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CAS: 119-67-5
分子式: C8H6O3
分子量: 150.13
熔点: 96-99℃
中文名称: 
2-碳酰苯甲醛
邻羧基苯甲醛
2-甲酰苯甲酸
2-羧基苯甲醛
英文名称: 
Benzaldehyde-2-carboxylic Acid
phthalaldehydic acid
2-carboxybenzaldehyde
2-formylbenzoic acid
2-formyl-benzoic aci
o-carboxybenzaldehyde
o-formylbenzoic acid
o-Phthalalde-hydic acid
Benzaldehyde-o-carboxylic acid
性质描述: 该品为叶状体结晶。熔点98-99℃(96-98℃)。
生产方法: 由苯酚经溴化、水解而得。将苯酞加热到140-145℃,通溴反应,控制通入速度,使反应尾气基本上无溴蒸气排出。通溴毕,在120℃通二氧化碳与减压将残留的溴化氢除出。反应物加水,在沸腾水浴内水解0.5h。冷却,析出邻羧基苯甲醛。收率60%。
用途: 用作医药中间体。
推荐供应商
货号品牌产品名称规格包装、参考价格详情
C830824MACKLIN邻羧基苯甲醛99%27元/5g;   36元/25g;   132元/100g;   608元/500g;   展开
储存:室温,密封
状态:白色粉末或晶体
C708189MACKLIN邻羧基苯甲醛分析对照品, ≥99%198元/1g;   展开
储存:室温,密封
P0281TCIPhthalaldehydic Acid>98.0%(T)(HPLC)160元/25G;   490元/100G;   2190元/500G;   展开

基本信息

纯度/分析方法>98.0%(T)(HPLC)
分子式/分子量C8H6O3 = 150.13
外观与形状(20℃)固体
Reaxys-RN742381
PubChem物质ID87574517
SDBS (AIST Spectral DB)1691
MDL编号MFCD00003336

技术规格

AppearanceWhite to Almost white powder to crystal
Purity(HPLC)min. 98.0 area%
Purity(Neutralization titration)min. 98.0 %
Melting point97.0 to 100.0 ℃

物性(参考值)

熔点98 ℃

安全信息

图形或危害标志
信号词警告
危险性说明H315 : 造成皮肤刺激。
H319 : 造成严重眼刺激。
防范说明P264 : 作业后彻底清洗皮肤。
P280 : 戴防护手套/戴防护眼罩/戴防护面具。
P302 + P352 : 如皮肤沾染:用水充分清洗。
P337 + P313 : 如仍觉眼刺激:求医/就诊。
P305 + P351 + P338 : 如进入眼睛:用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出,取出隐形眼镜。继续冲洗。
P362+P364 : 脱掉沾污的衣服,清洗后方可重新使用。
P332 + P313 : 如发生皮肤刺激:求医/就诊。

相关法规

RTECS#TH7015000
159270J&K2-Carboxybenzaldehyde99%99元/25G;   275元/100G;   1101元/500G;   展开

基本信息

分子式C8H6O3
分子量150.13
熔点94-96
MDL编码MFCD00003336
Beilstein742381
EINECS 编号204-342-3

安全信息

图形或危害标志
提示语Warning
危险说明H315
H319
H335
防范说明P261
P305+P351+P338
WGK2
RTECSTH7015000
TSCA
A11201Alfa Aesar2-Carboxybenzaldehyde98+%1122元/50g;   4775元/250g;   16450元/1000g;   展开

应用
2-Carboxybenzaldehyde is a carboxylated derivative of benzaldehyde which is readily converted to 2-hydroxymethyl benzoic acid by CBA dehydrogenase. 2-Carboxybenzaldehyde is a metabolite of ampicillin phthalidyl ester. It has been used to synthesize a series of N-substituted isoindolinones by reductive C-N coupling and intramolecular amidation with amines.

备注
Air Sensitive. Store away from air and oxidizing agents. Incompatible with strong bases.

基本信息

MDL
MFCD00003336

EINECS
204-342-3

分子式
C8H6O3

分子量
150.13

熔点
97-101°

闪点
198°(388°F)

密度
1.404

灵敏度
Air Sensitive. Ambient temperatures.

形态
Crystalline powder

溶解性
Soluble in water.

Beilstein
742381

GHS危害和防范说明

GHS符号

Hazard Statements
H315-H319-H335
Causes skin irritation.Causes serious eye irritation.May cause respiratory irritation.

Precautionary Statements
P261-P280a-P305+P351+P338-P304+P340-P405-P501a
Avoid breathing dust/fume/gas/mist/vapours/spray.Wear protective gloves and eye/face protection.IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing.Store locked up.Dispose of contents/container in accordance with local/regional/national/international regulations.

安全信息

危险类别
36/37/38
Irritating to eyes, respiratory system and skin.

安全等级
26-37
In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.

RTECS
TH7015000

TSCA

C15208Alfa Aesar2-Carboxybenzaldehyde99%659元/25g;   1550元/100g;   展开

基本信息

Ref#
15208

MDL
3336

分子式
C8 H6 O3

分子量
150.13

形态
White to cream cryst powder

116017Sigma-Aldrich2-Carboxybenzaldehyde97%426.85元/25 G;   987.83元/100 G;   展开

产品说明

应用

2-羧基苯甲醛是使用两种纯细菌菌株 巴斯德菌 进行的荧蒽生物降解的代谢产物。IFA (B-2) 和 分枝杆菌 吡咯-1 (AM) 。它被用于通过还原 C-N 偶联和与胺的分子内酰胺化来合成一系列 N-取代异吲哚酮 。

包装

25, 100 g in poly bottle

基本信息

经验(实验)分子式C8H6O3
分子量150.13
Beilstein742381
EC 号204-342-3
MDL编号MFCD00003336
PubChem化学物质编号24847258
NACRESNA.22

产品性质

质量水平100
测定97%
mp94-96 ℃ (lit.)
SMILES stringOC(=O)c1ccccc1C=O
InChI1S/C8H6O3/c9-5-6-3-1-2-4-7(6)8(10)11/h1-5H,(H,10,11)
InChI keyDYNFCHNNOHNJFG-UHFFFAOYSA-N

安全信息

象形图GHS07
警示用语:Warning
危险声明H315 - H319 - H335
预防措施声明P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
危险分类Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官Respiratory system
储存分类代码11 - Combustible Solids
WGKWGK 2
闪点(F)Not applicable
闪点(C)Not applicable
个人防护装备dust mask type N95 (US), Eyeshields, Gloves
078754Fluorochem2-Carboxybenzaldehyde97%220元/1g;   352元/25g;   1056元/100g;   展开

基本信息

CAS Number119-67-5
MDL NumberMFCD00003336

安全信息

图形或危害标志
危险性说明 H315: Causes skin irritation.
H319: Causes serious eye irritation.
H335: May cause respiratory irritation.
防范说明 P233: Keep container tightly closed.
P260: Do not breathe .
P261: Avoid breathing .
P264: Wash hands thoroughly after handling.
P271: Use only outdoors or in a well-ventilated area.
P280: Wear .
P302 + P352: IF ON SKIN: Wash with plenty of soap and water.
P304: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing..
P304 + P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P312: Call a POISON CENTER or doctor/physician if you feel unwell.
P321: Specific treatment (see relevant procedures. on this label).
P332 + P313: If skin irritation occurs: Get medical advice/ attention.
P337 + P313: If eye irritation persists: Get medical advice/attention.
P340: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P362: Take off contaminated clothing and wash before reuse.
P403: Store in a well-ventilated place.
P403 + P233: Store in a well-ventilated place. Keep container tightly closed.
P405: Store locked up.
P501: Dispose of contents/container to in accordance with local regulation .
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