| 货号 | 品牌 | 产品名称 | 规格 | 包装、参考价格 | 详情 |
| H835418 | MACKLIN | 6(5H)-菲啶酮 | 98% | 28元/1g; 47元/5g; 176元/25g; 647元/100g; | 展开 |
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| P1998 | TCI | 6(5H)-Phenanthridinone | >98.0%(HPLC)(N) | 150元/1G; 590元/5G; | 展开 |
基本信息 | 纯度/分析方法 | >98.0%(HPLC)(N) | | 分子式/分子量 | C13H9NO = 195.22 | | 外观与形状(20℃) | 固体 | | Reaxys-RN | 140641 | | PubChem物质ID | 160871399 | | MDL编号 | MFCD00004988 |
技术规格 | Appearance | White to Light yellow to Light orange powder to crystal | | Purity(HPLC) | min. 98.0 area% | | Purity(with Total Nitrogen) | min. 98.0 % |
物性(参考值) | 熔点 | 295 ℃ | | 最大吸收波长 | 338(EtOH) nm |
相关法规 |
| 473694 | J&K | 6-(5H)-Phenanthridinone | 98% | 352元/1G; 1292元/5G; | 展开 |
基本信息 | 分子式 | C13H9NO | | 分子量 | 195.22 | | 熔点 | 290-292 | | MDL编码 | MFCD00004988 | | Beilstein | 140641 | | EINECS 编号 | 213-804-3 | | 存储条件 | Store at 2-8℃ |
安全信息 | 防范说明 | P262 | | WGK | 3 | | RTECS | SG0370000 | | TSCA | 否 |
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| B25187 | Alfa Aesar | 6(5H)-Phenanthridinone | 96% | 862元/1g; 3759元/5g; | 展开 |
应用
6(5H)-Phenanthridinone is used as a probe into the role of PARP in cellular response to irradiation. Treatment of cells with 6(5H)-Phenanthridinone and various DNA-damaging agents showed a resistance to apoptosis. It acts as a reactant in the synthesis of 5,6-dihydrophenanthridine sulfonamides, oxidative coupling with diphenylacetylene, direct copper acetate-catalyzed N-cyclopropylation of cyclic amides. It is used as HIV-1 integrase inhibitor. 备注
Incompatible materials are oxidizing agents. Store in cool place. Keep container tightly closed in a dry and well-ventilated place. 基本信息 MDL
MFCD00004988 EINECS
213-804-3 分子式
C13H9NO 分子量
195.22 熔点
288-294° 灵敏度
Ambient temperatures. 形态
Powder 溶解性
Soluble in DMSO (5 mg/ml). Insoluble in water. Beilstein
140641 安全信息 RTECS
SG0370000 TSCA
否 |
| 299634 | Sigma-Aldrich | 6-(5H)-Phenanthridinone | technical grade | 308.6元/1 G; | 展开 |
产品说明 一般描述 6-(5H)-Phenanthridinone is an inhibitor of poly(ADP-ribose)polymerase (PARP)-1 activity. The ability of 6-(5H)-phenanthridinone to potentiate the effect of ionizing radiation on tumour cells was evaluated. Action of 6-(5H)-phenanthridinone, one of the most potent PARP inhibitor, on RDM4 murine lymphoma cells in culture was evaluated. 应用 Reactant involved in: - Synthesis of 5,6-dihydrophenanthridine sulfonamides
- Oxidative coupling with diphenylacetylene
- Direct copper acetate-catalyzed N-cyclopropylation of cyclic amides
Reactant involved in the synthesis and/or pharmacological activity of biologically active molecules including: - Potassium channel KV1.3 and IK-1 inhibitors
- HIV-1 integrase inhibitors
包装 1 g in glass bottle 基本信息 | 经验(实验)分子式 | C13H9NO | | 分子量 | 195.22 | | EC 号 | 213-804-3 | | MDL编号 | MFCD00004988 | | PubChem化学物质编号 | 24858050 | | NACRES | NA.22 |
产品性质 | 等级 | technical grade | | 质量水平 | 100 | | mp | 290-292 ℃ (lit.) | | SMILES string | O=C1Nc2ccccc2-c3ccccc13 | | InChI | 1S/C13H9NO/c15-13-11-7-2-1-5-9(11)10-6-3-4-8-12(10)14-13/h1-8H,(H,14,15) | | InChI key | RZFVLEJOHSLEFR-UHFFFAOYSA-N | | Gene Information | human ... PARP1(142) |
安全信息 | 储存分类代码 | 13 - Non Combustible Solids | | WGK | WGK 3 | | 闪点(F) | Not applicable | | 闪点(C) | Not applicable | | 个人防护装备 | Eyeshields, Gloves, type N95 (US) |
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| 077618 | Fluorochem | 6(5H)-Phenanthridinone | 95% | 220元/1g; 616元/5g; 1056元/10g; 2002元/25g; | 展开 |
基本信息 | CAS Number | 1015-89-0 | | MDL Number | MFCD00004988 |
安全信息 | 图形或危害标志 |  | | 危险性说明 | H302: Harmful if swallowed.
H315: Causes skin irritation.
H319: Causes serious eye irritation.
H332: Harmful if inhaled.
H335: May cause respiratory irritation.
| | 防范说明 | P233: Keep container tightly closed.
P260: Do not breathe .
P261: Avoid breathing .
P264: Wash hands thoroughly after handling.
P270: Do not eat, drink or smoke when using this product.
P271: Use only outdoors or in a well-ventilated area.
P280: Wear .
P301 + P312: IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell.
P302 + P352: IF ON SKIN: Wash with plenty of soap and water.
P304: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing..
P304 + P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P312: Call a POISON CENTER or doctor/physician if you feel unwell.
P321: Specific treatment (see relevant procedures. on this label).
P330: Rinse mouth.
P332 + P313: If skin irritation occurs: Get medical advice/ attention.
P337 + P313: If eye irritation persists: Get medical advice/attention.
P340: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P362: Take off contaminated clothing and wash before reuse.
P403: Store in a well-ventilated place.
P403 + P233: Store in a well-ventilated place. Keep container tightly closed.
P405: Store locked up.
P501: Dispose of contents/container to in accordance with local regulation .
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