CAS 109552-15-0; 帕咪磷酸二钠; phosphonic acid, (3-amino-1-hydroxypropylidene)bis-, disodium salt, pentahydrat

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CAS:

109552-15-0

分子式:

C₃H₂₁NNa₂O₁₂P₂ ₂+

分子量:

371.12

中文名称:

帕咪磷酸二钠

英文名称:

phosphonic acid, (3-amino-1-hydroxypropylidene)bis-, disodium salt, pentahydrat

aredia

disodium (3-amino-1-hydroxypropylidene)bisphosphonate pentahydrate

disodium dihydrogen (3-amino-1-hydroxypropylidene)diphosphate pentahydrate

pamidronate

phosphonic acid, (3-amino-1-hydroxypropylidene)bis-,disodium salt, pentahydrate

用途:

帕米膦酸(Pamidronate)二钠五水合物是预防骨质疏松症的化合物。

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货号

品牌

产品名称

规格

包装、参考价格

详情

P884583

MACKLIN

Pamidronate disodium pentahydrate

≥98%

521元/10mg; 1996元/50mg;

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储存：2-8℃
状态：白色固体

Y0000524

Pamidronate disodium pentahydrate

European Pharmacopoeia (EP) Reference Standard

1559.78元/ ;

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产品说明

一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

包装

Unit quantity: 10 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

注意

Please find SDS provided by EDQM here..

其他说明

Sales restrictions may apply.

基本信息

经验(实验)分子式	C₃H₉NNa₂O₇P₂ · 5H₂O
分子量	369.11
NACRES	NA.24

产品性质

等级	pharmaceutical primary standard
manufacturer/tradename	EDQM
application(s)	pharmaceutical (small molecule)
格式	neat
储存温度	2-8℃
InChI	1S/C3H11NO7P2.2Na.5H2O/c4-2-1-3(5,12(6,7)8)13(9,10)11;;;;;;;/h5H,1-2,4H2,(H2,6,7,8)(H2,9,10,11);;;51H2/q;2+1;;;;;/p-2
InChI key	CZYWHNTUXNGDGR-UHFFFAOYSA-L

安全信息

象形图
警示用语：	Warning
危险声明	H302 - H319
预防措施声明	P301 + P312 + P330 - P305 + P351 + P338
危险分类	Acute Tox. 4 Oral - Eye Irrit. 2
储存分类代码	13 - Non Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable

1492801

USP

Pamidronate disodium

United States Pharmacopeia (USP) Reference Standard

4828.92元/100 MG;

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产品说明

一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

分析说明

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.

其他说明

USP issued SDS can be found here.
Sales restrictions may apply.

基本信息

经验(实验)分子式	C₃H₉NNa₂O₇P₂ · 5H₂O
分子量	369.11
NACRES	NA.24

产品性质

等级	pharmaceutical primary standard
manufacturer/tradename	USP
application(s)	pharmaceutical (small molecule)
格式	neat
储存温度	2-8℃
InChI	1S/C3H11NO7P2.2Na.5H2O/c4-2-1-3(5,12(6,7)8)13(9,10)11;;;;;;;/h5H,1-2,4H2,(H2,6,7,8)(H2,9,10,11);;;51H2/q;2+1;;;;;/p-2
InChI key	CZYWHNTUXNGDGR-UHFFFAOYSA-L

安全信息

象形图
警示用语：	Warning
危险声明	H302 - H319
预防措施声明	P264 - P270 - P280 - P301 + P312 - P305 + P351 + P338 - P337 + P313
危险分类	Acute Tox. 4 Oral - Eye Irrit. 2
储存分类代码	11 - Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable

506600

Sigma-Aldrich

Pamidronate, Disodium Salt-CAS 109552-15-0-Calbiochem

A potent and specific inhibitor of bone resorption that does not cause any significant detrimental effect on bone growth and mineralization at concentrations used.

1633.58元/10 MG;

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产品说明

一般描述

A potent and specific inhibitor of bone resorption that does not cause any significant detrimental effect on bone growth and mineralization at concentrations used. Effective in a variety of conditions characterized by pathologically enhanced bone turnover, including Paget’s disease, hypercalcaemia of malignancy, osteolytic bone metastasis, steroid-induced osteoporosis, and idiopathic osteoporosis. Inhibits breast cancer cell growth by inducing cell death in vitro. Provided in hydrated form, contains five molecules of water.
A calcium metabolism regulator. A potent and specific inhibitor of bone resorption at doses devoid of any significant detrimental effect on bone growth and mineralization. Effective in a variety of conditions characterized by pathologically enhanced bone turnover, including Paget′s disease, hypercalcemia of malignancy, osteolytic bone metastasis, and steroid-induced cell death in vitro. Provided in a hydrated form containing five molecules of water.

包装

10 mg in Plastic ampoule

生化/生理作用

Primary Target
Inhibitor of bone resorption
Product does not compete with ATP.
Reversible: no
Cell permeable: no

警告

Toxicity: Harmful & Carcinogenic / Teratogenic (E)

重悬

Following reconstitution, refrigerate (4°C). Stock solutions are stable for up to 6 months at 4°C.

其他说明

Fromigue, O., et al. 2000. J. Bone Miner. Res.15, 2211.
Fitton, A., and McTravish, D. 1991. Drugs41, 289.

法律信息

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

基本信息

经验(实验)分子式	C₃H₉NO₇P₂ · 2Na · 5H₂O
分子量	369.11

产品性质

质量水平	100
测定	≥98% (HPLC)
形式	solid
manufacturer/tradename	Calbiochem^®
储存条件	OK to freeze desiccated (hygroscopic)
颜色	white
溶解性	water: 10 mg/mL
运输	ambient
储存温度	−20℃
InChI	1S/C3H11NO7P2.2Na.5H2O/c4-2-1-3(5,12(6,7)8)13(9,10)11;;;;;;;/h5H,1-2,4H2,(H2,6,7,8)(H2,9,10,11);;;51H2/q;2+1;;;;;/p-2
InChI key	CZYWHNTUXNGDGR-UHFFFAOYSA-L

安全信息

象形图
警示用语：	Warning
危险声明	H302 - H319
预防措施声明	P264 - P270 - P280 - P301 + P312 - P305 + P351 + P338 - P337 + P313
危险分类	Acute Tox. 4 Oral - Eye Irrit. 2
储存分类代码	11 - Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable

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