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CAS: 104-04-1
分子式: C8H8N2O3
分子量: 180.16
熔点: 212-217℃
中文名称: 
4-硝基乙酰苯胺
对硝基乙酰苯胺
4'-硝基乙酰苯胺
英文名称: 
acetanilide,4'-nitro-
acetamide,N-(4-nitrophenyl)-
N-(4-Nitro-phenyl)-acetamide
N-(4-Nitrophenyl)acetic acid amide
p-nitro-acetanilid
4'-nitroacetanilide
4-nitroacetanilide
n-(4-nitrophenyl)-acetamid
n-(4-nitrophenyl)acetamide
p-acetamidonitrobenzene
p-nitroacetanilide
展开更多英文名
性质描述: 白色棱状结晶。熔点215-216(207℃),沸点100℃(1.06×10-3kPa)。溶于热水、醇、醚,溶于氢氧化钾溶液成橙色,几乎不溶于冷水。
生产方法: 由乙酰苯胺经硝化制得。将98%的硫酸675kg加入硝化锅内,搅拌,并在20-25℃,2-2.5h内加入99%的乙酰苯胺225kg。待全部溶解后,降温至7℃,在4-7℃约20h内滴加混酸(由63kg水、60kg98%硫酸及107kg96%硝酸配成)。滴加完毕,稀释于4000L冰水中,静置1h。虹吸分离上层废酸,将下层物料过滤,用水洗至中性,即得4-硝基乙酰苯胺。另一种制法是用对硝基苯胺经乙酰化而得。
用途: 用作药物和染料的中间体。
推荐供应商
货号品牌产品名称规格包装、参考价格详情
N838405MACKLIN对硝基乙酰苯胺≥98%36元/1g;   68元/5g;   230元/25g;   712元/100g;   展开
储存:室温
状态:黄色到棕色粉末
N0108TCI4'-Nitroacetanilide>99.0%(GC)590元/25G;   4390元/500G;   展开

基本信息

纯度/分析方法>99.0%(GC)
分子式/分子量C8H8N2O3 = 180.16
外观与形状(20℃)固体
Reaxys-RN2211962
PubChem物质ID87573497
SDBS (AIST Spectral DB)10743
Merck Index (14)6581
MDL编号MFCD00007303

技术规格

AppearanceWhite to Amber to Dark green powder to crystal
Purity(GC)min. 99.0 %
Melting point213.0 to 217.0 ℃

物性(参考值)

熔点215 ℃

安全信息

图形或危害标志
信号词警告
危险性说明H315 : 造成皮肤刺激。
H319 : 造成严重眼刺激。
防范说明P264 : 作业后彻底清洗皮肤。
P280 : 戴防护手套/戴防护眼罩/戴防护面具。
P302 + P352 : 如皮肤沾染:用水充分清洗。
P337 + P313 : 如仍觉眼刺激:求医/就诊。
P305 + P351 + P338 : 如进入眼睛:用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出,取出隐形眼镜。继续冲洗。
P362+P364 : 脱掉沾污的衣服,清洗后方可重新使用。
P332 + P313 : 如发生皮肤刺激:求医/就诊。

相关法规

RTECS#AE5075000
A13539Alfa Aesar4'-Nitroacetanilide98%320元/5g;   1008元/25g;   展开

基本信息

MDL
MFCD00007303

EINECS
203-169-0

分子式
C8H8N2O3

分子量
180.16

熔点
215-217°

形态
Powder

Beilstein
2211962

Merck
14,6581

GHS危害和防范说明

GHS符号

Hazard Statements
H315-H319-H335
Causes skin irritation.Causes serious eye irritation.May cause respiratory irritation.

Precautionary Statements
P261-P280a-P305+P351+P338-P304+P340-P405-P501a
Avoid breathing dust/fume/gas/mist/vapours/spray.Wear protective gloves and eye/face protection.IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing.Store locked up.Dispose of contents/container in accordance with local/regional/national/international regulations.

安全信息

危险类别
36/37/38
Irritating to eyes, respiratory system and skin.

安全等级
26-37
In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.

RTECS
AE5075000

TSCA

C41575Alfa Aesar4'-Nitroacetanilide99%1565元/25g;   3734元/100g;   18940元/500g;   展开

基本信息

Ref#
41575

MDL
7303

分子式
C8 H8 N2 O3

分子量
180.16

130648Sigma-Aldrich4-Nitroacetanilide98%290.98元/5 G;   展开

产品说明

应用

4-硝基乙酰苯胺可被用作检测底物,而其水解是通过UV光谱测量而确定的。它还被用于制备4-氨基乙酰苯胺。

包装

5 g in glass bottle

基本信息

线性分子式CH3CONHC6H4NO2
分子量180.16
Beilstein2211962
EC 号203-169-0
MDL编号MFCD00007303
PubChem化学物质编号24847974
NACRESNA.22

产品性质

质量水平100
测定98%
mp213-215 ℃ (lit.)
SMILES stringCC(=O)Nc1ccc(cc1)[N+]([O-])=O
InChI1S/C8H8N2O3/c1-6(11)9-7-2-4-8(5-3-7)10(12)13/h2-5H,1H3,(H,9,11)
InChI keyNQRLPDFELNCFHW-UHFFFAOYSA-N

安全信息

象形图GHS07
警示用语:Warning
危险声明H315 - H319 - H335
预防措施声明P302 + P352 - P305 + P351 + P338
危险分类Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官Respiratory system
储存分类代码11 - Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
个人防护装备dust mask type N95 (US), Eyeshields, Gloves
038239Fluorochem4-Nitroacetanilide98%220元/1g;   396元/10g;   792元/25g;   1430元/50g;   2354元/100g;   展开

基本信息

CAS Number104-04-1
MDL NumberMFCD00007303
Melting Point212-218 ℃

安全信息

图形或危害标志
危险性说明 H315: Causes skin irritation.
H319: Causes serious eye irritation.
H335: May cause respiratory irritation.
防范说明 P233: Keep container tightly closed.
P260: Do not breathe .
P261: Avoid breathing .
P264: Wash hands thoroughly after handling.
P271: Use only outdoors or in a well-ventilated area.
P280: Wear .
P302 + P352: IF ON SKIN: Wash with plenty of soap and water.
P304: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing..
P304 + P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P312: Call a POISON CENTER or doctor/physician if you feel unwell.
P321: Specific treatment (see relevant procedures. on this label).
P332 + P313: If skin irritation occurs: Get medical advice/ attention.
P337 + P313: If eye irritation persists: Get medical advice/attention.
P340: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P362: Take off contaminated clothing and wash before reuse.
P403: Store in a well-ventilated place.
P403 + P233: Store in a well-ventilated place. Keep container tightly closed.
P405: Store locked up.
P501: Dispose of contents/container to in accordance with local regulation .
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