| CAS: | 105016-65-7 | ||
| 中文名称: |
| ||
| 英文名称: |
|
| 货号 | 品牌 | 产品名称 | 规格 | 包装、参考价格 | |||||||||||||||||||||||||||||||||||||||||
| SMB00960 | Sigma-Aldrich | Etoposide quinone | 2016.33元/25 MG; 12097.8元/250 MG; | 咨询 | |||||||||||||||||||||||||||||||||||||||||
产品说明 一般描述 Etoposide-quinone is a major metabolite of anticancer drug etoposide, which may contribute to the development of secondary acute myeloid leukemias in some etoposide patients. Etoposide-quinone is a covalent poison of human topoisomerase IIb, which induces four times more topoisomerase IIb mediated DNA cleavage than etoposide. Etoposide-quinone is a potent (IC50 = 7 μM) irreversible inhibitor of TCPTP protein tyrosine phosphatase that increases STAT1 tyrosine phosphorylation and contributes to etoposide dependent leukemogenesis. 应用 Application: Metabolomics 基本信息
产品性质
安全信息
| |||||||||||||||||||||||||||||||||||||||||||||
m.cnreagent.com
