CAS 125-85-9; cyclopentanecarboxylic acid, 1-phenyl-, 2-(diethylamino)ethyl ester, hydrochlor

CAS:

125-85-9

分子式:

C18H28ClNO2

分子量:

325.87

英文名称:

cyclopentanecarboxylic acid, 1-phenyl-, 2-(diethylamino)ethyl ester, hydrochlor

1-phenylcyclopentanecarboxylic acid 2-diethylaminoethyl ester hydrochloride

caramiphen

caramiphen hydrochloride

caramiphene hydrochloride

caramiphenium chloride

diethylaminoethyl-1-phenylcyclopentane-1-carboxylate hydrochloride

geigy 2747

hydrochloride of 1-phenylcyclopentanecarboxylic acid diethylaminoethyl ester

parpanit

pentaphene hydrochloride

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用途:

Caramiphen hydrochloride has been used to test its inhibitory effect on voltage-gated Na+ currents using the patch-clamp method.

推荐供应商

货号

品牌

产品名称

规格

包装、参考价格

详情

C920563

MACKLIN

盐酸咳美芬

≥98% (HPLC)

2213元/10mg;

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储存：2-8°C
状态：粉末

SML0319

Sigma-Aldrich

Caramiphen hydrochloride

≥98% (HPLC)

2532.84元/10 MG; 10142.9元/50 MG;

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产品说明

应用

Caramiphen hydrochloride has been used to test its inhibitory effect on voltage-gated Na⁺currents using the patch-clamp method.

包装

10, 50 mg in glass bottle

生化/生理作用

Caramiphen hydrochloride is non-narcotic and possesses many biological functionalities of being antitussive, anticonvulsive, and neuroprotective. It induces sensory block and displays less toxicity when compared to bupivacaine. The local anesthetic functionality of caramiphen is mediated by its inhibitory effect on voltage-gated Na⁺ currents.
Caramiphen is an anti-muscarinic similar to atropine; muscarinic acetylcholine receptor antagonist. Caramiphen is commonly used as a cough suppresant, but is also administered for the treatment of Parkinson′s disease. The compound has also been shown to have anti-depressant properties that may involve inhibition of G protein-coupled inwardly rectifying potassium channel GIRK.

特点和优势

This compound is featured on the Acetylcholine Receptors (Muscarinic) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

基本信息

经验(实验)分子式	C₁₈H₂₇NO₂ · HCl
分子量	325.87
MDL编号	MFCD00242608
PubChem化学物质编号	329825324
NACRES	NA.77

产品性质

质量水平	100
测定	≥98% (HPLC)
形式	powder
颜色	white to beige
溶解性	H₂O: ≥5 mg/mL
储存温度	2-8℃
SMILES string	Cl.CCN(CC)CCOC(=O)C1(CCCC1)c2ccccc2
InChI	1S/C18H27NO2.ClH/c1-3-19(4-2)14-15-21-17(20)18(12-8-9-13-18)16-10-6-5-7-11-16;/h5-7,10-11H,3-4,8-9,12-15H2,1-2H3;1H
InChI key	MUPNXGNOIBYHSG-UHFFFAOYSA-N

安全信息

象形图
警示用语：	Warning
危险声明	H302
危险分类	Acute Tox. 4 Oral
储存分类代码	13 - Non Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable