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CAS: 140-64-7
分子式: C19H24N4O2·2C2H6O4S
分子量: 592.68
熔点: 188-194 °C
中文名称: 
喷他脒 羟乙基磺酸盐
4,4′-(pentamethylenedioxy)dibenzamidine bis(2-hydroxyethanesulfonate)
4,4′-二苯甲脒双
1,5-双( p -脒基苯氧基)戊烷双(2-羟乙磺酸盐)
英文名称: 
pentamidine diisetionate
1,5-bis(p-amidinophenoxy)pentane bis(2-hydroxyethanesulfonate salt)
pentamidine isethionate salt
推荐供应商
货号品牌产品名称规格包装、参考价格详情
P793619MACKLIN羟乙磺酸喷他眯10mM in DMSO1180元/1ml;   展开
储存:-20°C
P859580MACKLIN羟乙磺酸喷他眯97%105元/250mg;   317元/1g;   展开
储存:-20°C
状态:固体
C46186Alfa AesarPentamidine isethionate salt97%5888元/1g;   展开

基本信息

Ref#
46186

分子式
C19H24N4O2.2C2H6O4S

分子量
295.72

GHS危害和防范说明

GHS符号

Hazard Statements
H315 H317 H319 H335

Precautionary Statements
P302+P352 P337+P313 P304+P340 P312 P280 P332+P313

P0405000Pentamidine diisetionateEuropean Pharmacopoeia (EP) Reference Standard1268.28元/ ;   展开

产品说明

一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

包装

Unit quantity: 30 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

注意

Please find SDS provided by EDQM here..

其他说明

Sales restrictions may apply.

基本信息

线性分子式CH2[CH2CH2OC6H4C(=NH)NH2]2·2HOCH2CH2SO3H
分子量592.68
MDL编号MFCD00079213
PubChem化学物质编号329820036
NACRESNA.24

产品性质

等级pharmaceutical primary standard
manufacturer/tradenameEDQM
mp188-194 ℃ (lit.)
application(s)pharmaceutical (small molecule)
格式neat
储存温度2-8℃
SMILES stringOCCS(O)(=O)=O.OCCS(O)(=O)=O.NC(=N)c1ccc(OCCCCCOc2ccc(cc2)C(N)=N)cc1
InChI1S/C19H24N4O2.2C2H6O4S/c20-18(21)14-4-8-16(9-5-14)24-12-2-1-3-13-25-17-10-6-15(7-11-17)19(22)23;2*3-1-2-7(4,5)6/h4-11H,1-3,12-13H2,(H3,20,21)(H3,22,23);2*3H,1-2H2,(H,4,5,6)
InChI keyYBVNFKZSMZGRAD-UHFFFAOYSA-N

安全信息

象形图GHS07
警示用语:Warning
危险声明H315 - H317 - H319 - H335
预防措施声明P280 - P302 + P352 - P305 + P351 + P338
危险分类Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3
靶器官Respiratory system
储存分类代码11 - Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
P0547Sigma-AldrichPentamidine isethionate saltpowder475.35元/100 MG;   534.05元/25 MG;   855.85元/250 MG;   2038.2元/1 G;   展开

产品说明

应用

异硫氰酸喷他脒盐已用于:

  • 作为抗利什曼原虫、抗疟原虫和细胞毒性试验的阳性对照
  • 作为原型化合物,分析抑制剂对人快速延迟性整流性相关基因 (HERG) K + 通道转运的影响
  • 作为前鞭毛体中的抗利什曼原虫药物

卡氏肺囊虫抗菌药

包装

25 mg in poly bottle
1 g in glass bottle
100, 250 mg in glass bottle

生化/生理作用

羟乙基喷他脒作为利什曼病的二线药物。
具有神经保护作用;抑制脑内组成型一氧化氮合酶;NMDA 谷氨酸受体拮抗剂。

特点和优势

该化合物由 Celgene 开发。要浏览其他制药公司开发的化合物列表批准的药物/候选药物的列表, 点击这里 。

基本信息

线性分子式CH2[CH2CH2OC6H4C(=NH)NH2]2·2HOCH2CH2SO3H
分子量592.68
EC 号205-424-1
MDL编号MFCD00079213
PubChem化学物质编号24277999
NACRESNA.77

产品性质

形式powder
质量水平100
mp188-194 ℃ (lit.)
作用机制enzyme | inhibits
抗生素抗菌谱fungi
创始人Celgene
储存温度−20℃
SMILES stringOCCS(O)(=O)=O.OCCS(O)(=O)=O.NC(=N)c1ccc(OCCCCCOc2ccc(cc2)C(N)=N)cc1
InChI1S/C19H24N4O2.2C2H6O4S/c20-18(21)14-4-8-16(9-5-14)24-12-2-1-3-13-25-17-10-6-15(7-11-17)19(22)23;2*3-1-2-7(4,5)6/h4-11H,1-3,12-13H2,(H3,20,21)(H3,22,23);2*3H,1-2H2,(H,4,5,6)
InChI keyYBVNFKZSMZGRAD-UHFFFAOYSA-N
Gene Informationhuman ... GRIN1(2902), GRIN2A(2903), GRIN2B(2904), GRIN2C(2905), GRIN2D(2906), GRINA(2907), NOS1(4842), NOS2(4843), NOS2B(201288), NOS2C(645740), NOS3(4846)

安全信息

象形图GHS07
警示用语:Warning
危险声明H315 - H317 - H319 - H335
预防措施声明P280 - P302 + P352 - P305 + P351 + P338
危险分类Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3
靶器官Respiratory system
储存分类代码11 - Combustible Solids
WGKWGK 3
1504900USPPentamidine isethionateUnited States Pharmacopeia (USP) Reference Standard3231.47元/200 MG;   展开

产品说明

一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

分析说明

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

其他说明

USP issued SDS can be found here.
Sales restrictions may apply.

基本信息

线性分子式CH2[CH2CH2OC6H4C(=NH)NH2]2·2HOCH2CH2SO3H
分子量592.68
MDL编号MFCD00079213
PubChem化学物质编号329750690
NACRESNA.24

产品性质

等级pharmaceutical primary standard
manufacturer/tradenameUSP
mp188-194 ℃ (lit.)
application(s)pharmaceutical (small molecule)
格式neat
SMILES stringOCCS(O)(=O)=O.OCCS(O)(=O)=O.NC(=N)c1ccc(OCCCCCOc2ccc(cc2)C(N)=N)cc1
InChI1S/C19H24N4O2.2C2H6O4S/c20-18(21)14-4-8-16(9-5-14)24-12-2-1-3-13-25-17-10-6-15(7-11-17)19(22)23;2*3-1-2-7(4,5)6/h4-11H,1-3,12-13H2,(H3,20,21)(H3,22,23);2*3H,1-2H2,(H,4,5,6)
InChI keyYBVNFKZSMZGRAD-UHFFFAOYSA-N

安全信息

象形图GHS07
警示用语:Warning
危险声明H315 - H317 - H319 - H335
预防措施声明P280 - P305 + P351 + P338
危险分类Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3
靶器官Respiratory system
储存分类代码13 - Non Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
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