CAS 1228280-29-2; ky-05009

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CAS:

1228280-29-2

分子式:

C₁₈H₁₆N₄O₂S

分子量:

352.41

英文名称:

ky-05009

5-(4-methylbenzamido)-2-(phenylamino)thiazole-4-carboxamide

5-[(4-methylbenzoyl)amino]-2-(phenylamino)-4-thiazolecarboxamide

推荐供应商

货号

品牌

产品名称

规格

包装、参考价格

K920766

MACKLIN

KY-05009

≥98%(HPLC)

119元/5mg; 471元/25mg; 1410元/100mg; 2382元/250mg;

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储存：2-8°C，干燥，密封

SML1506

Sigma-Aldrich

KY-05009

≥98% (HPLC)

1260.64元/5 MG; 5077.25元/25 MG;

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产品说明

包装

5, 25 mg in glass bottle

生化/生理作用

KY-05009 is a Traf2- and Nck-interacting kinase (TNIK) inhibitor that inhibits the epithelial-to-mesenchymal transition (EMT) in cancer cells.
KY-05009 is also known as (5-(4-methylbenzamido)-2-(phenylamino) thiazole-4-carboxamide). It prevents the proliferation induced by interleukin-6 and promotes cell death by blocking Wnt signaling in multiple myeloma (MM) cells. KY-05009 is a novel aminothiazole, which possesses anti-cancer activity in human colorectal cancer cells. KY-05009 prevents migration and invasion stimulated by TGF-β1 (transforming growth factor beta 1).

基本信息

经验(实验)分子式	C₁₈H₁₆N₄O₂S
分子量	352.41
PubChem化学物质编号	329825926
NACRES	NA.77

产品性质

质量水平	100
测定	≥98% (HPLC)
形式	powder
颜色	light yellow to dark yellow
溶解性	DMSO: 10 mg/mL, clear
储存温度	2-8℃
SMILES string	NC(C1=C(NC(C2=CC=C(C)C=C2)=O)SC(NC3=CC=CC=C3)=N1)=O
InChI	1S/C18H16N4O2S/c1-11-7-9-12(10-8-11)16(24)22-17-14(15(19)23)21-18(25-17)20-13-5-3-2-4-6-13/h2-10H,1H3,(H2,19,23)(H,20,21)(H,22,24)
InChI key	WCEDGRTWDSHZHF-UHFFFAOYSA-N

安全信息

储存分类代码	13 - Non Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable

538209

Fluorochem

5-(4-Methylbenzamido)-2-(phenylamino)thiazole-4-carboxamide

95%

5786元/250mg; 14432元/1g; 43318元/5g;

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基本信息

CAS Number	1228280-29-2
MDL Number	MFCD29059915

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