[登录] [免费注册]
试剂仪器网
发布求购
位置：首页 > 资料中心 > 化工字典 > 1071-46-1
关键词:       仅模糊查询
CAS: 1071-46-1
分子式: C5H8O4
分子量: 132.12
沸点: 106.5℃(3
中文名称: 
丙二酸单乙酯
英文名称: 
ethyl hydrogen malonate
Monoethyl malonate
用途: 医药中间体。
推荐供应商
货号品牌产品名称规格包装、参考价格详情
M797794MACKLIN丙二酸单乙酯10mM in DMSO185元/1ml;   展开
储存：-20°C, 密封, 干燥
M835536MACKLIN丙二酸单乙酯95%28元/1g;   32元/5g;   48元/25g;   187元/100g;   934元/500g;   展开
储存：室温,密封,干燥
状态：无色到黄色到红棕色液体
M2700TCIMonoethyl Malonate>98.0%(T)150元/5G;   550元/25G;   展开

基本信息

纯度/分析方法>98.0%(T)
分子式/分子量C5H8O4 = 132.12
外观与形状(20℃)液体
储存温度0-10℃
储存在惰性气体下存放于惰性气体之中
应避免的情况湿气 (分解),加热
Reaxys-RN1758845
PubChem物质ID253660441
MDL编号MFCD00020490

技术规格

AppearanceColorless to Light orange to Yellow clear liquid
Purity(Neutralization titration)min. 98.0 %

物性(参考值)

熔点-13 ℃
沸点208 ℃
比重1.19
折射率1.43

安全信息

图形或危害标志
信号词警告
危险性说明H315 : 造成皮肤刺激。
H319 : 造成严重眼刺激。
防范说明P264 : 作业后彻底清洗皮肤。
P280 : 戴防护手套/戴防护眼罩/戴防护面具。
P302 + P352 : 如皮肤沾染：用水充分清洗。
P337 + P313 : 如仍觉眼刺激：求医/就诊。
P305 + P351 + P338 : 如进入眼睛：用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出，取出隐形眼镜。继续冲洗。
P362+P364 : 脱掉沾污的衣服，清洗后方可重新使用。
P332 + P313 : 如发生皮肤刺激：求医/就诊。
044692Alfa AesarEthyl hydrogen malonate90+%635元/5g;   2607元/25g;   7963元/100g;   33448元/500g;   展开

应用
Ethyl hydrogen malonate is used as a reactant for the preparation of tetramic acids through Dieckmann ring closure and organocatalytic decarboxylative Doebner-Knoevenagel reactions. It is involved in the acylation reactions and Knoevenagel condensation with aldehydes. It is also used in the preparation of gamma-lactones from olefins by intermolecular carbolactonization in presence of Mn(III) acetate as a catalyst.

备注
Incompatible with strong oxidizing agents.

基本信息

MDL
MFCD00020490

EINECS
213-992-7

分子式
C5H8O4

分子量
132.12

沸点
106°/3mm

闪点
>110°(230°F)

密度
1.119

折射率
1.4295

灵敏度
Ambient temperatures.

形态
Liquid

溶解性
Miscible with water, chloroform and other solvents.

Beilstein
1758845

GHS危害和防范说明

GHS符号

Hazard Statements
H315-H319-H335
Causes skin irritation.Causes serious eye irritation.May cause respiratory irritation.

Precautionary Statements
P261-P280a-P305+P351+P338-P304+P340-P405-P501a
Avoid breathing dust/fume/gas/mist/vapours/spray.Wear protective gloves and eye/face protection.IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing.Store locked up.Dispose of contents/container in accordance with local/regional/national/international regulations.

安全信息

危险类别
36/37/38
Irritating to eyes, respiratory system and skin.

安全等级
23-26-37-60
Do not breathe gas/fumes/vapour/spray (appropriate wording to be specified by the manufacturer).In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.This material and its container must be disposed of as hazardous waste

TSCA
否

A12627Alfa AesarEthyl hydrogen malonate96%831元/10g;   3514元/50g;   8924元/250g;   展开

应用
Ethyl hydrogen malonate is used as a reactant for the preparation of tetramic acids through Dieckmann ring closure and organocatalytic decarboxylative Doebner-Knoevenagel reactions. It is involved in the acylation reactions and Knoevenagel condensation with aldehydes. It is also used in the preparation of gamma-lactones from olefins by intermolecular carbolactonization in presence of Mn(III) acetate as a catalyst.

备注
Incompatible with strong oxidizing agents.

基本信息

MDL
MFCD00020490

EINECS
213-992-7

分子式
C5H8O4

分子量
132.12

沸点
106°/3mm

闪点
>110°(230°F)

密度
1.119

折射率
1.4295

灵敏度
Keep Cold.

形态
Liquid

溶解性
Miscible with water, chloroform and other solvents.

Beilstein
1758845

GHS危害和防范说明

GHS符号

Hazard Statements
H315-H319-H335
Causes skin irritation.Causes serious eye irritation.May cause respiratory irritation.

Precautionary Statements
P261-P280a-P305+P351+P338-P304+P340-P405-P501a
Avoid breathing dust/fume/gas/mist/vapours/spray.Wear protective gloves and eye/face protection.IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing.Store locked up.Dispose of contents/container in accordance with local/regional/national/international regulations.

安全信息

危险类别
36/37/38
Irritating to eyes, respiratory system and skin.

安全等级
23-26-37-60
Do not breathe gas/fumes/vapour/spray (appropriate wording to be specified by the manufacturer).In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.This material and its container must be disposed of as hazardous waste

TSCA
否

C39990Alfa AesarMono-Ethyl malonate95%743元/5g;   2417元/25g;   20664元/250g;   展开

基本信息

Ref#
39990

MDL
20490

分子式
C5 H8 O4

分子量
132.11

密度
1119

445088Sigma-AldrichMono-Ethyl malonate397元/5 G;   展开

产品说明

应用

反应物用于：

  • 通过Dieckmann闭环方法制备特特拉姆酸
  • 有机催化脱羧Doebner-Knoevenagel反应
  • 与氨基修饰的寡核苷酸缀合
  • 酰化反应(酰化剂)
  • 用于潜在的朊病毒病治疗的吲哚乙醛酰胺
  • 与醛的Knoevenagel缩合反应

包装

5 g in glass bottle

其他说明

斯克里普斯代谢组学和质谱技术中心独立生成的串联质谱数据可在PDF 445088.pdf 中查看或下载。斯克里普斯代谢物组学和质谱技术中心的METLIN代谢物数据库中有测试代谢物。要了解更多信息，请访问sigma.com/metlin。

基本信息

线性分子式HO2CCH2CO2C2H5
分子量132.11
EC 号213-992-7
MDL编号MFCD00020490
PubChem化学物质编号24868159
NACRESNA.22

产品性质

杂质<10% ethyl malonate, potassium salt
折射率n20/D 1.435 (lit.)
bp106.5 ℃/3 mmHg (lit.)
密度1.119 g/mL at 25 ℃ (lit.)
SMILES stringCCOC(=O)CC(O)=O
InChI1S/C5H8O4/c1-2-9-5(8)3-4(6)7/h2-3H2,1H3,(H,6,7)
InChI keyHGINADPHJQTSKN-UHFFFAOYSA-N

安全信息

象形图GHS07
警示用语：Warning
危险声明H315 - H319 - H335
预防措施声明P302 + P352 - P305 + P351 + P338
危险分类Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官Respiratory system
储存分类代码10 - Combustible liquids
WGKWGK 3
闪点(F)235.4 °F - closed cup
闪点(C)113 ℃ - closed cup
个人防护装备Eyeshields, Gloves, type ABEK (EN14387) respirator filter
CAS号首数字顺序排列： 1 2 3 4 5 6 7 8 9