CAS 103-81-1; 苯乙酰胺; Phenylacetamide

CAS:

103-81-1

分子式:

C8H9NO

分子量:

135.16

沸点:

280-290 °C

熔点:

156 °C

中文名称:

苯乙酰胺

α-苯乙酰胺

英文名称:

Phenylacetamide

Benzeneacetamide

.alpha.-Toluamide

2-phenyl-acetamide

2-phenyl-acetamid

2-phenylacetamide

alpha-phenylacetamide

alpha-toluamide

alpha-toluimidic acid

phenyl-beta-acetylamine

phenylacetic acid amide

Phenacetamide

-Toluamide

展开更多英文名

性质描述:

白色片状或叶状结晶。熔点157-158℃，沸点280-290（分解）。溶于热水和乙醇，微溶于冷水、乙醚和苯。遇碱分解而析出氨。

生产方法:

将苯乙烯、硫磺、液氨和水投入高压釜，于165℃、约6.5MPa压力下反应，然后加热蒸发赶去硫化氢气体，加活性炭脱色、冷却、结晶、甩滤、干燥而得苯乙酰胺。此法可改进为管道化连续生产，将苯乙烯与多硫化铵液按体积比1:2配合，通过高压管道，反应温度为200℃，反应压力为6-7.8MPa，反应时间为1.5h。反应产物的后处理工艺过程与高压釜间歇法相似。原料消耗定额：苯乙烯（99%）1117kg/t、硫磺（98.5%）716kg/t、液氨（99%）539kg/t、活性炭47kg/t。另一种生产方法是将苯乙腈（由氯化苄和氰化钠在二甲胺水溶液中反应得到）在硫酸或盐酸中加热水解。将苯乙腈加入浓盐酸，搅拌溶解，在50℃反应半小时。然后在冷却下缓缓加入水析出结晶，冷却后过滤，用冰水洗涤即得粗品。粗品用碳酸钠溶液洗涤，再用冰水洗涤，干燥后可得较纯的苯乙酰胺。原料消耗定额：氯化苄（95%）1190kg/t、氰化钠（95%）527kg/t、二甲胺（工业品）20kg/t、碳酸钠（工业品）185kg/t、硫酸（92.5%）1760kg/t。

用途:

该品用作医药、农药、香料的中间体。在医药工业中是青霉素G的培养基和镇静药物苯巴比妥的原料。

推荐供应商

货号

品牌

产品名称

规格

包装、参考价格

详情

P795325

MACKLIN

2-苯基乙酰胺

10mM in DMSO

185元/1ml;

展开

储存：-20°C

P824601

MACKLIN

2-苯基乙酰胺

98%

30元/5g; 40元/25g; 80元/100g; 241元/500g;

展开

储存：室温
状态：白色片状或叶状晶体
折射率：1.552

P0120

TCI

2-Phenylacetamide

>98.0%(N)

495元/25G; 990元/100G; 3290元/500G;

展开

基本信息

纯度/分析方法	>98.0%(N)
分子式/分子量	C₈H₉NO = 135.17
外观与形状(20℃)	固体
Reaxys-RN	507886
PubChem物质ID	87574375
SDBS (AIST Spectral DB)	2682
Merck Index (14)	7266
MDL编号	MFCD00059193

技术规格

Appearance	White to Almost white powder to crystal
Purity(with Total Nitrogen)	min. 98.0 %
Melting point	156.0 to 161.0 ℃

物性(参考值)

熔点

156 ℃

相关法规

RTECS#

AC7705000

439749

J&K

2-Phenylacetamide

98%

91元/5G; 252元/25G; 833元/100G;

展开

基本信息

分子式	C₈H₉NO
分子量	135.17
熔点	156-161
MDL编码	MFCD00059193
Beilstein	507886
EINECS 编号	203-147-0

安全信息

图形或危害标志
提示语	Warning
危险说明	H301 H319
防范说明	P280 P301+P310 P305+P351+P338 P321 P405 P501a
WGK	3
RTECS	AC7705000

H60626

Alfa Aesar

2-Phenylacetamide

99%

513元/250mg;

展开

应用
It is used as a pharmaceutical intermediate.

备注
Store at 4?°C.

基本信息

MDL
MFCD00059193

EINECS
203-147-0

分子式
C₈H₉NO

分子量
135.17

灵敏度
Ambient temperatures.

形态
Solid

溶解性
Soluble in methanol.

GHS危害和防范说明

GHS符号

Hazard Statements
H302-H319
Harmful if swallowed.Causes serious eye irritation.

Precautionary Statements
P280i-P264-P305+P351+P338-P301+P312a-P337+P313-P501a
Wear eye/face protection.Wash thoroughly after handling.IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.If eye irritation persists: Get medical advice/attention.Dispose of contents/container in accordance with local/regional/national/international regulations.

安全信息

危险类别
22-36
Harmful if swallowed.Irritating to eyes.

安全等级
26-36-60
In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.Wear suitable protective clothing.This material and its container must be disposed of as hazardous waste

欧盟危险品标志

RTECS
AC7705000

TSCA
是

018952

Fluorochem

2-Phenylacetamide

99%

220元/1g; 264元/25g; 814元/100g;

展开

基本信息

CAS Number	103-81-1
MDL Number	MFCD00059193
Melting Point	156℃

安全信息

图形或危害标志
危险性说明	H315: Causes skin irritation. H319: Causes serious eye irritation. H335: May cause respiratory irritation.
防范说明	P233: Keep container tightly closed. P260: Do not breathe . P261: Avoid breathing . P264: Wash hands thoroughly after handling. P271: Use only outdoors or in a well-ventilated area. P280: Wear . P302 + P352: IF ON SKIN: Wash with plenty of soap and water. P304: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.. P304 + P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing. P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P312: Call a POISON CENTER or doctor/physician if you feel unwell. P321: Specific treatment (see relevant procedures. on this label). P332 + P313: If skin irritation occurs: Get medical advice/ attention. P337 + P313: If eye irritation persists: Get medical advice/attention. P340: Remove victim to fresh air and keep at rest in a position comfortable for breathing. P362: Take off contaminated clothing and wash before reuse. P403: Store in a well-ventilated place. P403 + P233: Store in a well-ventilated place. Keep container tightly closed. P405: Store locked up. P501: Dispose of contents/container to in accordance with local regulation .