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关键词:       仅模糊查询
CAS: 130-26-7
分子式: C9H5ClINO
分子量: 305.52
熔点: 170-172℃
中文名称: 
5-氯-7-碘-8-羟基喹啉
5-氯-8-羟基-7-碘喹啉
氯碘羟喹
氯碘喹啉
5-氯-8-羟基-7-碘代喹啉
英文名称: 
alchoquin
clloquinol
Quinocreme
Vioformo
5-chlor-7-jod-8-hydroxy-chinolin
5-chloro-7-iodo-8-hydroxyquinoline
5-chloro-7-iodo-8-quinolinol
5-chloro-8-hydroxy-7-iodoquinoline
7-iodo-5-chloro-8-hydroxyquinoline
7-iodo-5-chloroxine
5-chloro-7-iodo-8-quinolino
ala-quin
alchloquin
alioform
amebil
amoenol
bactol
barquinol
budoform
chinoform
chloroiodoquin
chloroiodoquine
clioquinol
cliquinol
corque
cortin
cremo-quin
domeform
eczecidin
emaform
enteritan
entero-bio form
entero-septol
entero-vioform
entero-vioformio
enteroquinol
enteroseptol
enterovalodon
enterozol
enterum locorten
entrokin
hi-enterol
hydriodide-enterol
hysone
iodenterol
iodochlorhydroxyquin
iodochlorhydroxyquin cream
iodochlorhydroxyquinol
iodochlorhydroxyquinoline
iodochlorohydroxyquin
iodochlorohydroxyquinoline
iodochloroxyquinoline
iodoenterol
nioform
oralcer
quinambicide
quinoform
rometin
uad lotion
vioform
vioform n.n.r.
vioform-hydrocortisone
vioform-hydrocortisone mild
展开更多英文名
性质描述: 棕黄色轻质粉末。熔点172℃(分解)。1份本品能溶于43份沸醇、128份氯仿、17份沸乙酸乙酯、170份冷乙酸、13份沸乙酸,几乎不溶于水、冷醇和醚。微有特殊异臭,无味,遇光易变质。
生产方法: 由8-羟基喹啉经碘化而得。
用途: 作为药物称氯碘喹啉或消虫痢,主要用于肠道阿米巴痢疾和菌痢,以及因服用抗菌素引起的腹泻,神经性下痢等。
推荐供应商
货号品牌产品名称规格包装、参考价格详情
C797003MACKLIN5-氯-8-羟基-7-碘喹啉10mM in DMSO185元/1ml;   展开
储存:-20°C
C806186MACKLIN5-氯-8-羟基-7-碘喹啉98.0%129元/10g;   517元/50g;   展开
储存:2~8°C
C0187TCI5-Chloro-8-hydroxy-7-iodoquinoline>97.0%(T)340元/25G;   1445元/250G;   展开

基本信息

纯度/分析方法>97.0%(T)
分子式/分子量C9H5ClINO = 305.50
外观与形状(20℃)固体
Reaxys-RN153637
PubChem物质ID87565356
SDBS (AIST Spectral DB)1606
Merck Index (14)5031
MDL编号MFCD00006787

技术规格

AppearanceLight yellow to Brown to Dark green powder to crystal
Purity(HPLC)min. 95.0 area%
Purity(Nonaqueous Titration)min. 97.0 %

安全信息

图形或危害标志
信号词警告
危险性说明H302 : 吞咽有害。
H315 : 造成皮肤刺激。
H319 : 造成严重眼刺激。
H361 : 怀疑对生育能力或胎儿造成伤害。
H317 : 可能造成皮肤过敏反应。
防范说明P501 : 将内装物/容器送到批准的废物处理厂处理。
P261 : 避免吸入粉尘/烟/气体/烟雾/蒸气/喷雾。
P272 : 受沾染的工作服不得带出工作场地。
P270 : 使用本产品时不要进食、饮水或吸烟。
P202 : 在阅读并明了所有安全措施前切勿搬动。
P201 : 使用前取得专用说明。
P264 : 作业后彻底清洗皮肤。
P280 : 戴防护手套/穿防护服/戴防护眼罩/戴防护面具。
P302 + P352 : 如皮肤沾染:用水充分清洗。
P308 + P313 : 如接触到或有疑虑:求医/就诊。
P337 + P313 : 如仍觉眼刺激:求医/就诊。
P305 + P351 + P338 : 如进入眼睛:用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出,取出隐形眼镜。继续冲洗。
P362+P364 : 脱掉沾污的衣服,清洗后方可重新使用。
P333 + P313 : 如发生皮肤刺激或皮疹:求医/就诊。
P301 + P312 + P330 : 如误吞咽:如感觉不适,呼叫急救中心/医生。漱口。
P405 : 存放处须加锁。

相关法规

RTECS#VC5075000
233165Sigma-AldrichClioquinol-CAS 130-26-7-CalbiochemA metal ion chelator that crosses the blood brain barrier and acts as a neurotoxic antibiotic.1203.36元/1 G;   展开

产品说明

一般描述

A metal ion chelator that crosses the blood brain barrier and acts as a neurotoxic antibiotic. Reported to dissolve senile plaques and reduce amyloid’s ability to clump together, apparently by trapping the Cu2+ and Zn2+ that stud these deposits. Shown to increase distal dominant axonopathy in animal models.
A metal ion chelator that crosses the blood-brain barrier and acts as a neurotoxic antibiotic. Reported to dissolve senile plaques and reduce amyloid′s ability to clump together, apparently by trapping the Cu2+ and Zn2+ that reduces the build-up of these deposits. Exhibits greater affinity for Cu2+ and Zn2+ than for Ca2+ and Mg2+. Shown to induce distal dominant axonopathy in animal models. Clioquinol treatment has been shown to be beneficial in a mouse model of Alzheimer′s disease.

包装

1 g in Plastic Bag(s)
Packaged under inert gas

生化/生理作用

Product does not compete with ATP.
Reversible: no
Cell permeable: no
Primary Target
Metal ion chelator

警告

Toxicity: Toxic & Carcinogenic / Teratogenic (G)

重悬

Following reconstitution, aliquot and freeze at -20°C. Stock solutions are stable for up to 3 months at -20°C.

其他说明

Melov, S. 2002. Trends Neurosci.25, 121.
Regland, B., et al. 2001. Dement. Geriatr. Cogn. Disord.12, 408.
Helmuth, L., et al. 2000. Science290, 1273.
Tateishi, J., et al. 2000. Neuropathology20, Suppl: S20-4.
Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.

法律信息

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

基本信息

经验(实验)分子式C9H5ClINO
分子量305.50
MDL编号MFCD00006787

产品性质

质量水平100
测定≥95% (HPLC)
形式solid
manufacturer/tradenameCalbiochem®
储存条件OK to freeze
protect from light
溶解性ethanol: 1 mg/mL
methanol: 1.5 mg/mL
DMSO: 20 mg/mL
运输ambient
储存温度−20℃
InChI1S/C9H5ClINO/c10-6-4-7(11)9(13)8-5(6)2-1-3-12-8/h1-4,13H
InChI keyQCDFBFJGMNKBDO-UHFFFAOYSA-N

安全信息

象形图GHS06
警示用语:Danger
危险声明H301 - H315 - H317 - H319
预防措施声明P261 - P264 - P280 - P301 + P310 - P302 + P352 - P305 + P351 + P338
危险分类Acute Tox. 3 Oral - Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1
储存分类代码6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGKWGK 3
24880Sigma-Aldrich5-Chloro-7-iodo-8-quinolinol≥95.0% (HPLC)956.31元/100 G;   3895.37元/500 G;   展开

产品说明

一般描述

5-Chloro-7-iodo-8-quinolinol is an antibiotic with metal-binding properties and exhibits anticancer activity in vitro and in vivo. 5-Chloro-7-iodo-8-quinolinol, its glucuronide and sulfate in serum, urine and milk has been quantitated by gas chromatography.

应用

5-Chloro-7-iodo-8-quinolinol has been used in analysis of intracellular free zinc ions with the FluoZin-3 probes using fluorescence microscopy.

包装

100, 500 g in poly bottle

基本信息

经验(实验)分子式C9H5ClINO
分子量305.50
Beilstein153637
EC 号204-984-4
MDL编号MFCD00006787
PubChem化学物质编号57648095
NACRESNA.22

产品性质

质量水平200
测定≥95.0% (HPLC)
形式powder
溶解性dioxane: soluble 0.5 g/10 mL, clear, faintly yellow to yellow
SMILES stringOc1c(I)cc(Cl)c2cccnc12
InChI1S/C9H5ClINO/c10-6-4-7(11)9(13)8-5(6)2-1-3-12-8/h1-4,13H
InChI keyQCDFBFJGMNKBDO-UHFFFAOYSA-N

安全信息

象形图GHS06
警示用语:Danger
危险声明H301 - H315 - H317 - H319
预防措施声明P261 - P264 - P280 - P301 + P310 - P302 + P352 - P305 + P351 + P338
危险分类Acute Tox. 3 Oral - Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1
储存分类代码6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGKWGK 3
个人防护装备Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
33931SupelcoClioquinolVETRANAL®, analytical standard636.33元/100 MG;   展开

产品说明

一般描述

Clioquinol is a 8-hydroxyquinoline derivative, which comes under the category of allergens and finds potential applications as an anti-infective agent for diarrhoea. It can be used like a chelator in the treatment of alzheimer′s disease, since it has good affinity towards zinc and copper ions and can easily cross the blood-brain barrier.

应用

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

法律信息

VETRANAL is a registered trademark of sigma-aldrich Chemie GmbH

基本信息

经验(实验)分子式C9H5ClINO
分子量305.50
Beilstein153637
EC 号204-984-4
MDL编号MFCD00006787
PubChem化学物质编号329754701
NACRESNA.24

产品性质

等级analytical standard
质量水平100
产品线VETRANAL®
保质期limited shelf life, expiry date on the label
technique(s)HPLC: suitable
gas chromatography (GC): suitable
application(s)forensics and toxicology
pharmaceutical (small molecule)
格式neat
储存温度2-8℃
SMILES stringOc1c(I)cc(Cl)c2cccnc12
InChI1S/C9H5ClINO/c10-6-4-7(11)9(13)8-5(6)2-1-3-12-8/h1-4,13H
InChI keyQCDFBFJGMNKBDO-UHFFFAOYSA-N

安全信息

象形图GHS06
警示用语:Danger
危险声明H301 - H315 - H317 - H319
预防措施声明P261 - P264 - P280 - P301 + P310 - P302 + P352 - P305 + P351 + P338
危险分类Acute Tox. 3 Oral - Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1
储存分类代码6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGKWGK 3
个人防护装备Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
1138201USPClioquinolUnited States Pharmacopeia (USP) Reference Standard3231.47元/500 MG;   展开

产品说明

一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

分析说明

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

其他说明

USP issued SDS can be found here.
Sales restrictions may apply.

基本信息

经验(实验)分子式C9H5ClINO
分子量305.50
Beilstein153637
MDL编号MFCD00006787
PubChem化学物质编号329749425
NACRESNA.24

产品性质

等级pharmaceutical primary standard
manufacturer/tradenameUSP
application(s)pharmaceutical (small molecule)
格式neat
储存温度2-8℃
SMILES stringOc1c(I)cc(Cl)c2cccnc12
InChI1S/C9H5ClINO/c10-6-4-7(11)9(13)8-5(6)2-1-3-12-8/h1-4,13H
InChI keyQCDFBFJGMNKBDO-UHFFFAOYSA-N

安全信息

象形图GHS06
警示用语:Danger
危险声明H301 - H315 - H317 - H319
预防措施声明P261 - P264 - P280 - P301 + P310 - P302 + P352 - P305 + P351 + P338
危险分类Acute Tox. 3 Oral - Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1
储存分类代码6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
BP084ClioquinolBritish Pharmacopoeia (BP) Reference Standard1861.35元/200 MG;   展开

产品说明

一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

包装

Unit quantity: 200 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity please visit British Pharmacopoeia

其他说明

Sales restrictions may apply.

基本信息

经验(实验)分子式C9H5ClINO
分子量305.50
Beilstein153637
EC 号204-984-4
MDL编号MFCD00006787
NACRESNA.24

产品性质

等级pharmaceutical primary standard
manufacturer/tradenameBP
格式neat
储存温度2-8℃
SMILES stringOc1c(I)cc(Cl)c2cccnc12
InChI1S/C9H5ClINO/c10-6-4-7(11)9(13)8-5(6)2-1-3-12-8/h1-4,13H
InChI keyQCDFBFJGMNKBDO-UHFFFAOYSA-N

安全信息

象形图GHS06
警示用语:Danger
危险声明H301 - H315 - H317 - H319
预防措施声明P261 - P264 - P280 - P301 + P310 - P302 + P352 - P305 + P351 + P338
危险分类Acute Tox. 3 Oral - Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1
储存分类代码6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGKWGK 3
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