基本信息

技术规格

物性(参考值)

安全信息

图形或危害标志
信号词	警告
危险性说明	H315 : 造成皮肤刺激。 H319 : 造成严重眼刺激。
防范说明	P264 : 作业后彻底清洗皮肤。 P280 : 戴防护手套/戴防护眼罩/戴防护面具。 P302 + P352 : 如皮肤沾染：用水充分清洗。 P337 + P313 : 如仍觉眼刺激：求医/就诊。 P305 + P351 + P338 : 如进入眼睛：用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出，取出隐形眼镜。继续冲洗。 P362+P364 : 脱掉沾污的衣服，清洗后方可重新使用。 P332 + P313 : 如发生皮肤刺激：求医/就诊。

基本信息

安全信息

图形或危害标志
提示语	Warning
危险说明	H315 H319 H335
防范说明	P261 P305+P351+P338
WGK	3
TSCA	否

Technical Notes:

1.Precursor to catalysts for the asymmetric hydrogenation of tri- and tetrasubstituted olefins.

2.Precursor to catalyst for enantioselective reduction of imines.

3.Precursor to catalyst for allylic alkylation.

4.Precursor to catalyst for allylic amination and etherification.

5.Precursor to catalyst for the reaction of aroyl chlorides with internal alkynes to produce substituted naphthalenes and anthracenes.

6.Ir-catalyzed addition of acid chlorides to terminal alkynes.

7.Intramolecular hyd roamination of unactivated alkenes with secondary alkyI- and arylamines.

8.Enantioselective 2+ 2 cycloaddition.

9.Silyl-directed, Ir-catalyzed ortho-b orylation of arenes.

10.Ir-catalyzed cros s-coupling of styrene derivatives with allylic carbonates .

11.Transfer hydrogenative C-C coupling

References:

1.Angew. Chem. Int. Ed., 1998, 37, 2897.

2.J. Am. Chem. Soc., 1999, 121, 6421.

3.J. Am. Chem. Soc., 1998, 120, 8647.

4.J. Am. Chem. Soc, 2003, 125, 14272.

5.J. Am. Chem. Soc., 2002, 124, 12680.

6.J. Am. Chem. Soc, 2009, 131, 6668.

7.J. Am. Chem. Soc., 2010, 132, 413.

8.Org. L ett., 2010, 12, 304.

9.J. Am. Chem. Soc, 2008, 130, 7534.

10.J. Am. Chem. Soc., 2009, 131, 8346.

11.（a）J. Am. Chem. Soc., 2008, 130, 6340. (b) Angew. Chem. Int. Ed., 2009, 48, 6313.

应用
Chloro(1,5-cyclooctadiene)iridium(I) dimer is widely used as a precursor to other iridium complexes, which finds application in homogeneous catalysis like carbonylation, hydrosilylation, hydrofomylation, asymmetric allylic substitutions, metathesis and chiral catalysis reactions. It is involved in the preparation of Crabtree's catalyst, which is used for hydrogenation and hydrogen-transfer reactions.

备注
Moisture sensitive. Incompatible with strong oxidizing agents.

基本信息

MDL
MFCD00012414

EINECS
235-170-7

分子式
C₁₆H₂₄Cl₂Ir₂

分子量
671.71

熔点
190° dec.

灵敏度
Ambient temperatures.

形态
Crystalline powder

溶解性
Soluble in chloroform and toluene. Slightly soluble in acetone and alcohol. Insoluble in water.

GHS危害和防范说明

GHS符号

Hazard Statements
H315-H319-H335
Causes skin irritation.Causes serious eye irritation.May cause respiratory irritation.

Precautionary Statements
P261-P280a-P305+P351+P338-P304+P340-P405-P501a
Avoid breathing dust/fume/gas/mist/vapours/spray.Wear protective gloves and eye/face protection.IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing.Store locked up.Dispose of contents/container in accordance with local/regional/national/international regulations.

安全信息

危险类别
36/37/38
Irritating to eyes, respiratory system and skin.

安全等级
26-37-60
In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.This material and its container must be disposed of as hazardous waste

TSCA
否

基本信息

Ref#
36396

MDL
12414

分子式
C16 H24 Cl2 Ir2

分子量
671.68

产品说明

应用

用于不对称和交叉偶联催化的 Umicore 预催化剂

不对称烯丙基取代的金属前体。

包装

2 g in glass bottle
500 mg in glass bottle

法律信息

Umicore 产品

更多信息请参见 www.pmc.umicore.com

基本信息

产品性质

安全信息

基本信息

安全信息

图形或危害标志
危险性说明	H315: Causes skin irritation. H319: Causes serious eye irritation. H335: May cause respiratory irritation.
防范说明	P233: Keep container tightly closed. P260: Do not breathe . P261: Avoid breathing . P264: Wash hands thoroughly after handling. P271: Use only outdoors or in a well-ventilated area. P280: Wear . P302 + P352: IF ON SKIN: Wash with plenty of soap and water. P304: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.. P304 + P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing. P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P312: Call a POISON CENTER or doctor/physician if you feel unwell. P321: Specific treatment (see relevant procedures. on this label). P332 + P313: If skin irritation occurs: Get medical advice/ attention. P337 + P313: If eye irritation persists: Get medical advice/attention. P340: Remove victim to fresh air and keep at rest in a position comfortable for breathing. P362: Take off contaminated clothing and wash before reuse. P403: Store in a well-ventilated place. P403 + P233: Store in a well-ventilated place. Keep container tightly closed. P405: Store locked up. P501: Dispose of contents/container to in accordance with local regulation .