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CAS: 121-71-1
分子式: C8H8O2
分子量: 136.15
沸点: 296℃
熔点: 94-97℃
中文名称: 
3'-羟基苯乙酮
间羟基苯乙酮
间羟基乙酰苯
间乙酰苯酚
3-羟基苯乙酮
3-羟基乙酸苯酮
英文名称: 
1-(3-hydroxyphenyl)-ethanon
3'-hydroxyacetophenone
1-(3-hydroxy-phenyl)-ethanone
Ethanone,1-(3-hydroxyphenyl)-
1-(3-Hydroxyphenyl)ethanone
m-Acetylphenol
3-Hydroxyphenyl methyl ketone
3-hydroxy acetophenone
3-Acetophenol
3-Acetylphenol
性质描述: 针状体结晶。熔点95-97℃,沸点296℃,153℃(0.67kPa),相对密度1.099(109℃),折光率1.5348。溶于乙醇、乙醚、氯仿和苯,微溶于水,不溶于石油英。
生产方法: 由间氨基苯乙酮与亚硝酸钠反应而得。将水和浓硫酸加入反应锅内,搅拌下加入间氨基苯乙酮,然后在冷却下滴加亚硝酸钠水溶液,温度保持在8-10℃,加毕慢慢升温至90℃以上,继续搅拌反应1h。冷却析出固体,甩滤,得到的粗品用热水重结晶,即得间羟基苯乙酮。收率65%。
用途: 用于有机合成,是药物苯肾上腺素的中间体。
推荐供应商
货号品牌产品名称规格包装、参考价格详情
H810990MACKLIN3-羟基苯乙酮98%30元/25g;   96元/100g;   405元/500g;   1998元/2.5kg;   展开
储存:室温
状态:白色到黄色到棕褐色到黄色-棕色到棕色粉末或晶体
折射率:1,534
A0104TCI3'-Hydroxyacetophenone>98.0%(GC)(T)190元/25G;   750元/100G;   2745元/500G;   展开

基本信息

纯度/分析方法>98.0%(GC)(T)
分子式/分子量C8H8O2 = 136.15
外观与形状(20℃)固体
Reaxys-RN2040676
PubChem物质ID87561799
SDBS (AIST Spectral DB)1016
MDL编号MFCD00002298

技术规格

AppearanceWhite to Light yellow to Light orange powder to crystal
Purity(GC)min. 98.0 %
Purity(Neutralization titration)min. 98.0 %
Melting point93.0 to 97.0 ℃
Solubility in Methanolalmost transparency

物性(参考值)

熔点94 ℃
沸点153 ℃/5 mmHg

安全信息

图形或危害标志
信号词警告
危险性说明H315 : 造成皮肤刺激。
H319 : 造成严重眼刺激。
防范说明P264 : 作业后彻底清洗皮肤。
P280 : 戴防护手套/戴防护眼罩/戴防护面具。
P302 + P352 : 如皮肤沾染:用水充分清洗。
P337 + P313 : 如仍觉眼刺激:求医/就诊。
P305 + P351 + P338 : 如进入眼睛:用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出,取出隐形眼镜。继续冲洗。
P362+P364 : 脱掉沾污的衣服,清洗后方可重新使用。
P332 + P313 : 如发生皮肤刺激:求医/就诊。
500471J&K3'-Hydroxyacetophenone99%123元/25G;   306元/100G;   展开

基本信息

分子式C8H8O2
分子量136.15
熔点90-95
沸点296
密度1.1
MDL编码MFCD00002298
Beilstein2040676
EINECS 编号204-494-0

安全信息

图形或危害标志
提示语Warning
危险说明H302
防范说明P260
P262
WGK3
TSCA
A12547Alfa Aesar3'-Hydroxyacetophenone98%1676元/100g;   6303元/500g;   展开

应用
3?’Hydroxyacetophenone is used in the preparation of chalcones and flavonoids, which finds application as an anti-tuberculosis agent and antileishmanial chaocones. It is also involved in the preparation of phenylephrine. Further, it is an active component of castoreum, which is used as a tincture in some perfumes and as a food additive.

备注
Incompatible with strong oxidizing agents and bases.

基本信息

MDL
MFCD00002298

EINECS
204-494-0

分子式
C8H8O2

分子量
136.15

熔点
93-97°

沸点
296°

密度
1.1

灵敏度
Ambient temperatures.

形态
Crystalline powder

溶解性
Soluble in alcohol. Insoluble in water.

Beilstein
2040676

GHS危害和防范说明

GHS符号

Hazard Statements
H315-H319-H335
Causes skin irritation.Causes serious eye irritation.May cause respiratory irritation.

Precautionary Statements
P261-P280a-P305+P351+P338-P304+P340-P405-P501a
Avoid breathing dust/fume/gas/mist/vapours/spray.Wear protective gloves and eye/face protection.IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing.Store locked up.Dispose of contents/container in accordance with local/regional/national/international regulations.

安全信息

危险类别
36/37/38
Irritating to eyes, respiratory system and skin.

安全等级
26-37-60
In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.This material and its container must be disposed of as hazardous waste

TSCA

C41191Alfa Aesar3'-Hydroxyacetophenone99+%526元/5g;   7744元/100g;   展开

基本信息

Ref#
41191

MDL
2298

分子式
C8 H8 O2

分子量
136.15

形态
White to pale brown cryst powder

H18801Sigma-Aldrich3′-Hydroxyacetophenone97%357.98元/25 G;   802.37元/100 G;   展开

基本信息

线性分子式HOC6H4COCH3
分子量136.15
Beilstein2040676
EC 号204-494-0
MDL编号MFCD00002298
PubChem化学物质编号24895488
NACRESNA.22

产品性质

质量水平100
测定97%
bp296 ℃ (lit.)
mp90-95 ℃ (lit.)
密度1.1 g/mL at 25 ℃ (lit.)
SMILES stringCC(=O)c1cccc(O)c1
InChI1S/C8H8O2/c1-6(9)7-3-2-4-8(10)5-7/h2-5,10H,1H3
InChI keyLUJMEECXHPYQOF-UHFFFAOYSA-N

安全信息

储存分类代码13 - Non Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
个人防护装备dust mask type N95 (US), Eyeshields, Gloves
078748Fluorochem3'-Hydroxyacetophenone98%220元/1g;   308元/25g;   660元/100g;   1430元/250g;   2640元/500g;   展开

基本信息

CAS Number121-71-1
MDL NumberMFCD00002298
Boiling Point296 ℃ at 760 mmHg
Melting Point90-95℃
Density1.1

安全信息

图形或危害标志
危险性说明 H302: Harmful if swallowed.
H315: Causes skin irritation.
H319: Causes serious eye irritation.
H335: May cause respiratory irritation.
防范说明 P233: Keep container tightly closed.
P260: Do not breathe .
P261: Avoid breathing
P264: Wash hands thoroughly after handling.
P270: Do not eat, drink or smoke when using this product.
P271: Use only outdoors or in a well-ventilated area.
P280: Wear .
P301 + P312: IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell.
P302 + P352: IF ON SKIN: Wash with plenty of soap and water.
P304: IF INHALED: .
P304 + P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P312: Call a POISON CENTER or doctor/physician if you feel unwell.
P321: Specific treatment (see . on this label).
P330: Rinse mouth.
P332 + P313: If skin irritation occurs: Get medical advice/ attention.
P337 + P313: If eye irritation persists: Get medical advice/attention.
P340: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P362: Take off contaminated clothing and wash before reuse.
P403: Store in a well-ventilated place.
P403 + P233: Store in a well-ventilated place. Keep container tightly closed.
P405: Store locked up.
P501: Dispose of contents/container to local regulations.
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