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CAS: 118-55-8
分子式: C13H10O3
分子量: 214.22
沸点: 172-173℃
熔点: 40-44℃
中文名称: 
邻羟基苯甲酸苯酯
萨罗
水杨酸苯酯
2-羟基苯甲酸苯酯
英文名称: 
Phenyl 2-hydroxybenzoate
Salicylic acid phenyl ester
Benzoic acid,2-hydroxy-,phenyl ester
2-Hydroxybenzoic acid phenyl ester
Phenylsalicylat
phenylsalicylate
Phenyl salicylate
Benzoic acid, 2-hydroxy-, phenyl ester
Salol
salicylic acid, phenyl ester
2-hydroxy-benzoic aci phenyl ester
fenylester kyseliny salicylove
展开更多英文名
性质描述: 无色结晶粉末,具有愉快的芳香气味(冬青油气味)。密度1.250,熔点43℃,沸点173℃(1.6kPa)。 易溶于乙醚、苯和氯仿,溶于乙醇,几乎不溶于水和甘油。
生产方法: 水杨酸与苯酚在催化剂硫酸存在下进行酯化。酯化液经中和、水洗、蒸馏得成品。原料消耗定额:水杨酸850kg/t、苯酚850kg/t。
用途: 本品为一种紫外线吸收剂,用于塑料制品。但吸收波长范围较窄,光稳定性较差。也用作医药消毒防腐剂和用于有机合成。还用来制香料。
推荐供应商
货号品牌产品名称规格包装、参考价格详情
P815645MACKLIN水杨酸苯酯试剂级, 98%30元/50g;   86元/250g;   278元/1kg;   1260元/5kg;   展开
储存:室温
状态:白色晶体
P815644MACKLIN水杨酸苯酯99.5%40元/100g;   186元/500g;   739元/2.5kg;   1469元/5kg;   展开
储存:室温
状态:白色固体
S0017TCIPhenyl Salicylate>98.0%(GC)165元/25G;   780元/500G;   展开

基本信息

纯度/分析方法>98.0%(GC)
分子式/分子量C13H10O3 = 214.22
外观与形状(20℃)固体
Reaxys-RN393969
PubChem物质ID87575648
SDBS (AIST Spectral DB)2697
Merck Index (14)7310
MDL编号MFCD00002213

技术规格

AppearanceWhite powder to crystal
Purity(GC)min. 98.0 %
Melting point41.0 to 44.0 ℃

物性(参考值)

熔点44 ℃
沸点173 ℃/12 mmHg
水溶性不溶
溶解性(可溶于)丙酮,醇,二噁烷,乙醚,氯仿,苯

安全信息

图形或危害标志
信号词警告
危险性说明H303 : 吞咽可能有害。
H315 : 造成皮肤刺激。
H319 : 造成严重眼刺激。
H401 : 对水生生物有毒。
防范说明P501 : 将内装物/容器送到批准的废物处理厂处理。
P273 : 避免释放到环境中。
P264 : 作业后彻底清洗皮肤。
P280 : 戴防护手套/戴防护眼罩/戴防护面具。
P302 + P352 : 如皮肤沾染:用水充分清洗。
P312 : 如感觉不适,呼叫急救中心/医生。
P337 + P313 : 如仍觉眼刺激:求医/就诊。
P305 + P351 + P338 : 如进入眼睛:用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出,取出隐形眼镜。继续冲洗。
P362+P364 : 脱掉沾污的衣服,清洗后方可重新使用。
P332 + P313 : 如发生皮肤刺激:求医/就诊。

相关法规

RTECS#VO6125000
389459J&KPhenyl Salicylate99%92元/25G;   140元/100G;   416元/500G;   展开

基本信息

分子式C13H10O3
分子量214.22
熔点41-43
沸点172-173
闪点113
MDL编码MFCD00002213
Beilstein393969
Merck14,7310
EINECS 编号204-259-2

安全信息

图形或危害标志
提示语Warning
危险说明H315
H319
H335
防范说明P261
P305+P351+P338
WGK2
RTECSVO6125000
TSCA
B20686Alfa AesarPhenyl Salicylate99%548元/100g;   1397元/500g;   展开

应用
Phenyl salicylate is used in the production of polymers, lacquers, adhesives, waxes and polishes. It acts as an antiseptic and mild analgesic. It is also used in the prevention of sunburn. It reacts with o-toluidine in 1,2,4-trichlorobenzene to give the corresponding amide o-Salicylotoluide. Further, it is involved in the study to check the effect on crystal size with cooling rate in the laboratory. In addition to this, it is used in veterinary medicine and also employed for coating pills, in which the medicine is intended for enteric release salol.

备注
Light sensitive. Incompatible with strong oxidants, strong acids and strong bases. Store in a cool place.

基本信息

MDL
MFCD00002213

EINECS
204-259-2

分子式
C13H10O3

分子量
214.22

熔点
41-45°

沸点
172-174°/12mm

闪点
160°(320°F)

灵敏度
Ambient temperatures.

形态
Crystalline powder

溶解性
Soluble in alcohol, ether, chloroform, turpentine, acetone and benzene. Sparingly soluble in chloroformbenzene. Insoluble in water.

Beilstein
393969

Merck
14,7310

GHS危害和防范说明

GHS符号

Hazard Statements
H303-H315-H319-H335
May be harmful if swallowed.Causes skin irritation.Causes serious eye irritation.May cause respiratory irritation.

Precautionary Statements
P261-P280a-P305+P351+P338-P304+P340-P405-P501a
Avoid breathing dust/fume/gas/mist/vapours/spray.Wear protective gloves and eye/face protection.IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing.Store locked up.Dispose of contents/container in accordance with local/regional/national/international regulations.

安全信息

危险类别
36/37/38
Irritating to eyes, respiratory system and skin.

安全等级
26-37-60
In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.This material and its container must be disposed of as hazardous waste

RTECS
VO6125000

TSCA

C16508Alfa AesarPhenyl Salicylate99%873元/250g;   2514元/1kg;   5199元/2.5kg;   展开

基本信息

Ref#
16508

MDL
2213

分子式
C13 H10 O3

分子量
214.22

闪点
>110

形态
White cryst powder

W396001Sigma-AldrichPhenyl Salicylate≥99%, FG404.65元/;   1016.01元/1 KG;   5582.97元/5 KG;   展开

基本信息

线性分子式2-(HO)C6H4CO2C6H5
分子量214.22
FEMA编号3960
Beilstein393969
EC 号204-259-2
MDL编号MFCD00002213
PubChem化学物质编号24901954
Flavis编号9.689
NACRESNA.21

产品性质

质量水平400
生物来源synthetic
等级FG
agencymeets purity specifications of JECFA
reg. complianceEU Regulation 1334/2008 & 872/2012
FDA 21 CFR 110
测定≥99%
bp172-173 ℃/12 mmHg (lit.)
mp41-43 ℃ (lit.)
文件see Safety & Documentation for available documents
性状检查fruity; sweet
application(s)flavors and fragrances
食品过敏原no known allergens
SMILES stringOc1ccccc1C(=O)Oc2ccccc2
InChI1S/C13H10O3/c14-12-9-5-4-8-11(12)13(15)16-10-6-2-1-3-7-10/h1-9,14H
InChI keyZQBAKBUEJOMQEX-UHFFFAOYSA-N

安全信息

象形图GHS07GHS09
警示用语:Warning
危险声明H315 - H317 - H319 - H411
预防措施声明P261 - P264 - P273 - P280 - P302 + P352 - P305 + P351 + P338
危险分类Aquatic Chronic 2 - Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1
储存分类代码11 - Combustible Solids
WGKWGK 2
闪点(F)230.0 °F - closed cup
闪点(C)110 ℃ - closed cup
个人防护装备dust mask type N95 (US), Eyeshields, Gloves
PHR1152SupelcoPhenyl salicylate melting point standardPharmaceutical Secondary Standard; Certified Reference Material1269.49元/1 G;   展开

产品说明

一般描述

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Phenyl salicylate is a phenyl ester of salicylic acid and is used as a medicine under the name ′salol′ as an internal antiseptic. It finds its application in paints, waxes, and varnishes as it is found to absorb UV radiation in the range of 290-325 nm. It also shows its presence in cosmetics and sunscreens as a UV filter.

应用

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
Phenyl salicylate may be used as an analytical reference standard for the determination of the analyte in pharmaceutical formulations by chromatographic and spectrophotometric techniques.

分析说明

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

其他说明

Values of analytes vary lot to lot.
This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

附注

To see an example of a Certificate of Analysis for this material enter LRAA7176 in the slot below. This is an example certificate only and may not be the lot that you receive.

基本信息

线性分子式2-(HO)C6H4CO2C6H5
分子量214.22
Beilstein393969
EC 号204-259-2
MDL编号MFCD00002213
PubChem化学物质编号329823170
NACRESNA.24

产品性质

质量水平300
等级certified reference material
pharmaceutical secondary standard
CofAcurrent certificate can be downloaded
technique(s)HPLC: suitable
gas chromatography (GC): suitable
bp172-173 ℃/12 mmHg (lit.)
mp~Approximately 42 ℃
41-43 ℃ (lit.)
application(s)pharmaceutical (small molecule)
格式neat
药典可追溯性traceable to USP 1534209
储存温度2-30℃
SMILES stringOc1ccccc1C(=O)Oc2ccccc2
InChI1S/C13H10O3/c14-12-9-5-4-8-11(12)13(15)16-10-6-2-1-3-7-10/h1-9,14H
InChI keyZQBAKBUEJOMQEX-UHFFFAOYSA-N

安全信息

象形图GHS07GHS09
警示用语:Warning
危险声明H315 - H317 - H319 - H411
预防措施声明P261 - P264 - P273 - P280 - P302 + P352 - P305 + P351 + P338
危险分类Aquatic Chronic 2 - Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1
储存分类代码11 - Combustible Solids
WGKWGK 2
闪点(F)230.0 °F - closed cup
闪点(C)110 ℃ - closed cup
1534209USPPhenyl salicylate melting point standardapproximately 41 degrees, United States Pharmacopeia (USP) Reference Standard2109.6元/1 G;   展开

产品说明

一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

应用

Phenyl salicylate melting point standard may be used as a calorimetric reference material to investigate its melting behavior by studying its high-resolution specific enthalpy and specific heat capacity using adiabatic scanning calorimetry.

分析说明

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

其他说明

USP issued SDS can be found here.
Sales restrictions may apply.

基本信息

线性分子式2-(HO)C6H4CO2C6H5
分子量214.22
Beilstein393969
MDL编号MFCD00002213
PubChem化学物质编号329750824
NACRESNA.24

产品性质

等级pharmaceutical primary standard
质量approximately 41 degrees
manufacturer/tradenameUSP
bp172-173 ℃/12 mmHg (lit.)
mp41-43 ℃ (lit.)
application(s)pharmaceutical (small molecule)
格式neat
储存温度2-8℃
SMILES stringOc1ccccc1C(=O)Oc2ccccc2
InChI1S/C13H10O3/c14-12-9-5-4-8-11(12)13(15)16-10-6-2-1-3-7-10/h1-9,14H
InChI keyZQBAKBUEJOMQEX-UHFFFAOYSA-N

安全信息

象形图GHS07GHS09
警示用语:Warning
危险声明H315 - H317 - H319 - H411
预防措施声明P261 - P264 - P273 - P280 - P302 + P352 - P305 + P351 + P338
危险分类Aquatic Chronic 2 - Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1
储存分类代码11 - Combustible Solids
WGKWGK 2
闪点(F)230.0 °F - closed cup
闪点(C)110 ℃ - closed cup
44770SupelcoMettler-Toledo Calibration substance ME 30034252, Phenyl salicylatetraceable to primary standards1230.31元/5 G;   展开

产品说明

一般描述

Phenyl salicylate is a carboxylic acid phenyl ester, known for its aroma and flavoring properties. It finds application in foods and consumer products, medicines and as a UV filter.
Mettler-Toledo calibration substance ME 30034252, phenyl salicylate is an analytical standard, intended for use in the regular calibration of Mettler-Toledo melting point instrument. Its melting point value is an average of 6 to 12 iterations with a Mettler-Toledo MP70 Excellence instrument that is calibrated against primary standards. The melting point is measured using Capillary method in conformance with European Pharmacopeia (2.2.14.)

应用

Vanillin Mettler-Toledo calibration substance ME 51143093 is used to calibrate Mettler-Toledo melting point instruments.

特点和优势

  • Available in a ready-to-use bottle as a finely ground powder
  • Melting point calibration standard traceable to a primary standard (LGC, London)
  • Melting point evaluation conducted in both thermodynamic and pharmacopeia modes for physically correct and heating rate dependent melting point determinations, respectively
  • Provided with certificates of analysis and safety sata sheet
  • A product of analytical standard grade to help meet the QC/QA requirements of melting point determination
  • Standard deviation up to ± 0.2 ℃

基本信息

线性分子式2-(HO)C6H4CO2C6H5
分子量214.22
Beilstein393969
EC 号204-259-2
MDL编号MFCD00002213
PubChem化学物质编号329756543

产品性质

等级analytical standard
质量水平100
保质期limited shelf life, expiry date on the label
bp172-173 ℃/12 mmHg (lit.)
mp41-43 ℃ (lit.)
application(s)food and beverages
pharmaceutical
格式neat
SMILES stringOc1ccccc1C(=O)Oc2ccccc2
InChI1S/C13H10O3/c14-12-9-5-4-8-11(12)13(15)16-10-6-2-1-3-7-10/h1-9,14H
InChI keyZQBAKBUEJOMQEX-UHFFFAOYSA-N

安全信息

象形图GHS07GHS09
警示用语:Warning
危险声明H315 - H317 - H319 - H411
预防措施声明P261 - P264 - P273 - P280 - P302 + P352 - P305 + P351 + P338
危险分类Aquatic Chronic 2 - Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1
储存分类代码11 - Combustible Solids
WGKWGK 2
闪点(F)230.0 °F - closed cup
闪点(C)110 ℃ - closed cup
358219FluorochemPhenyl 2-Hydroxybenzoate0.97220元/100g;   展开

基本信息

CAS Number118-55-8
MDL NumberMFCD00002213
Boiling Point173℃
Melting Point44℃

安全信息

图形或危害标志
危险性说明 EUH401: To avoid risks to human health and the environment, comply with the instructions for use.
H302: Harmful if swallowed.
H315: Causes skin irritation.
H319: Causes serious eye irritation.
H332: Harmful if inhaled.
H335: May cause respiratory irritation.
防范说明 P233: Keep container tightly closed.
P260: Do not breathe .
P261: Avoid breathing .
P264: Wash hands thoroughly after handling.
P270: Do not eat, drink or smoke when using this product.
P271: Use only outdoors or in a well-ventilated area.
P280: Wear .
P301 + P312: IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell.
P302 + P352: IF ON SKIN: Wash with plenty of soap and water.
P304: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing..
P304 + P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P312: Call a POISON CENTER or doctor/physician if you feel unwell.
P321: Specific treatment (see relevant procedures. on this label).
P330: Rinse mouth.
P332 + P313: If skin irritation occurs: Get medical advice/ attention.
P337 + P313: If eye irritation persists: Get medical advice/attention.
P340: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P362: Take off contaminated clothing and wash before reuse.
P403: Store in a well-ventilated place.
P403 + P233: Store in a well-ventilated place. Keep container tightly closed.
P405: Store locked up.
P501: Dispose of contents/container to in accordance with local regulation .
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