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CAS: 118288-08-7
中文名称: 
拉夫替丁
(±)-2-[(2-呋喃基甲基)亚硫酰]-N-[4-[4-(1-哌啶基甲基)
英文名称: 
acetamide, 2-((2-furanylmethyl)sulfinyl)-n-(4-((4-(1-piperidinylmethyl)-2-pyrid
(z)-inyl)o xy)- 2-butenyl)
(+-)-2-(furfurylsulfinyl)-n-(4-(4-(piperidinomethyl)-2-pyridyl)oxy-(z)-2 -but
enyl)acetamide
frg-8813
lafutidine
n-(4-(4-piperidinylmethyl)pyridyl-2-oxy)butenyl-2-(furfurylsulfinyl)acet amid
性质描述: 本品为白色至微黄色结晶性粉末,无臭或微有气味,味苦。
推荐供应商
货号品牌产品名称规格包装、参考价格详情
L0341TCILafutidine>98.0%(T)(HPLC)190元/25MG;   990元/250MG;   2690元/1G;   展开

基本信息

纯度/分析方法>98.0%(T)(HPLC)
分子式/分子量C22H29N3O4S = 431.55
外观与形状(20℃)固体
Reaxys-RN8045494
Merck Index (14)5347
MDL编号MFCD00867520

技术规格

AppearanceWhite to Orange to Green powder to crystal
Purity(HPLC)min. 98.0 area%
Purity(Nonaqueous Titration)min. 98.0 %
Melting point97.0 to 101.0 ℃

物性(参考值)

熔点99 ℃
水溶性不溶
溶解性(易溶于)二甲基甲酰胺
溶解性(可溶于)甲醇
溶解度(极微溶)甲醇,乙醚

安全信息

图形或危害标志
信号词警告
危险性说明H302 : 吞咽有害。
防范说明P501 : 将内装物/容器送到批准的废物处理厂处理。
P270 : 使用本产品时不要进食、饮水或吸烟。
P264 : 作业后彻底清洗皮肤。
P301 + P312 + P330 : 如误吞咽:如感觉不适,呼叫急救中心/医生。漱口。

相关法规

RTECS#AC2957000
356680J&KLafutidine99%672元/50MG;   1796元/250MG;   展开

基本信息

分子式C22H29N3O4S
分子量431.55
MDL编码MFCD00867520

安全信息

防范说明P262
SML1611Sigma-AldrichLafutidine≥98% (HPLC)973.81元/10 MG;   2394.05元/50 MG;   展开

产品说明

包装

10, 50 mg in glass bottle

生化/生理作用

Lafutidine is a second generation H2 histamine receptor antagonist. Lafutidine has been used clinically to treat ulcers and gastro-esophageal reflux disease (GERD). Lafutidine has also been investigated as a treatment against peripheral neuropathy and for its protective stomach effects during cancer chemotherapies and long term ibuprofen use.

基本信息

经验(实验)分子式C22H29N3O4S
分子量431.55
MDL编号MFCD00867520
PubChem化学物质编号329825497
NACRESNA.77

产品性质

质量水平100
测定≥98% (HPLC)
形式powder
颜色 white to beige
溶解性DMSO: 20 mg/mL, clear
储存温度−20℃
SMILES stringO=C(CS(CC1=CC=CO1)=O)NC/C=C\COC2=NC=CC(CN3CCCCC3)=C2
InChI1S/C22H29N3O4S/c26-21(18-30(27)17-20-7-6-14-28-20)23-9-2-5-13-29-22-15-19(8-10-24-22)16-25-11-3-1-4-12-25/h2,5-8,10,14-15H,1,3-4,9,11-13,16-18H2,(H,23,26)/b5-2-
InChI keyKMZQAVXSMUKBPD-DJWKRKHSSA-N

安全信息

象形图GHS07
警示用语:Warning
危险声明H302
预防措施声明P301 + P312 + P330
危险分类Acute Tox. 4 Oral
储存分类代码13 - Non Combustible Solids
WGKWGK 1
闪点(F)Not applicable
闪点(C)Not applicable
079405Fluorochem(Z)-2-((Furan-2-ylmethyl)sulfinyl)-N-(4-((3-(piperidin-1-ylmethyl)pyridin-2-yl)oxy)but-2-en-1-yl)acetamide95%5786元/250mg;   14454元/1g;   展开

基本信息

CAS Number118288-08-7
MDL NumberMFCD21607521

安全信息

图形或危害标志
危险性说明 H315: Causes skin irritation.
H319: Causes serious eye irritation.
H335: May cause respiratory irritation.
防范说明 P233: Keep container tightly closed.
P260: Do not breathe .
P261: Avoid breathing .
P264: Wash hands thoroughly after handling.
P271: Use only outdoors or in a well-ventilated area.
P280: Wear .
P302 + P352: IF ON SKIN: Wash with plenty of soap and water.
P304: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing..
P304 + P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P312: Call a POISON CENTER or doctor/physician if you feel unwell.
P321: Specific treatment (see relevant procedures. on this label).
P332 + P313: If skin irritation occurs: Get medical advice/ attention.
P337 + P313: If eye irritation persists: Get medical advice/attention.
P340: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P362: Take off contaminated clothing and wash before reuse.
P403: Store in a well-ventilated place.
P403 + P233: Store in a well-ventilated place. Keep container tightly closed.
P405: Store locked up.
P501: Dispose of contents/container to in accordance with local regulation .
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