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CAS: 130-61-0
分子式: C21H27ClN2S2
分子量: 370.57
熔点: 163-167 °C
中文名称: 
盐酸硫利达嗪
硫利哌啶
甲硫达嗪
英文名称: 
10-(2-(1-methyl-2-piperidyl)ethyl)-2-(methylthio)-phenothiazin monohydrochl
10-(2-(1-methyl-2-piperidyl)ethyl)-2-methylthiophenothiazine hydrochloride
10-(2-(1-methyl-2-piperidinyl)ethyl)-2-(methylthio)-10h-phenothiazin mono
2-methylmercapto-10-(2-(n-methyl-2-piperidyl)ethyl)phenothiazine hydrochlorid
mellaril hydrochloride
melleril (tablet)
thioridazine hydrochloride
usaf sz-3
usaf sz-b
10-[2-(1-Methyl-2-piperidyl)ethyl]-2-(methylthio)-10H-phenothiazine hydrochloride
用途: 适用于急性精神分裂症、躁郁症、更年期精神病、神经性抑郁症等。
推荐供应商
货号品牌产品名称规格包装、参考价格详情
T865455MACKLIN甲硫哒嗪盐酸盐≥98%250元/1g;   1051元/5g;   展开
储存:室温
状态:白色到灰白色粉末或晶体
T792787MACKLIN甲硫哒嗪盐酸盐10mM in DMSO620元/1ml;   展开
储存:-20°C, 避光
T3102TCIThioridazine Hydrochloride>98.0%(HPLC)935元/5G;   3125元/25G;   展开

基本信息

纯度/分析方法>98.0%(HPLC)
分子式/分子量C21H26N2S2・HCl = 407.03
外观与形状(20℃)固体
应避免的情况
相关CAS RN50-52-2
Reaxys-RN4170703
PubChem物质ID354335117
Merck Index (14)9359
MDL编号MFCD00007620

技术规格

AppearanceWhite to Almost white powder to crystal
Purity(HPLC)min. 98.0 area%
Purity(with Total Nitrogen)min. 95.0 %
Melting point163.0 to 167.0 ℃

物性(参考值)

熔点165 ℃
最大吸收波长317(EtOH) nm

安全信息

图形或危害标志
信号词警告
危险性说明H302 : 吞咽有害。
H315 : 造成皮肤刺激。
H319 : 造成严重眼刺激。
H410 : 对水生生物毒性极大并具有长期持续影响。
防范说明P501 : 将内装物/容器送到批准的废物处理厂处理。
P273 : 避免释放到环境中。
P270 : 使用本产品时不要进食、饮水或吸烟。
P264 : 作业后彻底清洗皮肤。
P280 : 戴防护手套/戴防护眼罩/戴防护面具。
P302 + P352 : 如皮肤沾染:用水充分清洗。
P391 : 收集溢出物。
P337 + P313 : 如仍觉眼刺激:求医/就诊。
P305 + P351 + P338 : 如进入眼睛:用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出,取出隐形眼镜。继续冲洗。
P362+P364 : 脱掉沾污的衣服,清洗后方可重新使用。
P332 + P313 : 如发生皮肤刺激:求医/就诊。
P301 + P312 + P330 : 如误吞咽:如感觉不适,呼叫急救中心/医生。漱口。

相关法规

RTECS#SP2275000

运输信息

UN编号UN3077
类别9
包装类别 III
监管条件代码(*)
T1300000Thioridazine HydrochlorideEuropean Pharmacopoeia (EP) Reference Standard1277.32元/ ;   展开

产品说明

一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

包装

Unit quantity: 100 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

注意

Please find SDS provided by EDQM here..

其他说明

Sales restrictions may apply.

基本信息

经验(实验)分子式C21H26N2S2 · HCl
分子量407.04
MDL编号MFCD00012655
PubChem化学物质编号329826662
NACRESNA.24

产品性质

等级pharmaceutical primary standard
manufacturer/tradenameEDQM
application(s)pharmaceutical (small molecule)
格式neat
储存温度2-8℃
SMILES stringCl.CSc1ccc2Sc3ccccc3N(CCC4CCCCN4C)c2c1
InChI1S/C21H26N2S2.ClH/c1-22-13-6-5-7-16(22)12-14-23-18-8-3-4-9-20(18)25-21-11-10-17(24-2)15-19(21)23;/h3-4,8-11,15-16H,5-7,12-14H2,1-2H3;1H
InChI keyNZFNXWQNBYZDAQ-UHFFFAOYSA-N
Gene Informationhuman ... DRD2(1813), DRD3(1814), DRD4(1815), HTR2A(3356), HTR2C(3358)

安全信息

象形图GHS07
警示用语:Warning
危险声明H302
预防措施声明P264 - P270 - P301 + P312 - P501
危险分类Acute Tox. 4 Oral
储存分类代码11 - Combustible Solids
WGKWGK 3
T9025Sigma-AldrichThioridazine Hydrochloride≥99%1313.15元/5 G;   4221.4元/25 G;   展开

产品说明

应用

盐酸噻哒嗪已被用作嵌入剂,使用方波伏安法(SWV)技术分析双链DNA(dsDNA)的完整性。盐酸噻哒嗪还被用作抑制人肝微粒体中肝酶细胞色素P4502D6(CYP2D6)的阳性对照。

生化/生理作用

D2 多巴胺受体拮抗剂; 吩噻嗪类抗精神病药,减少锥体束外副作用; Ca2+ 通道阻滞剂。

制备说明

250 mg盐酸硫代哒嗪可溶于5 ml水中,生成透明、无色至微黄色溶液。盐酸噻哒嗪也可溶于甲醇、乙醇和氯仿,但不溶于乙醚。

基本信息

经验(实验)分子式C21H26N2S2 · HCl
分子量407.04
EC 号204-992-8
MDL编号MFCD00012655
PubChem化学物质编号57654711
NACRESNA.77

产品性质

质量水平100
测定≥99%
溶解性H2O: soluble 250 mg plus 5 ml of solvent, clear, colorless to faintly yellow
chloroform: soluble
diethyl ether: insoluble
ethanol: soluble
methanol: soluble
SMILES stringCl.CSc1ccc2Sc3ccccc3N(CCC4CCCCN4C)c2c1
InChI1S/C21H26N2S2.ClH/c1-22-13-6-5-7-16(22)12-14-23-18-8-3-4-9-20(18)25-21-11-10-17(24-2)15-19(21)23;/h3-4,8-11,15-16H,5-7,12-14H2,1-2H3;1H
InChI keyNZFNXWQNBYZDAQ-UHFFFAOYSA-N
Gene Informationhuman ... DRD2(1813), DRD3(1814), DRD4(1815), HTR2A(3356), HTR2C(3358)

安全信息

象形图GHS07
警示用语:Warning
危险声明H302
预防措施声明P264 - P270 - P301 + P312 - P501
危险分类Acute Tox. 4 Oral
储存分类代码11 - Combustible Solids
WGKWGK 3
个人防护装备dust mask type N95 (US), Eyeshields, Gloves
PHR3143SupelcoThioridazine Hydrochloridepharmaceutical secondary standard, certified reference material2107.71元/500 mg;   展开

产品说明

一般描述

Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards

分析说明

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

其他说明

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

附注

To see an example of a Certificate of Analysis for this material enter LRAA6959(changes by product) in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

基本信息

经验(实验)分子式C21H26N2S2 · HCl
分子量407.04
MDL编号MFCD00012655

产品性质

等级certified reference material
pharmaceutical secondary standard
CofAcurrent certificate can be downloaded
包装pkg of 500 mg
application(s)pharmaceutical
药典可追溯性traceable to USP 1663008
储存温度2-30℃
SMILES stringCl.CSc1ccc2Sc3ccccc3N(CCC4CCCCN4C)c2c1
InChI1S/C21H26N2S2.ClH/c1-22-13-6-5-7-16(22)12-14-23-18-8-3-4-9-20(18)25-21-11-10-17(24-2)15-19(21)23;/h3-4,8-11,15-16H,5-7,12-14H2,1-2H3;1H
InChI keyNZFNXWQNBYZDAQ-UHFFFAOYSA-N

安全信息

象形图GHS07
警示用语:Warning
危险声明H302
预防措施声明P264 - P270 - P301 + P312 - P501
危险分类Acute Tox. 4 Oral
储存分类代码11 - Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
1663008USPThioridazine HydrochlorideUnited States Pharmacopeia (USP) Reference Standard3231.47元/200 MG;   展开

产品说明

一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

分析说明

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

其他说明

USP issued SDS can be found here.
Sales restrictions may apply.

基本信息

经验(实验)分子式C21H26N2S2 · HCl
分子量407.04
MDL编号MFCD00012655
PubChem化学物质编号329751310
NACRESNA.24

产品性质

等级pharmaceutical primary standard
manufacturer/tradenameUSP
application(s)pharmaceutical (small molecule)
格式neat
SMILES stringCl.CSc1ccc2Sc3ccccc3N(CCC4CCCCN4C)c2c1
InChI1S/C21H26N2S2.ClH/c1-22-13-6-5-7-16(22)12-14-23-18-8-3-4-9-20(18)25-21-11-10-17(24-2)15-19(21)23;/h3-4,8-11,15-16H,5-7,12-14H2,1-2H3;1H
InChI keyNZFNXWQNBYZDAQ-UHFFFAOYSA-N
Gene Informationhuman ... DRD2(1813), DRD3(1814), DRD4(1815), HTR2A(3356), HTR2C(3358)

安全信息

象形图GHS07
警示用语:Warning
危险声明H302
预防措施声明P264 - P270 - P301 + P312 - P501
危险分类Acute Tox. 4 Oral
储存分类代码11 - Combustible Solids
WGKWGK 3
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