点
172

形态
Crystalline

792535Sigma-AldrichMalonic Acidanhydrous, free-flowing, Redi-Dri, ReagentPlus®, 99%608.39元/100 G;   2190.79元/500 G;   2289.38元/1 KG;   4192.45元/2.5 KG;   展开

产品说明

包装

1, 2.5 kg in poly bottle
100, 500 g in poly bottle
1, 2.5 kg in poly bottle
100, 500 g in poly bottle

法律信息

ReagentPlus is a registered trademark of sigma-aldrich Co. LLC
Redi-Dri is a trademark of sigma-aldrich Co. LLC

基本信息

线性分子式CH2(COOH)2
分子量104.06
Beilstein1751370
EC 号205-503-0
MDL编号MFCD00002707
PubChem化学物质编号329768342
NACRESNA.21

产品性质

质量水平100
等级anhydrous
产品线ReagentPlus®
Redi-Dri
测定99%
形式powder
质量free-flowing
mp132-135 ℃ (dec.) (lit.)
溶解性1 M NaOH: 100 mg/mL, clear to slightly hazy, colorless to faintly yellow
SMILES stringOC(=O)CC(O)=O
InChI1S/C3H4O4/c4-2(5)1-3(6)7/h1H2,(H,4,5)(H,6,7)
InChI keyOFOBLEOULBTSOW-UHFFFAOYSA-N

安全信息

象形图GHS05
警示用语:Danger
危险声明H318
预防措施声明P280 - P305 + P351 + P338
危险分类Eye Dam. 1
储存分类代码13 - Non Combustible Solids
WGKWGK 1
闪点(F)314.6 °F
闪点(C)157 ℃
M1296Sigma-AldrichMalonic AcidReagentPlus®, 99%277.32元/5 G;   657.98元/100 G;   2039.15元/500 G;   9685.17元/2.5 KG;   11139.3元/5 KG;   展开

产品说明

一般描述

丙二酸(MA),也称为丙二酸,是一种二羧酸。丙二酸的晶体在室温下是三斜晶系。已经研究了铈(IV)在硫酸溶液中氧化丙二酸。已经描述了在二氧化钛(TiO2)的水悬浮液中光催化分解丙二酸的反应动力学。

应用

丙二酸可用作玉米淀粉和马铃薯淀粉之间的交联剂,以改善其机械性能。

包装

5, 100, 500 g in poly bottle
2.5 kg in poly bottle
5 kg in poly drum

其他说明

参见Redi-Dri 产品清单792535

法律信息

ReagentPlus is a registered trademark of sigma-aldrich Co. LLC
Redi-Dri is a trademark of sigma-aldrich Co. LLC

基本信息

线性分子式CH2(COOH)2
分子量104.06
Beilstein1751370
EC 号205-503-0
MDL编号MFCD00002707
PubChem化学物质编号24896631

产品性质

质量水平200
产品线ReagentPlus®
测定99%
形式chunks
granular
powder or crystals
mp132-135 ℃ (dec.) (lit.)
溶解性1 M NaOH: 100 mg/mL, clear to slightly hazy, colorless to faintly yellow
SMILES stringOC(=O)CC(O)=O
InChI1S/C3H4O4/c4-2(5)1-3(6)7/h1H2,(H,4,5)(H,6,7)
InChI keyOFOBLEOULBTSOW-UHFFFAOYSA-N
Gene Informationhuman ... SRC(6714)

安全信息

象形图GHS05
警示用语:Danger
危险声明H318
预防措施声明P280 - P305 + P351 + P338
危险分类Eye Dam. 1
储存分类代码13 - Non Combustible Solids
WGKWGK 1
闪点(F)314.6 °F
闪点(C)157 ℃
个人防护装备dust mask type N95 (US), Eyeshields, Faceshields, Gloves
68714SupelcoMalonic Acidcertified reference material, TraceCERT®, Manufactured by: Sigma-Aldrich Production GmbH, Switzerland1750.6元/100 mg;   展开

产品说明

一般描述

This certified reference material (CRM) is produced and certified in accordance with ISO/IEC 17025 and ISO 17034. This CRM is traceable to primary material from an NMI, e.g. NIST or NMIJ.
Certified content by quantitative NMR incl. uncertainty and expiry date are given on the certificate.
Download your certificate at: http://www.sigma-aldrich.com.

应用

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

包装

Bottomless glass bottle. Contents are inside inserted fused cone.

法律信息

TraceCERT is a registered trademark of sigma-aldrich Co. LLC

基本信息

线性分子式CH2(COOH)2
分子量104.06
Beilstein1751370
EC 号205-503-0
MDL编号MFCD00002707
PubChem化学物质编号329761103
NACRESNA.24

产品性质

质量水平300
等级certified reference material
TraceCERT®
保质期limited shelf life, expiry date on the label
technique(s)HPLC: suitable
gas chromatography (GC): suitable
mp132-135 ℃ (dec.) (lit.)
application(s)cleaning products
cosmetics
flavors and fragrances
food and beverages
personal care
格式neat
SMILES stringOC(=O)CC(O)=O
InChI1S/C3H4O4/c4-2(5)1-3(6)7/h1H2,(H,4,5)(H,6,7)
InChI keyOFOBLEOULBTSOW-UHFFFAOYSA-N

安全信息

象形图GHS05
警示用语:Danger
危险声明H318
预防措施声明P280 - P305 + P351 + P338
危险分类Eye Dam. 1
储存分类代码13 - Non Combustible Solids
WGKWGK 1
闪点(F)314.6 °F
闪点(C)157 ℃
939788AmethystMalonic Acid98%, 用于合成63元/100G;   250元/500G;   展开

基本信息

分子式C3H4O4
分子量104.06
熔点132-135
闪点172
密度1.6
MDL编码MFCD00002707
Beilstein1751370
Merck14,5710
EINECS 编号205-503-0

安全信息

图形或危害标志
提示语Danger
危险说明H302
H318
防范说明P280
P305+P351+P338
WGK1
RTECSOO0175000
020000FluorochemMalonic Acid95%330元/100g;   770元/500g;   1210元/1kg;   展开

基本信息

CAS Number141-82-2
MDL NumberMFCD00002707
Melting Point135-140℃

安全信息

图形或危害标志
危险性说明 H319: Causes serious eye irritation.
防范说明 P264: Wash hands thoroughly after handling.
P280: Wear .
P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P337 + P313: If eye irritation persists: Get medical advice/attention.
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