CAS 140898-91-5; 5-氨基酮戊酸己酯盐酸盐; hexaminolevulinate hydrochloride

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货号

品牌

产品名称

规格

包装、参考价格

H794322

MACKLIN

5-氨基酮戊酸己酯盐酸盐

10mM in DMSO

186元/1ml;

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储存：-20°C

H858463

MACKLIN

5-氨基酮戊酸己酯盐酸盐

98%

120元/100mg; 390元/500mg; 718元/1g; 2154元/5g;

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储存：室温,干燥
状态：白色到米黄色固体

SML1637

Sigma-Aldrich

Hexaminolevulinate hydrochloride

≥98% (HPLC)

1117.23元/10 MG; 4498.97元/50 MG;

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产品说明

包装

10, 50 mg in glass bottle

生化/生理作用

Hexaminolevulinate (HAL) hydrochloride is a hexyl ester of 5-Aminolevulinic acid (ALA), a precursor to porphyrins including the photosensitizer protoporphyrin IX (PPIX). Hexaminolevulinate is more lipophilic than ALA, and is 50–100 times more efficient than ALA at inducing PpIX, which accumulates preferentially in neoplastic cells. Hexaminolevulinate administration followed by light activation has been used for fluorescence cystoscopy to enhance detection of bladder cancer, in particular carcinoma in situ (CIS). Hexaminolevulinate is also being studied for use in cancer photodynamic therapy. Hexaminolevulinate followed by irradiation produced DNA oxidative damage and apoptosis.

基本信息

经验(实验)分子式	C₁₁H₂₁NO₃ · HCl
分子量	251.75
MDL编号	MFCD03695491
PubChem化学物质编号	329825978

产品性质

质量水平	100
测定	≥98% (HPLC)
形式	powder
颜色	white to beige
溶解性	H₂O: 20 mg/mL, clear
储存温度	room temp
SMILES string	CCCCCCOC(CCC(CN)=O)=O.[H]Cl
InChI	1S/C11H21NO3.ClH/c1-2-3-4-5-8-15-11(14)7-6-10(13)9-12;/h2-9,12H2,1H3;1H
InChI key	LZYXPFZBAZTOCH-UHFFFAOYSA-N

安全信息

储存分类代码	13 - Non Combustible Solids
WGK	WGK 3

222389

Fluorochem

Hexyl 5-amino-4-oxopentanoate hydrochloride

95%

1562元/1g; 5390元/5g; 25388元/25g;

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基本信息

CAS Number	140898-91-5
MDL Number	MFCD03695491
Melting Point	138-142℃

安全信息

图形或危害标志
危险性说明	H315: Causes skin irritation. H319: Causes serious eye irritation. H335: May cause respiratory irritation.
防范说明	P233: Keep container tightly closed. P260: Do not breathe . P261: Avoid breathing . P264: Wash hands thoroughly after handling. P271: Use only outdoors or in a well-ventilated area. P280: Wear . P302 + P352: IF ON SKIN: Wash with plenty of soap and water. P304: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.. P304 + P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing. P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P312: Call a POISON CENTER or doctor/physician if you feel unwell. P321: Specific treatment (see relevant procedures. on this label). P332 + P313: If skin irritation occurs: Get medical advice/ attention. P337 + P313: If eye irritation persists: Get medical advice/attention. P340: Remove victim to fresh air and keep at rest in a position comfortable for breathing. P362: Take off contaminated clothing and wash before reuse. P403: Store in a well-ventilated place. P403 + P233: Store in a well-ventilated place. Keep container tightly closed. P405: Store locked up. P501: Dispose of contents/container to in accordance with local regulation .