CAS 1245603-92-2; pf-04937319

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CAS:

1245603-92-2

分子式:

C₂₂H₂₀N₆O₄

分子量:

432.43

英文名称:

pf-04937319

n,n-dimethyl-5-[[2-methyl-6-[[(5-methyl-2-pyrazinyl)amino]carbonyl]-4-benzofuranyl]oxy]-2-pyrimidinecarboxamide

n, n-dimethyl-5-((2-methyl-6-((5-methylpyrazin-2-yl)carbamoyl)benzofuran-4-yl)oxy)pyrimidine-2-carboxamide

推荐供应商

货号

品牌

产品名称

规格

包装、参考价格

详情

P993549

MACKLIN

PF 04937319,葡糖激酶部分激活剂

99.7%

943元/5mg; 3341元/25mg;

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储存：2-8°C, 密封, 干燥
状态：粉末

PZ0320

Sigma-Aldrich

PF-04937319

≥98% (HPLC)

1117.23元/5 MG; 4498.97元/25 MG;

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产品说明

一般描述

PF-04937319 is a partial activator of glycokinase (GK) enzyme.

包装

5, 25 mg in glass bottle

生化/生理作用

PF-04937319 is a glucokinase activator with an EC₅₀ value of 174 nM. PF-04937319 was found to improve glycemic control in adults with type 2 diabetes when used in conjunction with metformin.
PF-04937319, unlike other glucokinase activators, is capable of maintaining lower-glucose levels without it resulting in hypoglycemia. In type II diabetic patients where metformin treatment is inadequate, PF-04937319 is capable of maintaining glycemic control within the acceptable risk-benefit profile.

其他说明

This compound was developed by Pfizer for Cytokines & Growth Factors research. To learn more about Sigma′s partnership with Pfizer and view other authentic, high-quality Pfizer compounds, visit sigma.com/bsm-pfizer.

法律信息

Sold for research purposes under agreement from Pfizer Inc.
Pfizer is a registered trademark of Pfizer, Inc.

基本信息

经验(实验)分子式	C₂₂H₂₀N₆O₄
分子量	432.43
MDL编号	MFCD26960571
PubChem化学物质编号	329823838
NACRES	NA.77

产品性质

质量水平	100
测定	≥98% (HPLC)
形式	powder
manufacturer/tradename	Pfizer^®
颜色	white to beige
溶解性	DMSO: 20 mg/mL, clear
创始人	Pfizer
储存温度	room temp
SMILES string	CC(O1)=CC2=C1C=C(C(NC3=NC=C(C)N=C3)=O)C=C2OC4=CN=C(C(N(C)C)=O)N=C4
InChI	1S/C22H20N6O4/c1-12-8-24-19(11-23-12)27-21(29)14-6-17-16(5-13(2)31-17)18(7-14)32-15-9-25-20(26-10-15)22(30)28(3)4/h5-11H,1-4H3,(H,24,27,29)
InChI key	MASKQITXHVYVFL-UHFFFAOYSA-N

安全信息

储存分类代码	13 - Non Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable

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