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CAS: 119-56-2
分子式: C13H11ClO
分子量: 218.68
熔点: 58-60℃
中文名称: 
对氯二苯甲醇
4-氯二苯甲醇
4-氯双苯甲醇
4-氯苯基苯基甲醇
英文名称: 
4-Chlorodiphenylmethanol
4-Chlorophenyl phenyl carbinol
4-Chlorodiphenylcarbinol
4-chloro- alpha-phenyl-benzenemethano
4-chlorobenzhydrol
性质描述: 熔点58-60℃。
生产方法: 由苯甲酰氯经缩合、还原而得。1.缩合在干燥的反应锅内,加入氯苯和无水三氯化铝,搅拌升温至50℃,滴加苯甲酰氯。加毕,在100-110℃反应5.5h,慢慢放入微酸性冰水中,搅匀后静置,分去上层清液,沉淀甩滤,水洗至中性,甩干。得4-氯双苯酮。收率为95%。2.还原将4-氯双苯酮、液碱加入反应锅,搅拌升温至100℃,慢慢加入锌粉,控制温度在110-125℃。加完后反应8h。静置,分取油层,用热水和少量盐酸洗涤,再用热水洗至pH为6.5,加苯搅拌溶解。静置,分取苯层,蒸苯,余液为成品。
用途: 用于制造抗过敏药西替利嗪。
推荐供应商
货号品牌产品名称规格包装、参考价格详情
C830852MACKLIN4-氯二苯甲醇98%29元/5g;   47元/25g;   148元/100g;   570元/500g;   展开
储存:室温,密封
状态:白色到几乎白色粉末到晶体
C0989TCI4-Chlorobenzhydrol>98.0%(GC)400元/25G;   2450元/500G;   展开

基本信息

纯度/分析方法>98.0%(GC)
分子式/分子量C13H11ClO = 218.68
外观与形状(20℃)固体
Reaxys-RN2050235
PubChem物质ID87566034
SDBS (AIST Spectral DB)23474
MDL编号MFCD00004491

技术规格

AppearanceWhite to Almost white powder to crystal
Purity(GC)min. 98.0 %
Melting point60.0 to 63.0 ℃

物性(参考值)

熔点61 ℃
沸点151 ℃/2.6 mmHg

安全信息

危险性说明H412 : 对水生生物有害并具有长期持续影响。
防范说明P501 : 将内装物/容器送到批准的废物处理厂处理。
P273 : 避免释放到环境中。
166211J&K4-Chlorobenzhydrol98%66元/5G;   238元/25G;   782元/100G;   展开

基本信息

分子式C13H11ClO
分子量218.68
熔点58-60
MDL编码MFCD00004491
Beilstein2050235
EINECS 编号204-333-4

安全信息

WGK3
TSCA
B23691Alfa Aesar4-Chlorobenzhydrol98%794元/5g;   1840元/25g;   5537元/100g;   展开

基本信息

MDL
MFCD00004491

EINECS
204-333-4

分子式
C13H11ClO

分子量
218.68

熔点
58-62°

沸点
150-151°/2.6mm

形态
Powder

Beilstein
2050235

安全信息

TSCA

124982Sigma-Aldrich4-Chlorobenzhydrol98%273.86元/1 G;   展开

产品说明

应用

4-氯苯并氢苯酚可用作为内标,通过气相色谱-质谱法测定尿液中的 N-去甲基安替比林代谢物。它也被用于抗组胺西替利嗪的鉴定,作为卡马西平特异性酶联免疫吸附试验的相关交叉反应剂。

包装

1 g in glass bottle

基本信息

线性分子式ClC6H4CH(C6H5)OH
分子量218.68
EC 号204-333-4
MDL编号MFCD00004491
PubChem化学物质编号24847638
NACRESNA.22

产品性质

质量水平100
测定98%
mp58-60 ℃ (lit.)
SMILES stringOC(c1ccccc1)c2ccc(Cl)cc2
InChI1S/C13H11ClO/c14-12-8-6-11(7-9-12)13(15)10-4-2-1-3-5-10/h1-9,13,15H
InChI keyAJYOOHCNOXWTKJ-UHFFFAOYSA-N

安全信息

储存分类代码13 - Non Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
个人防护装备Eyeshields, Gloves, type N95 (US)
Y0001310Meclozine impurity BEuropean Pharmacopoeia (EP) Reference Standard1259.15元/ ;   展开

产品说明

一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

包装

Unit quantity: 15 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

注意

Please find SDS provided by EDQM here..

其他说明

Sales restrictions may apply.

基本信息

线性分子式ClC6H4CH(C6H5)OH
分子量218.68
MDL编号MFCD00004491
PubChem化学物质编号329831356
NACRESNA.24

产品性质

等级pharmaceutical primary standard
manufacturer/tradenameEDQM
mp58-60 ℃ (lit.)
application(s)pharmaceutical (small molecule)
格式neat
储存温度2-8℃
SMILES stringOC(c1ccccc1)c2ccc(Cl)cc2
InChI1S/C13H11ClO/c14-12-8-6-11(7-9-12)13(15)10-4-2-1-3-5-10/h1-9,13,15H
InChI keyAJYOOHCNOXWTKJ-UHFFFAOYSA-N

安全信息

储存分类代码13 - Non Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
PHR3034SupelcoMeclizine Related Compound Apharmaceutical secondary standard, certified reference material5330.94元/30 mg;   展开

产品说明

一般描述

Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards

分析说明

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

其他说明

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

基本信息

线性分子式ClC6H4CH(C6H5)OH
分子量218.68
MDL编号MFCD00004491

产品性质

等级certified reference material
pharmaceutical secondary standard
CofAcurrent certificate can be downloaded
包装pkg of 30 mg
mp58-60 ℃ (lit.)
application(s)pharmaceutical
药典可追溯性traceable to USP 1377010
储存温度2-8℃
SMILES stringOC(c1ccccc1)c2ccc(Cl)cc2
InChI1S/C13H11ClO/c14-12-8-6-11(7-9-12)13(15)10-4-2-1-3-5-10/h1-9,13,15H
InChI keyAJYOOHCNOXWTKJ-UHFFFAOYSA-N

安全信息

储存分类代码11 - Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
1377010USPMeclizine Related Compound AUnited States Pharmacopeia (USP) Reference Standard11011.4元/15 MG;   展开

产品说明

一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

分析说明

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

其他说明

USP issued SDS can be found here.
Sales restrictions may apply.

基本信息

线性分子式ClC6H4CH(C6H5)OH
分子量218.68
MDL编号MFCD00004491
PubChem化学物质编号329750332
NACRESNA.24

产品性质

等级pharmaceutical primary standard
manufacturer/tradenameUSP
mp58-60 ℃ (lit.)
application(s)pharmaceutical (small molecule)
格式neat
储存温度2-8℃
SMILES stringOC(c1ccccc1)c2ccc(Cl)cc2
InChI1S/C13H11ClO/c14-12-8-6-11(7-9-12)13(15)10-4-2-1-3-5-10/h1-9,13,15H
InChI keyAJYOOHCNOXWTKJ-UHFFFAOYSA-N

安全信息

储存分类代码13 - Non Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
242819Fluorochem(4-Chlorophenyl)(phenyl)methanol95%330元/1g;   968元/25g;   5236元/500g;   展开

基本信息

CAS Number119-56-2
MDL NumberMFCD00004491
Boiling Point151℃
Melting Point61℃

安全信息

图形或危害标志
危险性说明 H302: Harmful if swallowed.
H315: Causes skin irritation.
H319: Causes serious eye irritation.
H332: Harmful if inhaled.
H335: May cause respiratory irritation.
H412: Harmful to aquatic life with long lasting effects.
防范说明 P233: Keep container tightly closed.
P260: Do not breathe .
P261: Avoid breathing .
P264: Wash hands thoroughly after handling.
P270: Do not eat, drink or smoke when using this product.
P271: Use only outdoors or in a well-ventilated area.
P273: Avoid release to the environment.
P280: Wear .
P301 + P312: IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell.
P302 + P352: IF ON SKIN: Wash with plenty of soap and water.
P304: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing..
P304 + P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P312: Call a POISON CENTER or doctor/physician if you feel unwell.
P321: Specific treatment (see relevant procedures. on this label).
P330: Rinse mouth.
P332 + P313: If skin irritation occurs: Get medical advice/ attention.
P337 + P313: If eye irritation persists: Get medical advice/attention.
P340: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P362: Take off contaminated clothing and wash before reuse.
P403: Store in a well-ventilated place.
P403 + P233: Store in a well-ventilated place. Keep container tightly closed.
P405: Store locked up.
P501: Dispose of contents/container to in accordance with local regulation .
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