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CAS: 1068-90-2
分子式: C9H15NO5
分子量: 217.22
沸点: 185℃(20
熔点: 94-97℃
中文名称: 
乙酰胺基丙二酸二乙酯
二乙基乙酰胺与米酸酯
乙酰氨基丙二酸二乙酯
英文名称: 
Acetaminomalonic acid diethyl ester
acetamido-malonic aci diethyl ester
acetamidomalonic acid diethyl ester
diethyl 2-acetamidomalonate
diethyl acetamidomalonate
diethyl acetylaminomalonate
diethylester kyseliny acetylaminomalonove
diethylester kyseliny acetylaminomalonove (czech)
(acetylamino)-propanedioic aci diethyl ester
Diethyl Acetaminomalonate
Ethyl Acetamidomalonate
dlethyl acetamidomalonate
展开更多英文名
性质描述: 固体。熔点96.5-98℃,沸点185℃(2.67kPa)。溶于热醇,微溶于醚和热水。
生产方法: 由丙二酸二乙酯经亚硝化、还原、乙酰化而得。
用途: 用于α-氨基酸的合成,如作为色氨酸和消痛芥等的中间体。烷基化反应是合成氨基酸的关键反应之一,当该品与等摩尔氯苄混合,添加溴化四丁铵、碘化钠和粉状碳酸钾,于100℃搅拌5h时,冷却,过滤,水洗,干燥,得苄基乙酰氨基丙二酸二乙酯,收率92%。
推荐供应商
货号品牌产品名称规格包装、参考价格详情
D807880MACKLIN乙酰氨基丙二酸二乙酯98%29元/25g;   45元/100g;   199元/500g;   985元/2.5kg;   3719元/10kg;   展开
储存:室温
状态:白色或浅黄色粉末
D742811MACKLIN乙酰氨基丙二酸二乙酯Standard for GC, ≥99.7%(GC)128元/5g;   展开
储存:室温
状态:固体
A0015TCIDiethyl Acetamidomalonate>98.0%(GC)175元/25G;   320元/100G;   1200元/500G;   展开

基本信息

纯度/分析方法>98.0%(GC)
分子式/分子量C9H15NO5 = 217.22
外观与形状(20℃)固体
Reaxys-RN783883
PubChem物质ID87561720
SDBS (AIST Spectral DB)6508
MDL编号MFCD00009146

技术规格

AppearanceWhite to Almost white powder to crystal
Purity(GC)min. 98.0 %
Melting point95.0 to 99.0 ℃

物性(参考值)

熔点96 ℃

安全信息

信号词警告
危险性说明H303 : 吞咽可能有害。
防范说明P312 : 如感觉不适,呼叫急救中心/医生。

相关法规

RTECS#OO0360000
610979J&KDiethyl Acetamidomalonate99%65元/25G;   130元/100G;   343元/500G;   展开

基本信息

分子式C9H15NO5
分子量217.22
熔点95-98
沸点185
MDL编码MFCD00009146
Beilstein783883
EINECS 编号213-952-9

安全信息

图形或危害标志
提示语Warning
危险说明H303
防范说明P312
WGK3
RTECSOO0360000
TSCA
A14048Alfa AesarDiethyl Acetamidomalonate98+%407元/25g;   736元/100g;   3231元/500g;   展开

应用
Diethyl 2-Acetamidomalonate, is a versatile building block used for the synthesis of various pharmaceutical and biologically active compounds. It is an intermediate for the preparation of Novobiocin analogues as potential heat shock protein 90 inhibitors. It is also used as a important intermediates in syntheses of vitamins B1 and B6, barbiturates, non-steroidal anti-inflammatory agents, other numerous pharmaceuticals.

备注
Store in cool, dry place in tightly closed containers. Store away from oxidizing agent.

基本信息

MDL
MFCD00009146

EINECS
213-952-9

分子式
CH3CONHCH(CO2CH2CH3)2

分子量
217.22

熔点
96-99°

沸点
185°/20mm

灵敏度
Ambient temperatures.

形态
Crystalline powder

溶解性
Soluble in chloroform and methanol. Slightly soluble in water.

Beilstein
783883

安全信息

RTECS
OO0360000

TSCA

C11393Alfa AesarDiethyl Acetamidomalonate99+%395元/25g;   756元/100g;   3124元/500g;   展开

基本信息

Ref#
11393

MDL
9146

分子式
C9 H15 N O5

分子量
217.22

D84601Sigma-AldrichDiethyl Acetamidomalonate98%223.2元/25 G;   555.42元/100 G;   1783.07元/500 G;   展开

基本信息

线性分子式CH3CONHCH(CO2C2H5)2
分子量217.22
Beilstein783883
EC 号213-952-9
MDL编号MFCD00009146
PubChem化学物质编号24894215
NACRESNA.22

产品性质

质量水平100
测定98%
bp185 ℃/20 mmHg (lit.)
mp95-98 ℃ (lit.)
SMILES stringCCOC(=O)C(NC(C)=O)C(=O)OCC
InChI1S/C9H15NO5/c1-4-14-8(12)7(10-6(3)11)9(13)15-5-2/h7H,4-5H2,1-3H3,(H,10,11)
InChI keyISOLMABRZPQKOV-UHFFFAOYSA-N

安全信息

储存分类代码13 - Non Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
个人防护装备Eyeshields, Gloves, type N95 (US)
024267FluorochemDiethyl Acetamidomalonate98%330元/100g;   792元/250g;   1232元/500g;   展开

基本信息

CAS Number1068-90-2
MDL NumberMFCD00009146
Melting Point93-96℃

安全信息

图形或危害标志
危险性说明 H315: Causes skin irritation.
H319: Causes serious eye irritation.
H335: May cause respiratory irritation.
防范说明 P233: Keep container tightly closed.
P260: Do not breathe .
P261: Avoid breathing .
P264: Wash hands thoroughly after handling.
P271: Use only outdoors or in a well-ventilated area.
P280: Wear .
P302 + P352: IF ON SKIN: Wash with plenty of soap and water.
P304: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing..
P304 + P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P312: Call a POISON CENTER or doctor/physician if you feel unwell.
P321: Specific treatment (see relevant procedures. on this label).
P332 + P313: If skin irritation occurs: Get medical advice/ attention.
P337 + P313: If eye irritation persists: Get medical advice/attention.
P340: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P362: Take off contaminated clothing and wash before reuse.
P403: Store in a well-ventilated place.
P403 + P233: Store in a well-ventilated place. Keep container tightly closed.
P405: Store locked up.
P501: Dispose of contents/container to in accordance with local regulation .
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