| CAS: | 140651-18-9 | ||
| 分子式: | C9H10N6O | ||
| 分子量: | 218.22 | ||
| 英文名称: |
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| 货号 | 品牌 | 产品名称 | 规格 | 包装、参考价格 | |||||||||||||||||||||||||||||||||
| C993412 | MACKLIN | CAY10574 | ≥99% | 621元/5mg; 1242元/10mg; 5188元/50mg; | 咨询 | ||||||||||||||||||||||||||||||||
储存：2-8°C, 避光 | |||||||||||||||||||||||||||||||||||||
| 238811 | Sigma-Aldrich | Cdk9 Inhibitor II-CAS 140651-18-9-Calbiochem | The Cdk9 Inhibitor II, also referenced under CAS 140651-18-9, controls the biological activity of Cdk9. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation appl | 3614.11元/5 MG; | 咨询 | ||||||||||||||||||||||||||||||||
产品说明 一般描述 A cell-permeable azo-pyrazole compound that acts as a potent, ATP-competitive, and Cdk9-selective inhibitor (IC50 = 350 nM, using Cdk9/T1). It inhibits Cdk1/B, Cdk2/E, Cdk2/A, Cdk4/D1, Cdk7/H, and p70S6K only at much higher concentrations (IC50 = 44, 20, 69, 13.5, 26, and 10 µM, respectively) and shows little or no activity against eight other commonly studied kinases even at concentrations as high as 10 µM. Shown to exhibit antiproliferative activity in human tumor cell lines. 包装 5 mg in Plastic ampoule 生化/生理作用 Cell permeable: yes 警告 Toxicity: Irritant (B) 其他说明 Krystof, V., et al. 2006. J. Med. Chem.49, 6500. 法律信息 CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany 基本信息
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