| CAS: | 1309976-62-2 | ||
| 分子式: | C18H16ClFN2O | ||
| 分子量: | 330.78 | ||
| 英文名称: |
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| 货号 | 品牌 | 产品名称 | 规格 | 包装、参考价格 | |||||||||||||||||||||||||||||||||
| V969484 | MACKLIN | VU 0360172 盐酸盐 | 98% | 781元/5mg; | 咨询 | ||||||||||||||||||||||||||||||||
储存：-20°C | |||||||||||||||||||||||||||||||||||||
| SML3230 | Sigma-Aldrich | VU0360172 hydrochloride | ≥98% (HPLC) | 780.67元/; 3157.38元/; | 咨询 | ||||||||||||||||||||||||||||||||
产品说明 生化/生理作用 VU0360172 is a potent (EC50 = 16.6 nM), systemically active positive allosteric modulator (PAM) of the metabotropic glutamate receptor subtype 5 (mGlu5). It is the first orally active mGlu5 PAM to be efficacious in an in vivo preclinical antipsychotic model, producing a dose-dependent reversal of amphetamine-induced hyperlocomotion. It was also found to reduce absence seizures in WAG/Rij rats and to inhibit pain. 基本信息
产品性质
安全信息
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