CAS 114-07-8; 红霉素; Erythromycin

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E728823

MACKLIN

红霉素标准溶液

1 mg/mL in H2O

502元/10ml;

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储存：2-8°C
折射率：-74 ° (C=2, EtOH)

E728824

MACKLIN

红霉素

10mM in DMSO

475元/1ml;

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储存：-20°C
折射率：-74 ° (C=2, EtOH)

E808820

MACKLIN

红霉素

98%

32元/1g; 55元/5g; 140元/25g; 530元/100g; 1799元/500g;

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储存：室温
状态：白色到灰白色固体
折射率：-74 ° (C=2, EtOH)

E808819

MACKLIN

红霉素

USP/EP

102元/5g; 266元/25g; 798元/100g;

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储存：室温
状态：白色到灰白色固体
折射率：-74 ° (C=2, EtOH)

E6036

MACKLIN

红霉素

生物技术级

92元/5g; 242元/25g;

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储存：室温,阴凉
状态：白色-淡黄色晶体-粉末
折射率：-74 ° (C=2, EtOH)

359681

J&K

Erythromycin

88%, 效价: ≥920 u/mg

242元/5G; 570元/25G;

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基本信息

分子式	C₃₇H₆₇NO₁₃
分子量	733.93
熔点	133
MDL编码	MFCD00084654
Beilstein	75279
EINECS 编号	204-040-1

安全信息

防范说明	P262
WGK	3
RTECS	KF437500

R10954

Alfa Aesar

Erythromycin Standard solution

100ppm

168元/1ml;

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安全信息

危险等级
3

R12011

Alfa Aesar

Erythromycin; Erythromycin A,1000ppm

352元/1ml;

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安全信息

危险等级
3

E5389

Sigma-Aldrich

Erythromycin

BioReagent, suitable for cell culture

168.37元/1 G; 535.62元/5 G;

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产品说明

一般描述

Chemical structure: macrolide
Erythromycin is an antibiotic produced by growth of certain strains of Streptomyces erythreus. This product is composed largely of erythromycin A with small amounts of erythromycins B and C and is recommended for concentration at 100 mg/L. Concentrations between 50 and 200 mg/L have also proven effective in controlling bacterial growth. Erythromycin has been used as a motilin receptor agonist, to block respiratory glycoconjugate secretion in human airways in vitro, and for selecting plasmid-cured and recombinant lactococcus lactis MG1363 strains.

应用

Erythromycin has been used:

as a supplement for nutrient broth medium for culturing green fluorescent protein (GFP)- expressing E. coli
as a model drug to determine small intestinal (SMI) microtissue viability using the MTT assay{254
as an antibiotic to study the treatment strategies of chronic infections

包装

1, 5 g in poly bottle

生化/生理作用

作用机制: 红霉素通过在转肽步骤中抑制延伸起作用，特别是通过结合细菌70S rRNA复合物的50S亚单位来抑制氨酰从A位点到P位点的易位。
抗菌谱：该产品可以抗革兰氏阴性和革兰氏阳性细菌。

注意

This product is stable in solution at 37℃ for 3 days. Stock solutions should be stored at 2-8℃.

制备说明

This product is soluble in water at 2 mg/mL, with a 0.067% solution in water yielding a pH of 8.0-10.5. It is also soluble in ethanol at 50 mg/mL, yielding a clear, colorless to faint yellow solution. It is freely soluble in alcohol, acetone, chloroform, acetonitrile and ethyl acetate but forms salts with acids. All solutions should be protected from light.

基本信息

经验(实验)分子式	C₃₇H₆₇NO₁₃
分子量	733.93
Beilstein	75279
EC 号	204-040-1
MDL编号	MFCD00084654
PubChem化学物质编号	24894612
NACRES	NA.76

产品性质

质量水平	200
产品线	BioReagent
形式	powder
效能	≥850 μg per mg
technique(s)	cell culture \| mammalian: suitable
杂质	≤0.1 EU/mg endotoxin
颜色	white
mp	133 ℃
溶解性	2 M HCl: 50 mg/mL (Stock solutions should be stored at 2-8 ℃. Stable at 37 ℃ for 3 days.) ethanol: soluble (Stock solutions should be stored at 2-8 ℃. Stable at 37 ℃ for 3 days.)
抗生素抗菌谱	Gram-negative bacteria Gram-positive bacteria
作用机制	protein synthesis \| interferes
SMILES string	CC[C@H]1OC(=O)[C@H](C)[C@@H](O[C@H]2C[C@@](C)(OC)[C@@H](O)[C@H](C)O2)[C@H](C)[C@@H](O[C@@H]3O[C@H](C)C[C@@H]([C@H]3O)N(C)C)[C@](C)(O)C[C@@H](C)C(=O)[C@H](C)[C@@H](O)[C@]1(C)O
InChI	1S/C37H67NO13/c1-14-25-37(10,45)30(41)20(4)27(39)18(2)16-35(8,44)32(51-34-28(40)24(38(11)12)15-19(3)47-34)21(5)29(22(6)33(43)49-25)50-26-17-36(9,46-13)31(42)23(7)48-26/h18-26,28-32,34,40-42,44-45H,14-17H2,1-13H3/t18-,19-,20+,21+,22-,23+,24+,25-,26+,28-,29+,30-,31+,32-,34+,35-,36-,37-/m1/s1
InChI key	ULGZDMOVFRHVEP-RWJQBGPGSA-N
Gene Information	human ... ABCB1(5243), CYP3A4(1576), MLNR(2862) mouse ... Abcb1a(18671), Abcb1b(18669)

安全信息

储存分类代码	13 - Non Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable
个人防护装备	Eyeshields, Gloves, type N95 (US)

E6376

Sigma-Aldrich

Erythromycin

potency: ≥850 μg per mg

3402.95元/25 G; 6680.25元/100 G;

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产品说明

一般描述

化学结构：大环内酯

包装

25, 100 g in poly bottle

应用

应用
红霉素是一种抗生素，是通过 红霉素链霉菌的某些菌株的生长而产生的。该产品主要由红霉素A和少量红霉素B和C组成，推荐浓度为100 mg/L. 50至200mg/L的浓度范围也被证明可有效控制细菌的生长。红霉素已被用作胃动素受体激动剂，以在体外阻断人气道中的呼吸糖结合物分泌， 并可用于质粒固化重组乳酸链球菌MG1363菌株的选择。

生化/生理作用

注意

该产品在37℃下在溶液中可保持稳定3天。储备溶液应储存在2-8℃。

制备说明

该产品可以2mg/mL的浓度溶于水中，0.067％的水溶液的pH值为8.0-10.5。它也可以50mg/mL的浓度溶于乙醇中，获得澄清、无色至淡黄色的溶液。它易溶于醇、丙酮、氯仿、乙腈和乙酸乙酯中，但会与酸形成盐。所有溶液应保证避光。

基本信息

经验(实验)分子式	C₃₇H₆₇NO₁₃
分子量	733.93
Beilstein	75279
EC 号	204-040-1
MDL编号	MFCD00084654
PubChem化学物质编号	24894626
NACRES	NA.76

产品性质

质量水平	200
生物来源	Streptomyces erythreus
形式	powder
效能	≥850 μg per mg
颜色	white
溶解性	ethanol: 50 mg/mL, clear to slightly hazy, colorless to faintly yellow
作用机制	protein synthesis \| interferes
抗生素抗菌谱	Gram-negative bacteria Gram-positive bacteria
SMILES string	CC[C@H]1OC(=O)[C@H](C)[C@@H](O[C@H]2C[C@@](C)(OC)[C@@H](O)[C@H](C)O2)[C@H](C)[C@@H](O[C@@H]3O[C@H](C)C[C@@H]([C@H]3O)N(C)C)[C@](C)(O)C[C@@H](C)C(=O)[C@H](C)[C@@H](O)[C@]1(C)O
InChI	1S/C37H67NO13/c1-14-25-37(10,45)30(41)20(4)27(39)18(2)16-35(8,44)32(51-34-28(40)24(38(11)12)15-19(3)47-34)21(5)29(22(6)33(43)49-25)50-26-17-36(9,46-13)31(42)23(7)48-26/h18-26,28-32,34,40-42,44-45H,14-17H2,1-13H3/t18-,19-,20+,21+,22-,23+,24+,25-,26+,28-,29+,30-,31+,32-,34+,35-,36-,37-/m1/s1
InChI key	ULGZDMOVFRHVEP-RWJQBGPGSA-N
Gene Information	human ... ABCB1(5243), CYP3A4(1576), MLNR(2862) mouse ... Abcb1a(18671), Abcb1b(18669)

安全信息

储存分类代码	11 - Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable
个人防护装备	Eyeshields, Gloves, type N95 (US)

E0774

Sigma-Aldrich

Erythromycin

meets USP testing specifications

746.73元/5 G; 2228.64元/25 G; 5421.66元/100 G;

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产品说明

一般描述

Chemical structure: macrolide

包装

5, 25, 100 g in poly bottle

应用

Erythromycin is an antibiotic produced by growth of certain strains of Streptomyces erythreus. This product is composed largely of erythromycin A with small amounts of erythromycins B and C and is recommended for concentration at 100 mg/L. Concentrations between 50 and 200 mg/L have also proven effective in controlling bacterial growth. Erythromycin has been used as a motilin receptor agonist, to block respiratory glycoconjugate secretion in human airways in vitro, and for selecting plasmid-cured and recombinant lactococcus lactis MG1363 strains.

生化/生理作用

作用机制: 红霉素通过在转肽步骤中抑制延伸起作用，特别是通过结合细菌70S rRNA复合物的50S亚单位来抑制氨酰从A位点到P位点的易位。

抗菌谱：该产品可以抗革兰氏阴性和革兰氏阳性细菌。

注意

This product is stable in solution at 37℃ for 3 days. Stock solutions should be stored at 2-8℃.

制备说明

基本信息

经验(实验)分子式	C₃₇H₆₇NO₁₃
分子量	733.93
Beilstein	75279
EC 号	204-040-1
MDL编号	MFCD00084654
PubChem化学物质编号	24894374
NACRES	NA.76

产品性质

质量水平	200
agency	USP/NF meets USP testing specifications
形式	solid
旋光性	[α]/D -78 to --71°
溶解性	ethanol: 50 mg/mL, clear to slightly hazy, colorless to faintly yellow
抗生素抗菌谱	Gram-negative bacteria Gram-positive bacteria
application(s)	pharmaceutical (small molecule)
作用机制	protein synthesis \| interferes
SMILES string	CC[C@H]1OC(=O)[C@H](C)[C@@H](O[C@H]2C[C@@](C)(OC)[C@@H](O)[C@H](C)O2)[C@H](C)[C@@H](O[C@@H]3O[C@H](C)C[C@@H]([C@H]3O)N(C)C)[C@](C)(O)C[C@@H](C)C(=O)[C@H](C)[C@@H](O)[C@]1(C)O
InChI	1S/C37H67NO13/c1-14-25-37(10,45)30(41)20(4)27(39)18(2)16-35(8,44)32(51-34-28(40)24(38(11)12)15-19(3)47-34)21(5)29(22(6)33(43)49-25)50-26-17-36(9,46-13)31(42)23(7)48-26/h18-26,28-32,34,40-42,44-45H,14-17H2,1-13H3/t18-,19-,20+,21+,22-,23+,24+,25-,26+,28-,29+,30-,31+,32-,34+,35-,36-,37-/m1/s1
InChI key	ULGZDMOVFRHVEP-RWJQBGPGSA-N
Gene Information	human ... ABCB1(5243), CYP3A4(1576), MLNR(2862) mouse ... Abcb1a(18671), Abcb1b(18669)

安全信息

储存分类代码	13 - Non Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable