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CAS: 109-00-2
分子式: C5H5NO
分子量: 95.10
沸点: 180℃(22
熔点: 123-130℃
中文名称: 
氮苯酮
3-吡啶酮
3-羟基吡啶
3-吡啶酚
英文名称: 
3-Hydroxypyridine
3-Pyridinol
3-pyridol
3-pyridyl alcohol
beta-hydroxypyridine
m-hydroxypyridine
Pyridin-3-ol
3(1H)-Pyridone
3-Pyridone
性质描述: 无色针状结晶。熔点129℃。溶于醇和水,微溶于醚和苯。遇三氯化铁成红色溶液,在空气中易分解。
生产方法: 由吡啶经磺化、碱熔、中和而得。将发烟硫酸加入干燥的反应锅内,搅拌下滴加吡啶,再加入硫酸汞。加热至230-240℃,保温13-14h。冷至20-25℃,加入乙醇中,继续冷至5℃以下,析出结晶。过滤,得吡啶-3-磺酸。熔点345℃,收率62%。将氢氧化钠及吡啶-3-磺酸加入反应锅内,在160℃熔融,升温至220-230℃保温4h。冷至100℃,加水溶解,用30%的盐酸调节pH至4,减压浓缩,过滤 除去氯化钠。滤液用饱和碳酸钠调节pH至8-9,冷却过滤,烘干,得3-羟基吡啶粗品,收率64%。用甲苯进行重结晶而得精品,熔点126-128℃,含量98%,精制收率80%。
用途: 用作医药中间体。
推荐供应商
货号品牌产品名称规格包装、参考价格详情
H810995MACKLIN3-羟基吡啶99%31元/25g;   55元/100g;   255元/500g;   1173元/2.5kg;   展开
储存:室温
状态:白色到浅黄色粉末
H0331TCI3-Hydroxypyridine>98.0%(GC)(T)230元/25G;   590元/100G;   1890元/500G;   展开

基本信息

纯度/分析方法>98.0%(GC)(T)
分子式/分子量C5H5NO = 95.10
外观与形状(20℃)固体
Reaxys-RN105699
PubChem物质ID87570749
SDBS (AIST Spectral DB)1083
MDL编号MFCD00006378

技术规格

AppearanceWhite to Brown powder to crystal
Purity(GC)min. 98.0 %
Purity(Nonaqueous Titration)min. 98.0 %
Melting point126.0 to 130.0 ℃

物性(参考值)

熔点126 ℃
沸点180 ℃/22 mmHg
水溶性可溶
在水中的溶解度33 g/l   20 ℃

安全信息

图形或危害标志
信号词警告
危险性说明H315 : 造成皮肤刺激。
H319 : 造成严重眼刺激。
防范说明P264 : 作业后彻底清洗皮肤。
P280 : 戴防护手套/戴防护眼罩/戴防护面具。
P302 + P352 : 如皮肤沾染:用水充分清洗。
P337 + P313 : 如仍觉眼刺激:求医/就诊。
P305 + P351 + P338 : 如进入眼睛:用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出,取出隐形眼镜。继续冲洗。
P362+P364 : 脱掉沾污的衣服,清洗后方可重新使用。
P332 + P313 : 如发生皮肤刺激:求医/就诊。

相关法规

RTECS#UU7701400
272460J&K3-Hydroxypyridine98%60元/5G;   77元/25G;   213元/100G;   展开

基本信息

分子式C5H5NO
分子量95.10
熔点125-128
MDL编码MFCD00006378
Beilstein105699
EINECS 编号203-637-4

安全信息

图形或危害标志
提示语Warning
危险说明H315
H319
H335
防范说明P261
P305+P351+P338
WGK3
RTECSUU7701400
TSCA
A13910Alfa Aesar3-Hydroxypyridine98%371元/50g;   700元/100g;   2361元/500g;   4154元/1000g;   展开

基本信息

MDL
MFCD00006378

EINECS
203-637-4

分子式
C5H5NO

分子量
95.10

熔点
125-128°

沸点
180°/22mm

闪点
173°(343°F)

灵敏度
Light Sensitive. Ambient temperatures.

形态
Powder

Beilstein
105699

GHS危害和防范说明

GHS符号

Hazard Statements
H315-H319-H335
Causes skin irritation.Causes serious eye irritation.May cause respiratory irritation.

Precautionary Statements
P261-P280a-P305+P351+P338-P304+P340-P405-P501a
Avoid breathing dust/fume/gas/mist/vapours/spray.Wear protective gloves and eye/face protection.IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing.Store locked up.Dispose of contents/container in accordance with local/regional/national/international regulations.

安全信息

危险等级
6.1

包装组
III

危险类别
36/37/38
Irritating to eyes, respiratory system and skin.

安全等级
26-37
In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.

RTECS
UU7701400

TSCA

C12185Alfa Aesar3-Hydroxypyridine98%1028元/100g;   4452元/500g;   展开

基本信息

Ref#
12185

MDL
6378

分子式
C5 H5 N O

分子量
95.1

形态
Pale cream to pale brown powder

安全信息

危险等级
6.1

包装组
III

H57009Sigma-Aldrich3-Hydroxypyridine98%336.5元/25 G;   406.16元/100 G;   1929.57元/500 G;   11707.2元/5 KG;   展开

基本信息

经验(实验)分子式C5H5NO
分子量95.10
Beilstein105699
EC 号203-637-4
MDL编号MFCD00006378
PubChem化学物质编号24895705
NACRESNA.22

产品性质

质量水平200
测定98%
mp125-128 ℃ (lit.)
SMILES stringOc1cccnc1
InChI1S/C5H5NO/c7-5-2-1-3-6-4-5/h1-4,7H
InChI keyGRFNBEZIAWKNCO-UHFFFAOYSA-N

安全信息

象形图GHS07
警示用语:Warning
危险声明H315 - H319 - H335
预防措施声明P302 + P352 - P305 + P351 + P338
危险分类Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官Respiratory system
储存分类代码11 - Combustible Solids
WGKWGK 3
个人防护装备dust mask type N95 (US), Eyeshields, Gloves
V900285Sigma-Aldrich3-HydroxypyridineVetec, reagent grade, 99%221.79元/25 G;   402.91元/100 G;   展开

产品说明

包装

25, 100 g in glass bottle

法律信息

Vetec is a trademark of sigma-aldrich International GmbH

基本信息

经验(实验)分子式C5H5NO
分子量95.10
Beilstein105699
EC 号203-637-4
MDL编号MFCD00006378
PubChem化学物质编号329829710

产品性质

等级reagent grade
产品线Vetec
测定99%
mp125-128 ℃ (lit.)
SMILES stringOc1cccnc1
InChI1S/C5H5NO/c7-5-2-1-3-6-4-5/h1-4,7H
InChI keyGRFNBEZIAWKNCO-UHFFFAOYSA-N

安全信息

象形图GHS07
警示用语:Warning
危险声明H315 - H319 - H335
预防措施声明P261 - P305 + P351 + P338
危险分类Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
储存分类代码13 - Non Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
045225Fluorochem3-Hydroxypyridine98%220元/1g;   264元/25g;   682元/100g;   2728元/500g;   展开

基本信息

CAS Number109-00-2
MDL NumberMFCD00006378
Boiling Point280-281℃
Melting Point123-130℃
Density1.1418

安全信息

图形或危害标志
危险性说明 H315: Causes skin irritation.
H319: Causes serious eye irritation.
H335: May cause respiratory irritation.
防范说明 P233: Keep container tightly closed.
P260: Do not breathe .
P261: Avoid breathing .
P264: Wash hands thoroughly after handling.
P271: Use only outdoors or in a well-ventilated area.
P280: Wear .
P302 + P352: IF ON SKIN: Wash with plenty of soap and water.
P304: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing..
P304 + P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P312: Call a POISON CENTER or doctor/physician if you feel unwell.
P321: Specific treatment (see relevant procedures. on this label).
P332 + P313: If skin irritation occurs: Get medical advice/ attention.
P337 + P313: If eye irritation persists: Get medical advice/attention.
P340: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P362: Take off contaminated clothing and wash before reuse.
P403: Store in a well-ventilated place.
P403 + P233: Store in a well-ventilated place. Keep container tightly closed.
P405: Store locked up.
P501: Dispose of contents/container to in accordance with local regulation .
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