| 货号 | 品牌 | 产品名称 | 规格 | 包装、参考价格 | |
| D819096 | MACKLIN | DL-硫辛酸 | 99% | 30元/5g; 59元/25g; 169元/100g; 699元/500g; 3396元/2.5kg; | 咨询 |
储存：-20℃, 避光, 惰性气体保存 状态：黄色粉末、晶体和/或块状物 |
| D796082 | MACKLIN | DL-硫辛酸 | 10mM in DMSO | 186元/1ml; | 咨询 |
储存：-20℃, 避光, 惰性气体保存 状态：黄色粉末、晶体和/或块状物 |
| L0058 | TCI | DL-α-Lipoic Acid | >99.0%(T) | 845元/5G; 2500元/25G; | 咨询 |
基本信息 | 纯度/分析方法 | >99.0%(T) | | 分子式/分子量 | C8H14O2S2 = 206.32 | | 外观与形状(20℃) | 固体 | | 储存温度 | 0-10℃ | | 储存在惰性气体下 | 存放于惰性气体之中 | | 应避免的情况 | 光,空气,湿气 (吸湿),加热 | | Reaxys-RN | 81851 | | PubChem物质ID | 87572024 | | SDBS (AIST Spectral DB) | 10401 | | Merck Index (14) | 9326 | | MDL编号 | MFCD00005474 |
技术规格 | Appearance | Light orange to Yellow to Green powder to crystal | | Purity(HPLC) | min. 98.0 area% | | Purity(Neutralization titration) | min. 99.0 % |
物性(参考值) | 沸点 | 165 ℃ | | 水溶性 | 不溶 | | 溶解性(可溶于) | 甲苯,乙醇 |
安全信息 | 图形或危害标志 |  | | 信号词 | 警告 | | 危险性说明 | H302 : 吞咽有害。
H315 : 造成皮肤刺激。
H319 : 造成严重眼刺激。
| | 防范说明 | P501 : 将内装物/容器送到批准的废物处理厂处理。
P270 : 使用本产品时不要进食、饮水或吸烟。
P264 : 作业后彻底清洗皮肤。
P280 : 戴防护手套/戴防护眼罩/戴防护面具。
P302 + P352 : 如皮肤沾染：用水充分清洗。
P337 + P313 : 如仍觉眼刺激：求医/就诊。
P305 + P351 + P338 : 如进入眼睛：用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出，取出隐形眼镜。继续冲洗。
P362+P364 : 脱掉沾污的衣服，清洗后方可重新使用。
P332 + P313 : 如发生皮肤刺激：求医/就诊。
P301 + P312 + P330 : 如误吞咽：如感觉不适，呼叫急救中心/医生。漱口。
|
相关法规 |
| 203615 | J&K | Thioctic acid | 98% | 60元/5G; 178元/25G; | 咨询 |
基本信息 | 分子式 | C8H14O2S2 | | 分子量 | 206.33 | | 熔点 | 60-63 | | 沸点 | 160-165 | | MDL编码 | MFCD00005474 | | Beilstein | 81853 | | Merck | 14,9326 | | EINECS 编号 | 214-071-2 | | 存储条件 | Store at 2-8℃ |
安全信息 | 图形或危害标志 | | | 提示语 | Warning | | 危险说明 | H302 | | 防范说明 | P261
P280
P301+P312
P302+P352
P305+P351+P338 | | WGK | 3 | | RTECS | JP1192000 |
|
| 990002 | J&K | Thioctic acid | 98%, 干燥失重:≤0.2% | 409元/5G; 1629元/25G; | 咨询 |
基本信息 | 分子式 | C8H14O2S2 | | 分子量 | 206.33 | | 熔点 | 60-63 | | 沸点 | 160-165 | | MDL编码 | MFCD00005474 | | Beilstein | 81853 | | Merck | 14,9326 | | EINECS 编号 | 214-071-2 | | 存储条件 | Store at 2-8℃ |
安全信息 | 图形或危害标志 | | | 提示语 | Warning | | 危险说明 | H302 | | 防范说明 | P261
P280
P301+P312
P302+P352
P305+P351+P338 | | WGK | 3 | | RTECS | JP1192000 |
|
| L04711 | Alfa Aesar | DL-Thioctic Acid | 98% | 705元/5g; 2585元/25g; | 咨询 |
应用
DL-Thioctic acid is used as a major nutrient supplement. It is also reported as an antioxidant and used as a drug against diabetes. It plays an essential role in aerobic metabolism. Further, it acts as a free radical scavenger. 备注
Incompatible with strong oxidizing agents. 基本信息 MDL
MFCD00005474 EINECS
214-071-2 分子式
C8H14O2S2 分子量
206.33 熔点
59-63° 沸点
160-165° 灵敏度
Keep Cold. 形态
Crystalline powder 溶解性
Soluble in methanol, ethanol, diethyl ether and chloroform. Insoluble in water. Beilstein
81853 Merck
14,9326 GHS危害和防范说明 GHS符号
Hazard Statements
H302-H315-H319-H335
Harmful if swallowed.Causes skin irritation.Causes serious eye irritation.May cause respiratory irritation. Precautionary Statements
P261-P280a-P305+P351+P338-P304+P340-P405-P501a
Avoid breathing dust/fume/gas/mist/vapours/spray.Wear protective gloves and eye/face protection.IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing.Store locked up.Dispose of contents/container in accordance with local/regional/national/international regulations. 安全信息 危险类别
22-36/37/38
Harmful if swallowed.Irritating to eyes, respiratory system and skin. 安全等级
26-36/37-60
In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.Wear suitable protective clothing and gloves.This material and its container must be disposed of as hazardous waste 欧盟危险品标志
 RTECS
JP1192000 TSCA
否 |
| J18505 | Alfa Aesar | DL-alpha-Lipoic acid | 98+% (dry basis), Thermo Scientific | 2579元/25g; 4324元/50g; 8647元/100g; | 咨询 |
基本信息 MDL
MFCD00005474 EINECS
214-071-2 分子量
206.33 熔点
59-63° 沸点
160-165° 灵敏度
Ambient temperatures. 形态
Crystalline powder Beilstein
81853 Merck
14,9326 安全信息 危险类别
22-36/37/38
Harmful if swallowed.Irritating to eyes, respiratory system and skin. 安全等级
26-36/37-60
In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.Wear suitable protective clothing and gloves.This material and its container must be disposed of as hazardous waste RTECS
JP1192000 TSCA
否 |
| Y0000546 | | Thioctic acid | European Pharmacopoeia (EP) Reference Standard | 1572.27元/ ; | 咨询 |
产品说明 一般描述 This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia. 生化/生理作用 维持酶复合物(例如丙酮酸脱氢酶和甘氨酸脱羧酶的复合物)活性所需的抗氧化剂和辅酶。通过两种或多种酶的作用在细胞内还原外源性硫辛酸。然后，该还原形式通过直接清除自由基、循环利用其他抗氧化剂、增加谷胱甘肽的合成以及调控转录因子(尤其是 NF-κB)的活性而影响许多细胞过程。减少巨噬细胞对髓磷脂的吞噬。 包装 Unit quantity: 110 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue. 注意 Please find SDS provided by EDQM here.. 其他说明 Sales restrictions may apply. 基本信息 | 经验(实验)分子式 | C8H14O2S2 | | 分子量 | 206.33 | | Beilstein | 81853 | | MDL编号 | MFCD00005474 | | PubChem化学物质编号 | 329831010 | | NACRES | NA.24 |
产品性质 | 等级 | pharmaceutical primary standard | | manufacturer/tradename | EDQM | | application(s) | pharmaceutical (small molecule) | | 格式 | neat | | 储存温度 | 2-8℃ | | SMILES string | OC(=O)CCCCC1CCSS1 | | InChI | 1S/C8H14O2S2/c9-8(10)4-2-1-3-7-5-6-11-12-7/h7H,1-6H2,(H,9,10) | | InChI key | AGBQKNBQESQNJD-UHFFFAOYSA-N |
安全信息 | 象形图 |  | | 警示用语： | Warning | | 危险声明 | H302 - H315 - H317 - H319 - H411 | | 预防措施声明 | P273 - P280 - P301 + P312 + P330 - P302 + P352 - P305 + P351 + P338 | | 危险分类 | Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1 | | 储存分类代码 | 11 - Combustible Solids | | WGK | WGK 2 | | 闪点(F) | Not applicable | | 闪点(C) | Not applicable |
|
| Y0000545 | | Thioctic acid containing impurity B | European Pharmacopoeia (EP) Reference Standard | 1572.27元/ ; | 咨询 |
产品说明 一般描述 This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia. 生化/生理作用 维持酶复合物(例如丙酮酸脱氢酶和甘氨酸脱羧酶的复合物)活性所需的抗氧化剂和辅酶。通过两种或多种酶的作用在细胞内还原外源性硫辛酸。然后，该还原形式通过直接清除自由基、循环利用其他抗氧化剂、增加谷胱甘肽的合成以及调控转录因子(尤其是 NF-κB)的活性而影响许多细胞过程。减少巨噬细胞对髓磷脂的吞噬。 包装 Unit quantity: 25 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue. 注意 Please find SDS provided by EDQM here.. 其他说明 Sales restrictions may apply. 基本信息 | 经验(实验)分子式 | C8H14O2S2 | | 分子量 | 206.33 | | Beilstein | 81853 | | MDL编号 | MFCD00005474 | | PubChem化学物质编号 | 329831009 | | NACRES | NA.24 |
产品性质 | 等级 | pharmaceutical primary standard | | manufacturer/tradename | EDQM | | application(s) | pharmaceutical (small molecule) | | 格式 | neat | | 储存温度 | 2-8℃ | | SMILES string | OC(=O)CCCCC1CCSS1 | | InChI | 1S/C8H14O2S2/c9-8(10)4-2-1-3-7-5-6-11-12-7/h7H,1-6H2,(H,9,10) | | InChI key | AGBQKNBQESQNJD-UHFFFAOYSA-N |
安全信息 | 象形图 | | | 警示用语： | Warning | | 危险声明 | H302 - H315 - H317 - H319 - H411 | | 预防措施声明 | P273 - P280 - P301 + P312 + P330 - P302 + P352 - P305 + P351 + P338 | | 危险分类 | Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1 | | 储存分类代码 | 11 - Combustible Solids | | WGK | WGK 2 | | 闪点(F) | Not applicable | | 闪点(C) | Not applicable |
|
| Y0000592 | | Thioctic acid for system suitability | European Pharmacopoeia (EP) Reference Standard | 1572.27元/ ; | 咨询 |
产品说明 一般描述 This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia. 生化/生理作用 维持酶复合物(例如丙酮酸脱氢酶和甘氨酸脱羧酶的复合物)活性所需的抗氧化剂和辅酶。通过两种或多种酶的作用在细胞内还原外源性硫辛酸。然后，该还原形式通过直接清除自由基、循环利用其他抗氧化剂、增加谷胱甘肽的合成以及调控转录因子(尤其是 NF-κB)的活性而影响许多细胞过程。减少巨噬细胞对髓磷脂的吞噬。 包装 Unit quantity: 15 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue. 注意 Please find SDS provided by EDQM here.. 其他说明 Sales restrictions may apply. 基本信息 | 经验(实验)分子式 | C8H14O2S2 | | 分子量 | 206.33 | | Beilstein | 81853 | | MDL编号 | MFCD00005474 | | PubChem化学物质编号 | 329831039 | | NACRES | NA.24 |
产品性质 | 等级 | pharmaceutical primary standard | | manufacturer/tradename | EDQM | | application(s) | pharmaceutical (small molecule) | | 格式 | neat | | 储存温度 | 2-8℃ | | SMILES string | OC(=O)CCCCC1CCSS1 | | InChI | 1S/C8H14O2S2/c9-8(10)4-2-1-3-7-5-6-11-12-7/h7H,1-6H2,(H,9,10) | | InChI key | AGBQKNBQESQNJD-UHFFFAOYSA-N |
安全信息 | 象形图 | | | 警示用语： | Warning | | 危险声明 | H302 - H315 - H317 - H319 - H411 | | 预防措施声明 | P273 - P280 - P301 + P312 + P330 - P302 + P352 - P305 + P351 + P338 | | 危险分类 | Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1 | | 储存分类代码 | 11 - Combustible Solids | | WGK | WGK 2 | | 闪点(F) | Not applicable | | 闪点(C) | Not applicable |
|
| T1395 | Sigma-Aldrich | (±)-α-Lipoic acid | BioReagent, suitable for cell culture, ≥99% | 706.59元/1 G; 1598.19元/5 G; | 咨询 |
产品说明 一般描述 α-硫辛酸(LA)是蔬菜和肉类中的营养成分，同时具有抗氧化和氧化特性。α-硫辛酸对许多疾病(如肝硬化，重金属中毒和糖尿病多发性神经病变)具有治疗潜力。α-硫辛酸通过氧化应激相关途径或通过激活半胱天冬酶在癌细胞中发挥凋亡潜能。α-硫辛酸改善线粒体功能，并在线粒体能量代谢中起关键作用。 应用 硫辛酸已被用于： - 诱导红细胞衰亡
- 作为神经元培养的 NS21 培养基的一种成分
- 通过高效液相色谱法(HPLC)评估其对肝脏能量代谢的影响，以及在脂多糖(LPS)预处理小鼠中，通过线粒体基因表达研究来评估线粒体功能
- 说明其对肺部百草枯中毒的影响
包装 1, 5 g in poly bottle 生化/生理作用 维持酶复合物(例如丙酮酸脱氢酶和甘氨酸脱羧酶的复合物)活性所需的抗氧化剂和辅酶。通过两种或多种酶的作用在细胞内还原外源性硫辛酸。然后，该还原形式通过直接清除自由基、循环利用其他抗氧化剂、增加谷胱甘肽的合成以及调控转录因子(尤其是 NF-κB)的活性而影响许多细胞过程。减少巨噬细胞对髓磷脂的吞噬。 其他说明 氧化形式 基本信息 | 经验(实验)分子式 | C8H14O2S2 | | 分子量 | 206.33 | | Beilstein | 81853 | | EC 号 | 214-071-2 | | MDL编号 | MFCD00005474 | | PubChem化学物质编号 | 24899963 | | NACRES | NA.71 |
产品性质 | 质量水平 | 200 | | 产品线 | BioReagent | | 测定 | ≥99% | | technique(s) | cell culture | mammalian: suitable | | 溶解性 | ethanol: 50 mg/mL | | SMILES string | OC(=O)CCCCC1CCSS1 | | InChI | 1S/C8H14O2S2/c9-8(10)4-2-1-3-7-5-6-11-12-7/h7H,1-6H2,(H,9,10) | | InChI key | AGBQKNBQESQNJD-UHFFFAOYSA-N | | Gene Information | human ... ACHE(43), BCHE(590)
rat ... Adra1a(29412), Adra1b(24173), Adra1d(29413) |
安全信息 | 象形图 | | | 警示用语： | Warning | | 危险声明 | H302 - H315 - H317 - H319 - H411 | | 预防措施声明 | P261 - P273 - P280 - P301 + P312 - P302 + P352 - P305 + P351 + P338 | | 危险分类 | Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1 | | 储存分类代码 | 11 - Combustible Solids | | WGK | WGK 2 | | 闪点(F) | Not applicable | | 闪点(C) | Not applicable | | 个人防护装备 | dust mask type N95 (US), Eyeshields, Gloves |
|
| T5625 | Sigma-Aldrich | (±)-α-Lipoic acid | synthetic, ≥99% (titration), powder | 292.55元/500 MG; 498.71元/1 G; 1180.59元/5 G; 4757.54元/25 G; 8140.61元/50 G; | 咨询 |
产品说明 应用 α-LA可以恢复高脂肪喂养的糖尿病大鼠的内皮活动，并减轻氧化应激4。它还用于分析星形胶质细胞中的ROS 产生5。 包装 500 mg in poly bottle
1, 5, 25, 50 g in poly bottle 生化/生理作用 维持酶复合物(例如丙酮酸脱氢酶和甘氨酸脱羧酶的复合物)活性所需的抗氧化剂和辅酶。通过两种或多种酶的作用在细胞内还原外源性硫辛酸。然后，该还原形式通过直接清除自由基、循环利用其他抗氧化剂、增加谷胱甘肽的合成以及调控转录因子(尤其是 NF-κB)的活性而影响许多细胞过程。减少巨噬细胞对髓磷脂的吞噬。 制备说明 (±)-α-硫辛酸(α-LA)以 50mg/ml的浓度溶于乙醇 基本信息 | 经验(实验)分子式 | C8H14O2S2 | | 分子量 | 206.33 | | Beilstein | 81853 | | EC 号 | 214-071-2 | | MDL编号 | MFCD00005474 | | PubChem化学物质编号 | 57654679 | | NACRES | NA.77 |
产品性质 | 质量水平 | 200 | | 生物来源 | synthetic | | 描述 | Oxidized form | | 测定 | ≥99% (titration) | | 形式 | powder | | 溶解性 | ethanol: soluble 50 mg/mL | | SMILES string | OC(=O)CCCCC1CCSS1 | | InChI | 1S/C8H14O2S2/c9-8(10)4-2-1-3-7-5-6-11-12-7/h7H,1-6H2,(H,9,10) | | InChI key | AGBQKNBQESQNJD-UHFFFAOYSA-N | | Gene Information | human ... ACHE(43), BCHE(590)
rat ... Adra1a(29412), Adra1b(24173), Adra1d(29413) |
安全信息 | 象形图 | | | 警示用语： | Warning | | 危险声明 | H302 - H315 - H317 - H319 - H411 | | 预防措施声明 | P261 - P273 - P280 - P301 + P312 - P302 + P352 - P305 + P351 + P338 | | 危险分类 | Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1 | | 储存分类代码 | 11 - Combustible Solids | | WGK | WGK 2 | | 闪点(F) | Not applicable | | 闪点(C) | Not applicable | | 个人防护装备 | dust mask type N95 (US), Eyeshields, Gloves |
|
| 1368201 | USP | Alpha Lipoic Acid | United States Pharmacopeia (USP) Reference Standard | 2914.43元/500 MG; | 咨询 |
产品说明 一般描述 本产品按照现行药典要求提供和指定。所有为支持本产品而提供的信息，包括 SDS 和任何产品信息小册子，均由药典颁发机构制定和发布。如需进一步的信息和支持，请访问现行药典网站。如需进一步信息和支持，请访问现行药典网站。 生化/生理作用 维持酶复合物(例如丙酮酸脱氢酶和甘氨酸脱羧酶的复合物)活性所需的抗氧化剂和辅酶。通过两种或多种酶的作用在细胞内还原外源性硫辛酸。然后，该还原形式通过直接清除自由基、循环利用其他抗氧化剂、增加谷胱甘肽的合成以及调控转录因子(尤其是 NF-κB)的活性而影响许多细胞过程。减少巨噬细胞对髓磷脂的吞噬。 分析说明 这些产品仅供测试和分析使用。它们不适用于人类或动物的给药，不可用于诊断、治疗或治愈任何疾病。 其他说明 USP颁布的SDS请点击此处。
可能适用相应的销售限制。 基本信息 | 经验(实验)分子式 | C8H14O2S2 | | 分子量 | 206.33 | | Beilstein | 81853 | | MDL编号 | MFCD00005474 | | PubChem化学物质编号 | 329750249 | | NACRES | NA.24 |
产品性质 | 等级 | pharmaceutical primary standard | | manufacturer/tradename | USP | | application(s) | pharmaceutical (small molecule) | | 格式 | neat | | 储存温度 | 2-8℃ | | SMILES string | OC(=O)CCCCC1CCSS1 | | InChI | 1S/C8H14O2S2/c9-8(10)4-2-1-3-7-5-6-11-12-7/h7H,1-6H2,(H,9,10) | | InChI key | AGBQKNBQESQNJD-UHFFFAOYSA-N |
安全信息 | 象形图 | | | 警示用语： | Warning | | 危险声明 | H302 - H315 - H317 - H319 - H411 | | 预防措施声明 | P273 - P280 - P301 + P312 + P330 - P302 + P352 - P305 + P351 + P338 | | 危险分类 | Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1 | | 储存分类代码 | 11 - Combustible Solids | | WGK | WGK 2 | | 闪点(F) | Not applicable | | 闪点(C) | Not applicable |
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| 437692 | Sigma-Aldrich | α-Lipoic Acid-CAS 1077-28-7-Calbiochem | α-Lipoic Acid, CAS 1077-28-7 is an oxidized form with antioxidant properties. Reduces renal lipid peroxidation in rats with cisplatin n-induced nephrotoxicity. | 1375.15元/5 G; | 咨询 |
产品说明 一般描述 Oxidized form. Has antioxidant properties. Growth factor for many bacteria and protozoa.
Oxidized form. Has antioxidant properties. Reported to effectively reduce renal lipid peroxidation in rats with cisplatin-induced nephrotoxicity. Acts as a growth factor for many bacteria and protozoa. 包装 5 g in Plastic ampoule 生化/生理作用 Primary Target
Reduce renal lipid peroxidation in rats with cisplatin-induced nephrotoxicity
Product does not compete with ATP.
Reversible: no
Cell permeable: no 警告 Toxicity: Harmful (C) 其他说明 Somami, S. M., et al. 2000. Pharmacol. Toxicol. 86, 234. 法律信息 CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany 基本信息 | 经验(实验)分子式 | C8H14O2S2 | | 分子量 | 206.33 | | MDL编号 | MFCD00005474 |
产品性质 | 质量水平 | 100 | | 测定 | ≥99% (by assay) | | 形式 | solid | | manufacturer/tradename | Calbiochem® | | 储存条件 | OK to freeze | | 颜色 | pale yellow | | 溶解性 | ethanol: soluble
methanol: soluble | | 运输 | ambient | | 储存温度 | 10-30℃ | | InChI | 1S/C8H14O2S2/c9-8(10)4-2-1-3-7-5-6-11-12-7/h7H,1-6H2,(H,9,10) | | InChI key | AGBQKNBQESQNJD-UHFFFAOYSA-N |
安全信息 | 象形图 | | | 警示用语： | Warning | | 危险声明 | H302 - H315 - H317 - H319 - H411 | | 预防措施声明 | P261 - P273 - P280 - P301 + P312 - P302 + P352 - P305 + P351 + P338 | | 危险分类 | Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1 | | 储存分类代码 | 11 - Combustible Solids | | WGK | WGK 2 | | 闪点(F) | Not applicable | | 闪点(C) | Not applicable |
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| 62320 | Sigma-Aldrich | (±)-α-Lipoic acid | ≥98.0% | 1101.87元/5 G; 2914.22元/25 G; | 咨询 |
产品说明 应用 (±)-α-硫辛酸已用于体外脂化研究和丙酮酸脱氢酶复合体(PDC)-丙酮酸脱氢酶激酶(PDHK)活性分析。它用于研究其对于产后砷暴露大鼠小脑发育的影响。 包装 5, 25 g in glass bottle 生化/生理作用 维持酶复合物(例如丙酮酸脱氢酶和甘氨酸脱羧酶的复合物)活性所需的抗氧化剂和辅酶。通过两种或多种酶的作用在细胞内还原外源性硫辛酸。然后，该还原形式通过直接清除自由基、循环利用其他抗氧化剂、增加谷胱甘肽的合成以及调控转录因子(尤其是 NF-κB)的活性而影响许多细胞过程。减少巨噬细胞对髓磷脂的吞噬。
(±)-α-硫辛酸可直接清除自由基，并能使升高的氧化应激水平下降。此外它还具有助氧化剂活性。αα-硫辛酸可在线粒体α酮酸脱氢酶复合体中发挥重要的辅基作用。它可用作糖尿病远端对称性多发性神经病变的潜力治疗药物。α-硫辛酸还用于治疗能量代谢损伤和氧化还原失衡疾病。 其他说明 综述 基本信息 | 经验(实验)分子式 | C8H14O2S2 | | 分子量 | 206.33 | | Beilstein | 81853 | | EC 号 | 214-071-2 | | MDL编号 | MFCD00005474 | | PubChem化学物质编号 | 57651855 | | NACRES | NA.21 |
产品性质 | 质量水平 | 200 | | 测定 | ≥98.0% (HPLC)
≥98.0% | | 灼烧残渣 | ≤0.1% | | 缺失 | ≤0.2% loss on drying | | mp | 60-62 ℃ | | 储存温度 | 2-8℃ | | SMILES string | OC(=O)CCCCC1CCSS1 | | InChI | 1S/C8H14O2S2/c9-8(10)4-2-1-3-7-5-6-11-12-7/h7H,1-6H2,(H,9,10) | | InChI key | AGBQKNBQESQNJD-UHFFFAOYSA-N | | Gene Information | human ... ACHE(43), BCHE(590)
rat ... Adra1a(29412), Adra1b(24173), Adra1d(29413) |
安全信息 | 象形图 | | | 警示用语： | Warning | | 危险声明 | H302 - H315 - H317 - H319 - H411 | | 预防措施声明 | P261 - P273 - P280 - P301 + P312 - P302 + P352 - P305 + P351 + P338 | | 危险分类 | Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1 | | 储存分类代码 | 11 - Combustible Solids | | WGK | WGK 2 | | 闪点(F) | Not applicable | | 闪点(C) | Not applicable | | 个人防护装备 | dust mask type N95 (US), Eyeshields, Gloves |
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| PHR2561 | Supelco | Alpha Lipoic Acid | | 1987.23元/1 g; | 咨询 |
产品说明 一般描述 Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards 生化/生理作用 维持酶复合物(例如丙酮酸脱氢酶和甘氨酸脱羧酶的复合物)活性所需的抗氧化剂和辅酶。通过两种或多种酶的作用在细胞内还原外源性硫辛酸。然后，该还原形式通过直接清除自由基、循环利用其他抗氧化剂、增加谷胱甘肽的合成以及调控转录因子(尤其是 NF-κB)的活性而影响许多细胞过程。减少巨噬细胞对髓磷脂的吞噬。 分析说明 These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available. 其他说明 This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis. 附注 To see an example of a Certificate of Analysis for this material enter LRAC6145 in the Documents slot below. This is an example certificate only and may not be the lot that you receive. 基本信息 | 经验(实验)分子式 | C8H14O2S2 | | 分子量 | 206.33 | | Beilstein | 81853 | | MDL编号 | MFCD00005474 |
产品性质 | 等级 | certified reference material
pharmaceutical secondary standard | | 描述 | Pharmaceutical Secondary Standard; Certified Reference Material | | 形式 | powder | | CofA | current certificate can be downloaded | | 包装 | pkg of 1 g | | 药典可追溯性 | traceable to PhEur Y0000546
traceable to USP 1368201 | | 储存温度 | 2-8℃ | | SMILES string | OC(=O)CCCCC1CCSS1 | | InChI | 1S/C8H14O2S2/c9-8(10)4-2-1-3-7-5-6-11-12-7/h7H,1-6H2,(H,9,10) | | InChI key | AGBQKNBQESQNJD-UHFFFAOYSA-N |
安全信息 | 象形图 | | | 警示用语： | Warning | | 危险声明 | H302 - H315 - H317 - H319 - H411 | | 预防措施声明 | P273 - P280 - P301 + P312 + P330 - P302 + P352 - P305 + P351 + P338 | | 危险分类 | Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1 | | 储存分类代码 | 13 - Non Combustible Solids | | WGK | WGK 2 | | 闪点(F) | Not applicable | | 闪点(C) | Not applicable |
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| 079457 | Fluorochem | 5-(1,2-Dithiolan-3-yl)pentanoic acid | 95% | 220元/1g; 440元/25g; 1166元/100g; | 咨询 |
基本信息 | CAS Number | 1077-28-7 | | MDL Number | MFCD00005474 |
安全信息 | 图形或危害标志 | | | 危险性说明 | H302: Harmful if swallowed.
H315: Causes skin irritation.
H319: Causes serious eye irritation.
H332: Harmful if inhaled.
H335: May cause respiratory irritation.
| | 防范说明 | P233: Keep container tightly closed.
P260: Do not breathe .
P261: Avoid breathing .
P264: Wash hands thoroughly after handling.
P270: Do not eat, drink or smoke when using this product.
P271: Use only outdoors or in a well-ventilated area.
P280: Wear .
P301 + P312: IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell.
P302 + P352: IF ON SKIN: Wash with plenty of soap and water.
P304: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing..
P304 + P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P312: Call a POISON CENTER or doctor/physician if you feel unwell.
P321: Specific treatment (see relevant procedures. on this label).
P330: Rinse mouth.
P332 + P313: If skin irritation occurs: Get medical advice/ attention.
P337 + P313: If eye irritation persists: Get medical advice/attention.
P340: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P362: Take off contaminated clothing and wash before reuse.
P403: Store in a well-ventilated place.
P403 + P233: Store in a well-ventilated place. Keep container tightly closed.
P405: Store locked up.
P501: Dispose of contents/container to in accordance with local regulation .
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