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CAS: 118-12-7
分子式: C12H15N
分子量: 173.26
沸点: 248 °C(lit.)
熔点: -8 °C
中文名称: 
1,3,3-三甲基-2-亚甲基2,3-二氢吲哚
2,3-二氢-1,3,3-三甲基-2-亚甲基-1H-吲哚
三贝斯
1,3,3-三甲基-2-亚甲基吲哚啉
2-亚甲基-1,3,3-三甲基二氢吲哚
2-亚甲基-1,3,3-三甲基吲哚啉
英文名称: 
2,3-Dihydro-1,3,3-trimethyl-2-methyleneindoline
2,3-dihydro-1,3,3-trimethyl-2-methylene-1H-Indole
2-methylene-1,3,3-trimethyl-indolin
1,3,3-trimethyl-2-methyleneindoline
2,3-dihydro-1,3,3-trimethyl-2-methylene-1h-indol
2-methylene-1,3,3-trimethylindoline
fischer base
fischer's base
fischer's methylene base
1,3,3-trimethyl-2-methylene-indolin
2-Methylene-1,3,3,-trimethylindoline
1H-Indole,2,3-dihydro-1,3,3-trimethyl-2-methylene-
展开更多英文名
性质描述: 油状液体。97%的工业品的沸点为248℃,相对密度0.979,折光率1.5780,闪点101℃。
生产方法: 由苯肼与甲乙酮经缩合、闭环反应后,用甲苯磺酸甲酯进行甲基化,再用氨水中和而制得。将水、苯肼、硫酸投入反应锅,加热至80℃,滴加甲乙酮,加料温度控制在80-90℃。加毕,在90-100℃继续反应1.5h。冷至70℃,加入二甲苯,静置分去下层水,二甲苯层再用水洗一次。加入对甲苯磺酸甲酯,加热,在155-160℃反应3h,再在160-165℃反应3h,将反应物料在水中稀释,在70-90℃滴加20%氨水至pH值大于8。静置分层,将上层油层进行减压蒸馏,收集80℃(1.33-2.67kPa)以上馏分即为成品。收率约70%。
用途: 该品可作染料中间体,用于制造阳离子金黄X-GL、阳离子桃红FG、阳离子艳红5-GN、阳离子红6B、阳离子大红3GL等。
推荐供应商
货号品牌产品名称规格包装、参考价格详情
T819193MACKLIN1,3,3-三甲基-2-亚甲基吲哚啉97%37元/5g;   94元/25g;   303元/100g;   1379元/500g;   展开
储存:室温
状态:红色液体
折射率:n20/D 1.577(lit.)
T0879TCI1,3,3-Trimethyl-2-methyleneindoline>96.0%(GC)280元/25ML;   465元/100ML;   1595元/500ML;   展开

基本信息

纯度/分析方法>96.0%(GC)
分子式/分子量C12H15N = 173.26
外观与形状(20℃)液体
Reaxys-RN131162
PubChem物质ID87576707
SDBS (AIST Spectral DB)7099
MDL编号MFCD00005813

技术规格

AppearanceRed to Dark red to Brown clear liquid
Purity(GC)min. 96.0 %

物性(参考值)

熔点-10 ℃
沸点248 ℃
闪点101 ℃
比重0.98
折射率1.58

安全信息

图形或危害标志
信号词警告
危险性说明H302 : 吞咽有害。
H315 : 造成皮肤刺激。
H319 : 造成严重眼刺激。
H410 : 对水生生物毒性极大并具有长期持续影响。
防范说明P501 : 将内装物/容器送到批准的废物处理厂处理。
P273 : 避免释放到环境中。
P270 : 使用本产品时不要进食、饮水或吸烟。
P264 : 作业后彻底清洗皮肤。
P280 : 戴防护手套/戴防护眼罩/戴防护面具。
P302 + P352 : 如皮肤沾染:用水充分清洗。
P391 : 收集溢出物。
P337 + P313 : 如仍觉眼刺激:求医/就诊。
P305 + P351 + P338 : 如进入眼睛:用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出,取出隐形眼镜。继续冲洗。
P362+P364 : 脱掉沾污的衣服,清洗后方可重新使用。
P332 + P313 : 如发生皮肤刺激:求医/就诊。
P301 + P312 + P330 : 如误吞咽:如感觉不适,呼叫急救中心/医生。漱口。

相关法规

RTECS#NM1926500

运输信息

UN编号UN3082
类别9
包装类别 III
监管条件代码(*)
216624J&K1,3,3-Trimethyl-2-methyleneindoline95%206元/25ML;   461元/100ML;   1987元/500ML;   展开

基本信息

分子式C12H15N
分子量173.26
熔点-8
沸点248
闪点63
密度0.979
折光率(n20D)1.5760 - 1.5780
MDL编码MFCD00005813
Beilstein131162
EINECS 编号204-235-1

安全信息

图形或危害标志
提示语Warning
危险说明H302
H315
H400
防范说明P273
UN号码3082
危险分类9
包装等级III
WGK2
RTECSNM1926500
A16741Alfa Aesar1,3,3-Trimethyl-2-methyleneindoline95%1683元/50g;   4502元/250g;   展开

基本信息

MDL
MFCD00005813

EINECS
204-235-1

分子式
C12H15N

分子量
173.26

熔点
-10°

沸点
247-248°

闪点
101°(213°F)

密度
0.979

折射率
1.5780

灵敏度
Ambient temperatures.

形态
Liquid

Beilstein
131162

GHS危害和防范说明

GHS符号

Hazard Statements
H315-H319-H335
Causes skin irritation.Causes serious eye irritation.May cause respiratory irritation.

Precautionary Statements
P261-P280a-P305+P351+P338-P304+P340-P405-P501a
Avoid breathing dust/fume/gas/mist/vapours/spray.Wear protective gloves and eye/face protection.IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing.Store locked up.Dispose of contents/container in accordance with local/regional/national/international regulations.

安全信息

危险类别
36/37/38
Irritating to eyes, respiratory system and skin.

安全等级
26-37
In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.

RTECS
NM1926500

TSCA

M46209Sigma-Aldrich1,3,3-Trimethyl-2-methyleneindoline97%1332.99元/100 G;   展开

产品说明

应用

用于以下反应的反应物:

  • 环加成反应
  • 红色光致变色染料的制备
  • 通过开环易位聚合反应合成光致变色均聚物

包装

5, 100 g in glass bottle

基本信息

经验(实验)分子式C12H15N
分子量173.25
Beilstein131162
EC 号204-235-1
MDL编号MFCD00005813
PubChem化学物质编号24896929
NACRESNA.22

产品性质

质量水平200
测定97%
折射率n20/D 1.577 (lit.)
bp248 ℃ (lit.)
密度0.979 g/mL at 25 ℃ (lit.)
SMILES stringCN1C(=C)C(C)(C)c2ccccc12
InChI1S/C12H15N/c1-9-12(2,3)10-7-5-6-8-11(10)13(9)4/h5-8H,1H2,2-4H3
InChI keyZTUKGBOUHWYFGC-UHFFFAOYSA-N

安全信息

象形图GHS07GHS09
警示用语:Warning
危险声明H302 - H400
预防措施声明P273 - P301 + P312 + P330
危险分类Acute Tox. 4 Oral - Aquatic Acute 1
储存分类代码10 - Combustible liquids
WGKWGK 2
闪点(F)145.4 °F - closed cup
闪点(C)63 ℃ - closed cup
个人防护装备Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter
214586Fluorochem1,3,3-Trimethyl-2-methyleneindoline95%220元/1g;   506元/25ml;   1188元/100ml;   3608元/500ml;   展开

基本信息

CAS Number118-12-7
MDL NumberMFCD00005813
Boiling Point248℃
Melting Point-8℃
Density0.979

安全信息

图形或危害标志
危险性说明 H302: Harmful if swallowed.
H315: Causes skin irritation.
H319: Causes serious eye irritation.
H335: May cause respiratory irritation.
H410: Very toxic to aquatic life with long lasting effects.
防范说明 P233: Keep container tightly closed.
P260: Do not breathe .
P261: Avoid breathing
P264: Wash hands thoroughly after handling.
P270: Do not eat, drink or smoke when using this product.
P271: Use only outdoors or in a well-ventilated area.
P273: Avoid release to the environment.
P280: Wear .
P301 + P312: IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell.
P302 + P352: IF ON SKIN: Wash with plenty of soap and water.
P304: IF INHALED: .
P304 + P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P312: Call a POISON CENTER or doctor/physician if you feel unwell.
P321: Specific treatment (see . on this label).
P330: Rinse mouth.
P332 + P313: If skin irritation occurs: Get medical advice/ attention.
P337 + P313: If eye irritation persists: Get medical advice/attention.
P340: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P362: Take off contaminated clothing and wash before reuse.
P391: Collect spillage.
P403: Store in a well-ventilated place.
P403 + P233: Store in a well-ventilated place. Keep container tightly closed.
P405: Store locked up.
P501: Dispose of contents/container to local regulations.
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