CAS 107-43-7; 甜菜素; betaine,anhydrous

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B992703

MACKLIN

甜菜碱溶液

5 M, PCR Reagent

368元/1.5ml; 920元/5ml; 2980元/25ml;

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储存：2-8°C
状态：液体

B802318

MACKLIN

甜菜碱,无水

分析对照品

216元/100mg;

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储存：室温
状态：白色到灰白色粉末

B794121

MACKLIN

甜菜碱,无水

10mM in DMSO

115元/1ml;

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储存：-20°C
状态：液体

B802319

MACKLIN

甜菜碱,无水

99%,超纯级

50元/5g; 182元/25g; 568元/100g; 1680元/500g; 4688元/2.5kg; 9999元/10kg;

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储存：室温
状态：白色到灰白色粉末

B802317

MACKLIN

甜菜碱,无水

98%

35元/50g; 80元/250g; 276元/1kg; 541元/2.5kg; 1799元/10kg;

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储存：室温
状态：白色到灰白色粉末

B0455

TCI

Betaine Anhydrous

>97.0%(T)

145元/25G; 295元/100G; 820元/500G;

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基本信息

纯度/分析方法	>97.0%(T)
分子式/分子量	C₅H₁₁NO₂ = 117.15
外观与形状(20℃)	固体
储存在惰性气体下	存放于惰性气体之中
应避免的情况	湿气 (吸湿)
Reaxys-RN	3537113
PubChem物质ID	87563491
Merck Index (14)	1179
MDL编号	MFCD00012123

技术规格

Appearance	White to Almost white powder to crystal
Purity(Nonaqueous Titration)	min. 97.0 %

物性(参考值)

熔点	300 ℃(dec.)

相关法规

RTECS#

DS5900000

214119

J&K

Betaine

98%

60元/5G; 283元/100G; 665元/500G;

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基本信息

分子式	C₅H₁₁NO₂
分子量	117.15
熔点	301
MDL编码	MFCD00012123
Beilstein	3537113
Merck	14,1179
EINECS 编号	203-490-6
存储条件	Store at 2-8℃

一般描述

甜菜碱是一种季铵盐，广泛存在于动植物和微生物中。它也是一种良好的食物来源，因为它在小麦，菠菜，贝类和甜菜均有发现。甜菜碱是氨基酸甘氨酸的甲基衍生物。它有不同的名字，如三甲基甘氨酸，甘氨酸甜菜碱，赖氨酸和三甲甘胺酸。

应用

甜菜碱对冷冻再生的抗氧化影响已得到研究。

生化/生理作用

甜菜碱是胆碱氧化代谢的终产物，是一种通用的甲基供体，特别存在于甲硫氨酸生物合成的一个次要途径中。它被用于治疗同型半胱氨酸尿症，一种在蛋氨酸生物合成主要途径的缺陷。甜菜碱除参与转甲基化外，还具有保护细胞在应激状态下的有机渗透作用。这在植物和微生物中得到了明显的观察。已知甜菜碱还可以增加 S-腺苷蛋氨酸的水平，从而可能减少肝脂肪变性的影响。

安全信息

防范说明	P262
WGK	3
RTECS	DS5900000
TSCA	是

B24397

Alfa Aesar

Betaine

anhydrous, 98%

467元/100g; 1604元/500g; 6017元/2500g;

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应用
Betaine is an active ingredient in toothpaste to control the symptoms of dryness of the mouth. It is used to treat homocystinuria, which is a defect in the major pathway of methionine biosynthesis. It is also used for boosting the immune system and for improving athletic performance. It is helpful to prevent noncancerous tumors in the colon (colorectal adenomas).

备注
Hygroscopic. Store in cool place. Incompatible with strong oxidizing agents.

基本信息

MDL
MFCD00012123

EINECS
203-490-6

分子式
(CH₃)₃NCH₂CO₂

分子量
117.15

熔点
>300° dec.

灵敏度
Hygroscopic. Ambient temperatures.

形态
Crystalline powder

溶解性
Soluble in water and methanol.

Beilstein
3537113

Merck
14,1179

安全信息

RTECS
DS5900000

TSCA
是

J77507

Alfa Aesar

Betaine

5M Solution, Molecular Biology Grade, Ultrapure, Thermo Scientific

2625元/10ml; 8492元/100ml;

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基本信息

MDL
MFCD00012123

EINECS
203-490-6

形态
Solution

Beilstein
3537113

安全信息

RTECS
DS5900000

TSCA
是

C20424

Alfa Aesar

Betaine

98%, for analysis, anhydrous

695元/5g; 944元/100g; 2503元/500g; 10361元/2.5kg;

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基本信息

Ref#
20424

MDL
12123

分子式
C5 H11 N O2

分子量
117.15

形态
White cryst powder

B2629

Sigma-Aldrich

Betaine

≥98% (perchloric acid titration)

504.13元/50 G; 645.18元/100 G; 2259.47元/1 KG;

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产品说明

一般描述

应用

甜菜碱对冷冻再生的抗氧化影响已得到研究。

包装

1 kg in poly bottle
50, 100 g in poly bottle

生化/生理作用

甜菜碱是胆碱氧化代谢的终产物，是一种通用的甲基供体，特别存在于甲硫氨酸生物合成的一个次要途径中。它被用于治疗同型半胱氨酸尿症，一种在蛋氨酸生物合成主要途径的缺陷。
甜菜碱除参与转甲基化外，还具有保护细胞在应激状态下的有机渗透作用。这在植物和微生物中得到了明显的观察。已知甜菜碱还可以增加 S-腺苷蛋氨酸的水平，从而可能减少肝脂肪变性的影响。

其他说明

Scripps Center for Metabolomics(斯克里普斯代谢组学中心)独立生成的串联质谱数据，可以PDF格式查看或下载。 B2629.pdf 已测代谢物收录于斯克里普斯代谢组学中心的代谢组学METLIN代谢物数据库中。更多信息请见sigma.com/metlin。

基本信息

线性分子式	(CH₃)₃N⁺CH₂COO^-
分子量	117.15
Beilstein	3537113
EC 号	203-490-6
MDL编号	MFCD00012123
PubChem化学物质编号	24891663
NACRES	NA.77

产品性质

生物来源	sugar beets
质量水平	200
测定	≥98% (perchloric acid titration)
形式	powder or crystals
mp	310 ℃ (dec.)
溶解性	water: 50 mg/mL, clear, colorless to faintly yellow
储存温度	2-8℃
SMILES string	C[N+](C)(C)CC([O-])=O
InChI	1S/C5H11NO2/c1-6(2,3)4-5(7)8/h4H2,1-3H3
InChI key	KWIUHFFTVRNATP-UHFFFAOYSA-N

安全信息

储存分类代码	11 - Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable
个人防护装备	Eyeshields, Gloves, type N95 (US)

W422312

Sigma-Aldrich

Betaine

≥98%

1230.3元/; 2224.65元/1 KG; 4818.59元/5 KG;

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产品说明

生化/生理作用

甜菜碱是胆碱氧化代谢的终产物，是一种通用的甲基供体，特别存在于甲硫氨酸生物合成的一个次要途径中。它被用于治疗同型半胱氨酸尿症，一种在蛋氨酸生物合成主要途径的缺陷。

基本信息

线性分子式	(CH₃)₃N⁺CH₂COO^-
分子量	117.15
FEMA编号	4223
Beilstein	3537113
MDL编号	MFCD00012123

产品性质

等级	Halal Kosher
reg. compliance	FDA 21 CFR 117
测定	≥98%
文件	see Safety & Documentation for available documents
性状检查	odorless
application(s)	flavors and fragrances
食品过敏原	no known allergens
SMILES string	C[N+](C)(C)CC([O-])=O
InChI	1S/C5H11NO2/c1-6(2,3)4-5(7)8/h4H2,1-3H3
InChI key	KWIUHFFTVRNATP-UHFFFAOYSA-N

安全信息

储存分类代码	11 - Combustible Solids
WGK	WGK 3

1065695

USP

Betaine

United States Pharmacopeia (USP) Reference Standard

3097.34元/1 G;

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产品说明

一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

生化/生理作用

分析说明

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.

其他说明

Sales restrictions may apply.

基本信息

线性分子式	(CH₃)₃N⁺CH₂COO^-
分子量	117.15
Beilstein	3537113
MDL编号	MFCD00012123
PubChem化学物质编号	329748928
NACRES	NA.24

产品性质

等级	pharmaceutical primary standard
manufacturer/tradename	USP
application(s)	pharmaceutical (small molecule)
格式	neat
SMILES string	C[N+](C)(C)CC([O-])=O
InChI	1S/C5H11NO2/c1-6(2,3)4-5(7)8/h4H2,1-3H3
InChI key	KWIUHFFTVRNATP-UHFFFAOYSA-N

安全信息

储存分类代码	13 - Non Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable

B0300

Sigma-Aldrich

Betaine solution

5 M, PCR Reagent

446.08元/1 VIAL; 1532.23元/5 VIALS;

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产品说明

一般描述

Betaine also called trimethylglycine or N,N,N triethylammonium acetate, is an analog of glycine with three methyl groups. It is highly compatible with polymerase chain reaction (PCR) buffer mixture. Betaine is a PCR enhancing reagent that is widely used for improving the yield and specificity of PCR products, especially during the PCR amplification of targets rich in GC content or those that form secondary structures resulting in poor yield. Betaine facilitates DNA strand separation and manages the DNA melting temperature (Tm) difference between the GC and AT pairs in DNA. It stabilizes the ds DNA by equalizing the contribution of GC- and AT-base pairs. Betaine has been broadly used to optimize multiplex and ‘long and accurate′ polymerase chain reaction (LA-PCR). The addition of 1.0-1.7 M aqueous betaine to a PCR mixture has been reported to reduce the base pair composition dependence on DNA strand melting.

应用

甜菜碱溶液已被用作以下组分

环介导等温扩增(LAMP)反应
用于基因组DNA扩增的聚合酶链式反应
用于端粒长度分析的定量聚合酶链式反应(qPCR)
PCR扩增基因组DNA之中的CGG重复片片段。

包装

每管1.5mL

基本信息

线性分子式	(CH₃)₃N⁺CH₂COO⁻
分子量	117.15
Beilstein	3537113
MDL编号	MFCD00012123
PubChem化学物质编号	24891511

产品性质

质量水平	300
等级	PCR Reagent
形式	liquid
包装	vial of 1.5 mL
浓度	5 M
technique(s)	PCR: suitable
颜色	colorless
application(s)	agriculture
异质活性	DNase, RNase, none detected
储存温度	2-8℃
SMILES string	C[N+](C)(C)CC([O-])=O
InChI	1S/C5H11NO2/c1-6(2,3)4-5(7)8/h4H2,1-3H3
InChI key	KWIUHFFTVRNATP-UHFFFAOYSA-N

安全信息

储存分类代码	12 - Non Combustible Liquids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable

61962

Sigma-Aldrich

Betaine

BioUltra, ≥99.0% (NT)

668.96元/50 G; 2786.58元/250 G;

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产品说明

应用

甜菜碱已被用于逆转录以增加蛋白质的热稳定性并使DNA螺旋脱稳。

生化/生理作用

甜菜碱是胆碱氧化代谢的终产物，是一种通用的甲基供体，特别存在于甲硫氨酸生物合成的一个次要途径中。它被用于治疗同型半胱氨酸尿症，一种在蛋氨酸生物合成主要途径的缺陷。
甜菜碱已被证明可增加S-腺苷甲硫氨酸(SAM)水平，因此可能在减少肝脏脂肪变性方面发挥作用。它是一种渗透压保护剂，可保护细胞免受环境压力的影响。

基本信息

线性分子式	(CH₃)₃N⁺CH₂COO^-
分子量	117.15
Beilstein	3537113
EC 号	203-490-6
MDL编号	MFCD00012123
PubChem化学物质编号	57651874
NACRES	NA.25

产品性质

产品线	BioUltra
质量水平	200
测定	≥99.0% (NT)
杂质	insoluble matters, passes filter test
溶解性	methanol: 1 M at 20 ℃, clear, colorless
痕量阴离子	chloride (Cl^-): ≤200 mg/kg sulfate (SO₄^2-): ≤200 mg/kg
痕量阳离子	Ca: ≤10 mg/kg Cd: ≤5 mg/kg Co: ≤5 mg/kg Cr: ≤5 mg/kg Cu: ≤5 mg/kg Fe: ≤5 mg/kg K: ≤50 mg/kg Mg: ≤5 mg/kg Mn: ≤5 mg/kg Na: ≤100 mg/kg Ni: ≤5 mg/kg Pb: ≤5 mg/kg Zn: ≤5 mg/kg
吸光度	≤0.05 at 280 nm in methanol at 1 M ≤0.08 at 260 nm in methanol at 1 M
SMILES string	C[N+](C)(C)CC([O-])=O
InChI	1S/C5H11NO2/c1-6(2,3)4-5(7)8/h4H2,1-3H3
InChI key	KWIUHFFTVRNATP-UHFFFAOYSA-N

安全信息

储存分类代码	11 - Combustible Solids
WGK	WGK 3
闪点(F)	Not applicable
闪点(C)	Not applicable
个人防护装备	Eyeshields, Gloves, type N95 (US)

462676

Fluorochem

Betaine

98%

352元/100g; 550元/250g; 1540元/1kg; 3520元/2.5kg;

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基本信息

CAS Number	107-43-7
MDL Number	MFCD00012123
Melting Point	>300℃

安全信息

图形或危害标志
危险性说明	H315: Causes skin irritation. H319: Causes serious eye irritation. H335: May cause respiratory irritation.
防范说明	P233: Keep container tightly closed. P260: Do not breathe . P261: Avoid breathing . P264: Wash hands thoroughly after handling. P271: Use only outdoors or in a well-ventilated area. P280: Wear . P302 + P352: IF ON SKIN: Wash with plenty of soap and water. P304: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.. P304 + P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing. P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P312: Call a POISON CENTER or doctor/physician if you feel unwell. P321: Specific treatment (see relevant procedures. on this label). P332 + P313: If skin irritation occurs: Get medical advice/ attention. P337 + P313: If eye irritation persists: Get medical advice/attention. P340: Remove victim to fresh air and keep at rest in a position comfortable for breathing. P362: Take off contaminated clothing and wash before reuse. P403: Store in a well-ventilated place. P403 + P233: Store in a well-ventilated place. Keep container tightly closed. P405: Store locked up. P501: Dispose of contents/container to in accordance with local regulation .