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CAS: 140-53-4
分子式: C8H6ClN
分子量: 151.59
沸点: 265-267℃
熔点: 29-30℃
中文名称: 
4-氯苯基乙腈
4-氯苯乙腈
4-氯苄氰
对氯苯乙腈
对氰基氯苄
对氯苄氰
对氯氰苄
对氯苄基氰
英文名称: 
4-Chlorophenylacetonitrile
4-cyanobenzylchloride
chlorobenzyl cyanide
4-Chlorobenzyl cyanide
4-chloro-Benzeneacetonitrile
(p-chlorophenyl)-acetonitril
(4-chlorophenyl)acetonitrile
2-(4-chlorophenyl)acetonitrile
4-chlor-benzyl-cyanid
4-chlorobenzeneacetonitrile
4-chloro-benzeneacetonitril
p-chlorobenzyl cyanide
p-chlorophenylacetonitrile
(p-Chlorophenyl)acetonitrile
Benzeneacetonitrile,4-chloro-
展开更多英文名
性质描述: 无色至浅黄色固体。熔点27℃,沸点265-267℃,闪点110℃。溶于丙酮及乙醇。
生产方法: 由对氯氯苄与氰化钠反应而得。将对氯氯苄及新洁尔灭加入反应锅,加热至100℃,慢慢加入氰化钠水溶液,在100-104℃下反应5h(加氰化钠3h,保温2h)。然后加水溶解氯化钠,分去水层,得对氯氰苄粗品,减压蒸馏,收集160(2.66kPa)馏分得成品。收率81%以上。对氯氯苄与氰化钠在乙醇中于83-85℃回流4h,也可制得该品。工业用中间体为微黄色液体,含对氯氰苄≥90%。原料消耗定额:对氯氯苄(92%)1432kg/t、氰化钠(95%)450kg/t、新洁尔灭(90%以上)18kg/t。
用途: 药物乙胺嘧啶的中间体。用于制造对氯苯甲醇、对氯苯甲醛、对氯苯乙腈等。
推荐供应商
货号品牌产品名称规格包装、参考价格详情
C829737MACKLIN对氯苯乙腈98%25元/25g;   40元/100g;   190元/500g;   947元/2.5kg;   展开
储存:室温
状态:白色到黄色固体或液体
折射率:n20/D 1.543
C0585TCI4-Chlorobenzyl Cyanide>98.0%(GC)125元/25G;   805元/500G;   展开

基本信息

纯度/分析方法>98.0%(GC)
分子式/分子量C8H6ClN = 151.59
外观与形状(20℃)固体
Reaxys-RN971171
PubChem物质ID87565686
SDBS (AIST Spectral DB)6085
MDL编号MFCD00001918

技术规格

AppearanceWhite or Colorless to Light yellow powder to lump to clear liquid
Purity(GC)min. 98.0 %

物性(参考值)

熔点28 ℃
沸点267 ℃
水溶性可溶
在水中的溶解度550 g/l   20 ℃
溶解性(可溶于)苯,丙酮,甲苯,醇

安全信息

图形或危害标志
信号词危险
危险性说明H300 : 吞咽致命。
H315 : 造成皮肤刺激。
H319 : 造成严重眼刺激。
防范说明P501 : 将内装物/容器送到批准的废物处理厂处理。
P270 : 使用本产品时不要进食、饮水或吸烟。
P264 : 作业后彻底清洗皮肤。
P280 : 戴防护手套/戴防护眼罩/戴防护面具。
P302 + P352 : 如皮肤沾染:用水充分清洗。
P337 + P313 : 如仍觉眼刺激:求医/就诊。
P305 + P351 + P338 : 如进入眼睛:用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出,取出隐形眼镜。继续冲洗。
P362+P364 : 脱掉沾污的衣服,清洗后方可重新使用。
P332 + P313 : 如发生皮肤刺激:求医/就诊。
P301 + P310 + P330 : 如误吞咽:立即呼叫急救中心/医生。漱口。
P405 : 存放处须加锁。

相关法规

RTECS#AL8250000

运输信息

UN编号UN3439
类别6.1
包装类别 II
监管条件代码(*)
478738J&K4-Chlorobenzyl Cyanide98%115元/25G;   232元/100G;   855元/500G;   展开

基本信息

分子式C8H6ClN
分子量151.59
熔点25-28
沸点265-267
闪点134
密度1.19
MDL编码MFCD00001918
Beilstein971171
EINECS 编号205-418-9

安全信息

图形或危害标志
提示语Danger
危险说明H301
H311
H315
H319
H331
H335
防范说明P261
P280
P301+P310
P305+P351+P338
P311
UN号码2811
危险分类6.1
包装等级III
WGK3
RTECSAL8250000
TSCA
A15295Alfa Aesar4-Chlorophenylacetonitrile98+%277元/100g;   910元/500g;   展开

基本信息

MDL
MFCD00001918

EINECS
205-418-9

分子式
C8H6ClN

分子量
151.60

熔点
28-31°

沸点
141-143°/11mm

闪点
134°(273°F)

密度
1.190

折射率
1.5430

形态
Solid

Beilstein
971171

GHS危害和防范说明

GHS符号

Hazard Statements
H300-H311-H331-H315-H319-H335
Fatal if swallowed.Toxic in contact with skin.Toxic if inhaled.Causes skin irritation.Causes serious eye irritation.May cause respiratory irritation.

Precautionary Statements
P280h-P305+P351+P338-P309-P310
Wear protective gloves/clothing.IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.IF exposed or if you feel unwell:Immediately call a POISON CENTER or doctor/physician.

安全信息

危险等级
6.1

包装组
II

危险类别
23/24/25-36/37/38
Toxic by inhalation, in contact with skin and if swallowed.Irritating to eyes, respiratory system and skin.

安全等级
4-9-20-26-27-36/37-45-60
Keep away from living quarters.Keep container in a well-ventilated place.When using do not eat or drink.In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.Take off immediately all contaminated clothing.Wear suitable protective clothing and gloves.In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).This material and its container must be disposed of as hazardous waste

RTECS
AL8250000

TSCA

C10881Alfa Aesar4-Chlorobenzyl Cyanide98+%572元/100g;   602元/5g;   2721元/500g;   1282元/250g;   展开

基本信息

Ref#
10881

MDL
1918

分子式
C8 H6 Cl N

分子量
151.6

闪点
133

形态
White to pale yellow solid

安全信息

危险等级
6.1

包装组
II

C28006Sigma-Aldrich(4-Chlorophenyl)acetonitrile96%454.57元/100 G;   展开

基本信息

线性分子式ClC6H4CH2CN
分子量151.59
Beilstein971171
EC 号205-418-9
MDL编号MFCD00001918
PubChem化学物质编号24892534
NACRESNA.22

产品性质

质量水平100
测定96%
bp265-267 ℃ (lit.)
mp25-28 ℃ (lit.)
密度1.19 g/mL at 20 ℃ (lit.)
SMILES stringClc1ccc(CC#N)cc1
InChI1S/C8H6ClN/c9-8-3-1-7(2-4-8)5-6-10/h1-4H,5H2
InChI keyIVYMIRMKXZAHRV-UHFFFAOYSA-N

安全信息

象形图GHS06
警示用语:Danger
危险声明H300 - H315 - H319 - H335
预防措施声明P301 + P310 + P330 - P302 + P352 - P305 + P351 + P338
危险分类Acute Tox. 2 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官Respiratory system
储存分类代码6.1A - Combustible, acute toxic Cat. 1 and 2 / very toxic hazardous materials
WGKWGK 3
闪点(F)271.4 °F
闪点(C)133 ℃
个人防护装备Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
079011Fluorochem4-Chlorobenzyl Cyanide95%330元/100g;   展开

基本信息

CAS Number140-53-4
MDL NumberMFCD00001918
Boiling Point265-267℃
Melting Point25-28℃
Density1.19

安全信息

图形或危害标志
危险性说明 H301: Toxic if swallowed.
H311: Toxic in contact with skin.
H331: Toxic if inhaled.
防范说明 P260: Do not breathe .
P264: Wash hands thoroughly after handling.
P270: Do not eat, drink or smoke when using this product.
P271: Use only outdoors or in a well-ventilated area.
P280: Wear .
P301 + P310: IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P302 + P352: IF ON SKIN: Wash with plenty of soap and water.
P304 + P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P311: Call a POISON CENTER or doctor/physician.
P312: Call a POISON CENTER or doctor/physician if you feel unwell.
P321: Specific treatment (see . on this label).
P322: Specific measures (see . on this label).
P330: Rinse mouth.
P361: Remove/Take off immediately all contaminated clothing.
P363: Wash contaminated clothing before reuse.
P403 + P233: Store in a well-ventilated place. Keep container tightly closed.
P405: Store locked up.
P501: Dispose of contents/container to local regulations.
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