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CAS: 1124-11-4
分子式: C8H12N2
分子量: 136.19
沸点: 190℃
熔点: 82-86℃
中文名称: 
磷酸川芎嗪
四甲基吡嗪磷酸盐
川芎嗪一号碱
2,3,5,6-四甲基吡嗪
川芎嗪
四甲基吡嗪
2,3,5,6-四甲基哌嗪
英文名称: 
tetramethyl-Pyrazine
Tetramethylpyrazine
2,3,5,6-Tetramethylpyrazine
2,3,5,6-tetramethyl pyrazine
tetramethyl-pyrazin
Pyrazine,tetramethyl-
Ligustrazine
Ligustrazine phosphate
用途: 抗凝血药,用于闭塞性脑血管疾病。
推荐供应商
货号品牌产品名称规格包装、参考价格详情
T915104MACKLIN2,3,5,6-四甲基吡嗪三水合物99%45元/25g;   125元/100g;   450元/500g;   展开
储存:室温
状态:白色-略淡红黄色晶体-粉末
T819555MACKLIN2,3,5,6-四甲基吡嗪98%48元/25g;   128元/100g;   465元/500g;   2300元/2.5kg;   展开
储存:室温
状态:白色晶体或晶体粉末
T0972TCI2,3,5,6-Tetramethylpyrazine>98.0%(GC)(T)495元/25G;   展开

基本信息

纯度/分析方法>98.0%(GC)(T)
分子式/分子量C8H12N2 = 136.20
外观与形状(20℃)固体
Reaxys-RN113100
PubChem物质ID87576784
SDBS (AIST Spectral DB)6213
MDL编号MFCD00006146

技术规格

AppearanceWhite to Light yellow to Light orange powder to crystal
Purity(GC)min. 98.0 %
Purity(Nonaqueous Titration)min. 98.0 %
Melting point85.0 to 87.0 ℃

物性(参考值)

熔点86 ℃
沸点190 ℃

安全信息

图形或危害标志
信号词警告
危险性说明H302 : 吞咽有害。
H315 : 造成皮肤刺激。
H319 : 造成严重眼刺激。
防范说明P501 : 将内装物/容器送到批准的废物处理厂处理。
P270 : 使用本产品时不要进食、饮水或吸烟。
P264 : 作业后彻底清洗皮肤。
P280 : 戴防护手套/戴防护眼罩/戴防护面具。
P302 + P352 : 如皮肤沾染:用水充分清洗。
P337 + P313 : 如仍觉眼刺激:求医/就诊。
P305 + P351 + P338 : 如进入眼睛:用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出,取出隐形眼镜。继续冲洗。
P362+P364 : 脱掉沾污的衣服,清洗后方可重新使用。
P332 + P313 : 如发生皮肤刺激:求医/就诊。
P301 + P312 + P330 : 如误吞咽:如感觉不适,呼叫急救中心/医生。漱口。

相关法规

RTECS#UQ3905000
210926J&K2,3,5,6-Tetramethylpyrazine98%60元/5G;   135元/25G;   405元/100G;   展开

基本信息

分子式C8H12N2
分子量136.19
熔点77-80
沸点190
闪点78
MDL编码MFCD00006146
Beilstein113100
EINECS 编号214-391-2

安全信息

图形或危害标志
提示语Warning
危险说明H302
防范说明P280
P301+P312
WGK3
RTECSUQ3905000
TSCA
939974J&K2,3,5,6-Tetramethylpyrazine98%, 来源于川芎759元/250MG;   2278元/1G;   展开

基本信息

分子式C8H12N2
分子量136.19
熔点77-80
沸点190
MDL编码MFCD00006146
Beilstein113100
EINECS 编号214-391-2

安全信息

图形或危害标志
提示语Warning
危险说明H302
防范说明P280
P301+P312
WGK3
RTECSUQ3905000
TSCA
A18279Alfa Aesar2,3,5,6-Tetramethylpyrazine98+%636元/25g;   1546元/100g;   展开

应用
2,3,5,6-Tetramethylpyrazine is an anti-inflammatory compound isolated from the fermented food natto. It demonstrated in vivo nootropic activity in rats. It is useful in the treatment of several disorders such as asthma, heart failure, rhinitis and urinary incontinence. It is a flavor ingredient of tobacco. It forms cocrystal with 4-hydroxybenzoic acid which exhibits supramolecular synthon polymorphism.

备注
Stable under recommended storage conditions. Incompatible with oxidizing agents.

基本信息

MDL
MFCD00006146

EINECS
214-391-2

分子式
C8H12N2

分子量
136.20

熔点
83-86°

沸点
190°

密度
1.08

灵敏度
Ambient temperatures.

形态
Crystalline powder

溶解性
Soluble in water (4 g/L at 20°C).

Beilstein
113100

GHS危害和防范说明

GHS符号

Hazard Statements
H301-H315-H319-H335
Toxic if swallowed.Causes skin irritation.Causes serious eye irritation.May cause respiratory irritation.

Precautionary Statements
P261-P280a-P301+P310a-P305+P351+P338-P405-P501a
Avoid breathing dust/fume/gas/mist/vapours/spray.Wear protective gloves and eye/face protection.Wear protective gloves and eye/face protection.IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.Store locked up.Dispose of contents/container in accordance with local/regional/national/international regulations.

安全信息

危险类别
22-36/37/38
Harmful if swallowed.Irritating to eyes, respiratory system and skin.

安全等级
26-36/37
In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.Wear suitable protective clothing and gloves.

欧盟危险品标志

RTECS
UQ3905000

TSCA

W323713Sigma-Aldrich2,3,5,6-Tetramethylpyrazinenatural, ≥98%, FG433.21元/;   2784.87元/100 G;   21104.7元/1 KG;   展开

产品说明

一般描述

2,3,5,6-Tetramethylpyrazine is one of the main volatile aroma compounds in roasted cocoa beans and maple syrup.

包装

100 g in poly bottle
1 kg in poly bottle

基本信息

经验(实验)分子式C8H12N2
分子量136.19
FEMA编号3237
Beilstein113100
EC 号214-391-2
MDL编号MFCD00006146
PubChem化学物质编号24901576
Flavis编号14.018

产品性质

质量水平400
等级FG
Halal
Kosher
natural
agencyfollows IFRA guidelines
meets purity specifications of JECFA
reg. complianceEU Regulation 1223/2009
EU Regulation 1334/2008 & 178/2002
测定≥98%
杂质≤2.0% water (Karl Fischer)
bp190 ℃ (lit.)
mp77-80 ℃ (lit.)
文件see Safety & Documentation for available documents
性状检查chocolate; coffee; fatty; musty; nutty
application(s)flavors and fragrances
食品过敏原no known allergens
致敏芳香化合物no known allergens
SMILES stringCc1nc(C)c(C)nc1C
InChI1S/C8H12N2/c1-5-6(2)10-8(4)7(3)9-5/h1-4H3
InChI keyFINHMKGKINIASC-UHFFFAOYSA-N

安全信息

象形图GHS07
警示用语:Warning
危险声明H302 - H315 - H319 - H335
预防措施声明P261 - P264 - P270 - P301 + P312 - P302 + P352 - P305 + P351 + P338
危险分类Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官Respiratory system
储存分类代码11 - Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
个人防护装备dust mask type N95 (US), Eyeshields, Gloves
W323705Sigma-Aldrich2,3,5,6-Tetramethylpyrazine≥98%, FG404.65元/;   1112.72元/250 G;   2995.92元/1 KG;   11672.3元/5 KG;   展开

基本信息

经验(实验)分子式C8H12N2
分子量136.19
FEMA编号3237
Beilstein113100
EC 号214-391-2
欧洲委员会编号734
MDL编号MFCD00006146
PubChem化学物质编号24901575
Flavis编号14.018

产品性质

质量水平400
生物来源synthetic
等级FG
Halal
Kosher
agencyfollows IFRA guidelines
meets purity specifications of JECFA
reg. complianceEU Regulation 1223/2009
EU Regulation 1334/2008 & 178/2002
测定≥98%
bp190 ℃ (lit.)
mp77-80 ℃ (lit.)
文件see Safety & Documentation for available documents
性状检查chocolate; coffee; fatty; musty; nutty
application(s)flavors and fragrances
食品过敏原no known allergens
致敏芳香化合物no known allergens
SMILES stringCc1nc(C)c(C)nc1C
InChI1S/C8H12N2/c1-5-6(2)10-8(4)7(3)9-5/h1-4H3
InChI keyFINHMKGKINIASC-UHFFFAOYSA-N

安全信息

象形图GHS07
警示用语:Warning
危险声明H302 - H315 - H319 - H335
预防措施声明P261 - P264 - P270 - P301 + P312 - P302 + P352 - P305 + P351 + P338
危险分类Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官Respiratory system
储存分类代码11 - Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
个人防护装备dust mask type N95 (US), Eyeshields, Gloves
183938Sigma-Aldrich2,3,5,6-Tetramethylpyrazine98%649.75元/25 G;   1822.16元/100 G;   展开

产品说明

一般描述

2,3,5,6-四甲基吡嗪是从麻黄中分离得到的。它可用于治疗多种疾病,如哮喘、心力衰竭、鼻炎和尿失禁。它是烟草的一种香味成分。其与 4-羟基苯甲酸形成共晶,表现出超分子合成子多晶型。

包装

25, 100 g in poly bottle

基本信息

经验(实验)分子式C8H12N2
分子量136.19
Beilstein113100
EC 号214-391-2
MDL编号MFCD00006146
eCl@ss39161809
PubChem化学物质编号24851081
NACRESNA.22

产品性质

质量水平100
测定98%
bp190 ℃ (lit.)
mp77-80 ℃ (lit.)
SMILES stringCc1nc(C)c(C)nc1C
InChI1S/C8H12N2/c1-5-6(2)10-8(4)7(3)9-5/h1-4H3
InChI keyFINHMKGKINIASC-UHFFFAOYSA-N

安全信息

象形图GHS07
警示用语:Warning
危险声明H302 - H315 - H319 - H335
预防措施声明P261 - P264 - P270 - P301 + P312 - P302 + P352 - P305 + P351 + P338
危险分类Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官Respiratory system
储存分类代码11 - Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
个人防护装备dust mask type N95 (US), Eyeshields, Gloves
95162Supelco2,3,5,6-Tetramethylpyrazineanalytical standard2715.47元/100 MG;   展开

产品说明

一般描述

2,3,5,6-四甲基吡嗪是一种吡嗪类风味化合物。它是用于治疗哮喘的中药川芎和麻黄的主要活性成分。

应用

2,3,5,6-四甲基吡嗪可用作分析参考标准品,用于通过不同的色谱技术对麻黄草麻黄中的分析物进行定量。
有关合适仪器技术的更多信息,请参考产品分析证书。如需进一步支持,请联系技术服务。

包装

无底玻璃瓶。内含物在插入的融合锥体内。

基本信息

经验(实验)分子式C8H12N2
分子量136.19
Beilstein113100
EC 号214-391-2
MDL编号MFCD00006146
PubChem化学物质编号329770426
NACRESNA.24

产品性质

质量水平100
等级analytical standard
测定≥98.0% (GC)
保质期limited shelf life, expiry date on the label
technique(s)HPLC: suitable
gas chromatography (GC): suitable
bp190 ℃ (lit.)
mp77-80 ℃ (lit.)
85-87 ℃
application(s)cleaning products
cosmetics
flavors and fragrances
food and beverages
personal care
格式neat
SMILES stringCc1nc(C)c(C)nc1C
InChI1S/C8H12N2/c1-5-6(2)10-8(4)7(3)9-5/h1-4H3
InChI keyFINHMKGKINIASC-UHFFFAOYSA-N

安全信息

象形图GHS07
警示用语:Warning
危险声明H302 - H315 - H319 - H335
预防措施声明P261 - P264 - P270 - P301 + P312 - P302 + P352 - P305 + P351 + P338
危险分类Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官Respiratory system
储存分类代码11 - Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
078918Fluorochem2,3,5,6-Tetramethylpyrazine95%220元/10g;   352元/25g;   924元/100g;   4488元/500g;   展开

基本信息

CAS Number1124-11-4
MDL NumberMFCD00006146
Boiling Point192.7 ℃ at 760 mmHg
Melting Point77-80℃

安全信息

图形或危害标志
危险性说明 H302: Harmful if swallowed.
H315: Causes skin irritation.
H318: Causes serious eye damage.
H335: May cause respiratory irritation.
防范说明 P233: Keep container tightly closed.
P260: Do not breathe .
P261: Avoid breathing
P264: Wash hands thoroughly after handling.
P270: Do not eat, drink or smoke when using this product.
P271: Use only outdoors or in a well-ventilated area.
P280: Wear .
P301 + P312: IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell.
P302 + P352: IF ON SKIN: Wash with plenty of soap and water.
P304: IF INHALED: .
P304 + P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P310: Immediately call a POISON CENTER or doctor/physician.
P312: Call a POISON CENTER or doctor/physician if you feel unwell.
P321: Specific treatment (see . on this label).
P330: Rinse mouth.
P332 + P313: If skin irritation occurs: Get medical advice/ attention.
P340: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P362: Take off contaminated clothing and wash before reuse.
P403: Store in a well-ventilated place.
P403 + P233: Store in a well-ventilated place. Keep container tightly closed.
P405: Store locked up.
P501: Dispose of contents/container to local regulations.
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