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CAS: 130929-57-6
分子式: C14H15N3O5
分子量: 305.29
英文名称: 
entacapone
推荐供应商
货号品牌产品名称规格包装、参考价格详情
E794252MACKLIN恩他卡朋10mM in DMSO337元/1ml;   展开
储存:-20°C
状态:液体
E0961TCIEntacapone>98.0%(T)(HPLC)1490元/1G;   4990元/5G;   展开

基本信息

纯度/分析方法>98.0%(T)(HPLC)
分子式/分子量C14H15N3O5 = 305.29
外观与形状(20℃)固体
储存温度0-10℃
储存在惰性气体下存放于惰性气体之中
应避免的情况空气,加热
Reaxys-RN8158723
Merck Index (14)3594
MDL编号MFCD00866580

技术规格

AppearanceWhite to Yellow powder to crystal
Purity(HPLC)min. 98.0 area%
Purity(Volumetric Analysis)min. 98.0 %
Melting point160.0 to 164.0 ℃
NMRconfirm to structure

物性(参考值)

熔点162 ℃
水溶性不溶
溶解性(微溶于)甲醇
溶解度(极微溶)乙醇

相关法规

RTECS#UC6316195
374228J&KEntacapone98%1463元/50MG;   2915元/200MG;   展开

基本信息

分子式C14H15N3O5
分子量305.29
熔点156-159
存储条件Freezer -20℃

安全信息

WGK3
C46622Alfa AesarEntacapone9326元/250mg;   23393元/1g;   展开

基本信息

Ref#
46622

分子式
C14H15N3O5

分子量
534.56

Y0001249EntacaponeEuropean Pharmacopoeia (EP) Reference Standard1572.27元/ ;   展开

产品说明

一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

生化/生理作用

Entacapone is a catechol-O-methyl transferase (COMT) inhibitor. Used in treatment of Parkinson′s disease, entacapone is administered with L-DOPA to inihibit COMT from converting L-DOPA into a compound that cannot cross the blood brain barrier.

包装

Unit quantity: 160 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

注意

Please find SDS provided by EDQM here..

其他说明

Sales restrictions may apply.

基本信息

经验(实验)分子式C14H15N3O5
分子量305.29
NACRESNA.24

产品性质

等级pharmaceutical primary standard
manufacturer/tradenameEDQM
application(s)pharmaceutical (small molecule)
格式neat
储存温度2-8℃
InChI1S/C14H15N3O5/c1-3-16(4-2)14(20)10(8-15)5-9-6-11(17(21)22)13(19)12(18)7-9/h5-7,18-19H,3-4H2,1-2H3/b10-5+
InChI keyJRURYQJSLYLRLN-BJMVGYQFSA-N

安全信息

储存分类代码13 - Non Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
SML0654Sigma-AldrichEntacapone≥98% (HPLC)898.46元/10 MG;   3088.72元/50 MG;   展开

产品说明

应用

Entacapone has been used in high-performance bioaffinity chromatography.

包装

10, 50 mg in glass bottle

生化/生理作用

Entacapone acts predominantly in the intestine. It increases the bioavailability of levodopa. Levodopa is known to be associated with many complications such as motor fluctuations. COMT inhibitors have been used to overcome these adverse effects of levodopa by reducing its metabolism. Entacapone exhibits its inhibition action on COMT in the peripheral nervous system.
Entacapone is a catechol-O-methyl transferase (COMT) inhibitor. Used in treatment of Parkinson′s disease, entacapone is administered with L-DOPA to inihibit COMT from converting L-DOPA into a compound that cannot cross the blood brain barrier.

特点和优势

This compound is featured on the Dopamine and Norepinephrine Metabolism page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

基本信息

经验(实验)分子式C14H15N3O5
分子量305.29
NACRESNA.77

产品性质

质量水平100
测定≥98% (HPLC)
形式powder
颜色 white to light brown
溶解性DMSO: 20 mg/mL, clear
储存温度room temp
InChI1S/C14H15N3O5/c1-3-16(4-2)14(20)10(8-15)5-9-6-11(17(21)22)13(19)12(18)7-9/h5-7,18-19H,3-4H2,1-2H3/b10-5+
InChI keyJRURYQJSLYLRLN-BJMVGYQFSA-N

安全信息

储存分类代码13 - Non Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
1235933USPEntacaponeUnited States Pharmacopeia (USP) Reference Standard6206.86元/200 MG;   展开

产品说明

一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

生化/生理作用

Entacapone is a catechol-O-methyl transferase (COMT) inhibitor. Used in treatment of Parkinson′s disease, entacapone is administered with L-DOPA to inihibit COMT from converting L-DOPA into a compound that cannot cross the blood brain barrier.

分析说明

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

其他说明

USP issued SDS can be found here.
Sales restrictions may apply.

基本信息

经验(实验)分子式C14H15N3O5
分子量305.29
NACRESNA.24

产品性质

等级pharmaceutical primary standard
manufacturer/tradenameUSP
application(s)pharmaceutical (small molecule)
格式neat
InChI1S/C14H15N3O5/c1-3-16(4-2)14(20)10(8-15)5-9-6-11(17(21)22)13(19)12(18)7-9/h5-7,18-19H,3-4H2,1-2H3/b10-5+
InChI keyJRURYQJSLYLRLN-BJMVGYQFSA-N

安全信息

储存分类代码13 - Non Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
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