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CAS: 1011-65-0
分子式: C10H9NO2
分子量: 175.18
熔点: 126-128 °C(lit.)
中文名称: 
吲哚-5-甲酸甲酯
英文名称: 
indole-5-carboxylic acid methyl ester
Methyl indole-5-carboxylate
1H-Indole-5-carboxylic acid methyl ester
性质描述: 该品为类白色粉末。熔点126-128℃。
推荐供应商
货号品牌产品名称规格包装、参考价格详情
M827746MACKLIN吲哚-5-甲酸甲酯≥95%96元/5g;   387元/25g;   展开
储存:室温
I0545TCIMethyl Indole-5-carboxylate>98.0%(GC)295元/1G;   1180元/5G;   展开

基本信息

纯度/分析方法>98.0%(GC)
分子式/分子量C10H9NO2 = 175.19
外观与形状(20℃)固体
Reaxys-RN474256
PubChem物质ID87571892
SDBS (AIST Spectral DB)41003
MDL编号MFCD00153023

技术规格

AppearanceWhite to Gray to Brown powder to crystal
Purity(GC)min. 98.0 %
Melting point125.0 to 129.0 ℃

物性(参考值)

熔点126 ℃

安全信息

图形或危害标志
信号词警告
危险性说明H315 : 造成皮肤刺激。
H319 : 造成严重眼刺激。
防范说明P264 : 作业后彻底清洗皮肤。
P280 : 戴防护手套/戴防护眼罩/戴防护面具。
P302 + P352 : 如皮肤沾染:用水充分清洗。
P337 + P313 : 如仍觉眼刺激:求医/就诊。
P305 + P351 + P338 : 如进入眼睛:用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出,取出隐形眼镜。继续冲洗。
P362+P364 : 脱掉沾污的衣服,清洗后方可重新使用。
P332 + P313 : 如发生皮肤刺激:求医/就诊。
465591J&KMethyl Indole-5-carboxylate97%107元/1G;   305元/5G;   展开

基本信息

分子式C10H9NO2
分子量175.18
熔点126-128
MDL编码MFCD00153023
Beilstein474256

安全信息

图形或危害标志
提示语Warning
危险说明H315
H319
H335
防范说明P261
P305+P351+P338
WGK3
TSCA
L16228Alfa AesarMethyl Indole-5-carboxylate97%596元/1g;   2701元/5g;   展开

应用
Reactant for biosynthesis of inhibitors of protein kinases, reactant in metal-free Friedel-Crafts alkylation, reactant in preparation of diphenylsulfonium ylides from Martin?s sulfurane, reactant in cross dehydrogenative coupling reactions, reactant in synthesis of indirubin derivatives, reactant in preparation of aminoindolylacetates.

备注
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from strong oxidizing agents.

基本信息

MDL
MFCD00153023

EINECS
000-000-0

分子式
C10H9NO2

分子量
175.19

熔点
123-126°

灵敏度
Ambient temperatures.

溶解性
Insoluble in water.

Beilstein
474256

GHS危害和防范说明

GHS符号

Hazard Statements
H315-H319-H335
Causes skin irritation.Causes serious eye irritation.May cause respiratory irritation.

Precautionary Statements
P261-P280a-P305+P351+P338-P304+P340-P405-P501a
Avoid breathing dust/fume/gas/mist/vapours/spray.Wear protective gloves and eye/face protection.IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing.Store locked up.Dispose of contents/container in accordance with local/regional/national/international regulations.

安全信息

危险类别
36/37/38
Irritating to eyes, respiratory system and skin.

安全等级
26-37
In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.

TSCA

511188Sigma-AldrichMethyl Indole-5-carboxylate99%287.54元/1 G;   715.1元/5 G;   展开

产品说明

一般描述

吲哚-5-甲酸甲酯(1H-吲哚-5-甲酸甲酯)是一种取代1H-吲哚,可以通过吲哚-5-羧酸的酯化反应进行制备。 已经评估了其作为靛类生成的底物的作用。

应用

吲哚-5-甲酸甲酯可用于制备:

  • 二氢吲哚-5-甲酸甲酯
  • 1H-吲哚-5-碳酰肼
  • 1H-吲哚-3,5-二羧酸二甲酯

吲哚-5-甲酸甲酯可用作以下过程的反应物:
  • 蛋白激酶抑制剂的生物合成
  • 无金属的Friedel-Crafts烷基化反应
  • 从Martin Sulfurane制备二苯基锍叶立德
  • 交叉脱氢偶联反应
  • 合成靛玉红衍生物
  • 制备氨基吲哚乙酸盐

包装

1, 5 g in glass bottle

基本信息

经验(实验)分子式C10H9NO2
分子量175.18
MDL编号MFCD00153023
PubChem化学物质编号24873426

产品性质

质量水平100
测定99%
mp126-128 ℃ (lit.)
SMILES stringCOC(=O)c1ccc2[nH]ccc2c1
InChI1S/C10H9NO2/c1-13-10(12)8-2-3-9-7(6-8)4-5-11-9/h2-6,11H,1H3
InChI keyDRYBMFJLYYEOBZ-UHFFFAOYSA-N

安全信息

象形图GHS07
警示用语:Warning
危险声明H315 - H319 - H335
预防措施声明P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
危险分类Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官Respiratory system
储存分类代码11 - Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
个人防护装备dust mask type N95 (US), Eyeshields, Gloves
016239FluorochemMethyl Indole-5-carboxylate98%264元/1g;   506元/5g;   902元/10g;   2068元/25g;   7216元/100g;   展开

基本信息

CAS Number1011-65-0
MDL NumberMFCD00153023
Melting Point126-128 ℃

安全信息

图形或危害标志
危险性说明 H315: Causes skin irritation.
H319: Causes serious eye irritation.
H335: May cause respiratory irritation.
防范说明 P233: Keep container tightly closed.
P260: Do not breathe .
P261: Avoid breathing .
P264: Wash hands thoroughly after handling.
P271: Use only outdoors or in a well-ventilated area.
P280: Wear .
P302 + P352: IF ON SKIN: Wash with plenty of soap and water.
P304: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing..
P304 + P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P312: Call a POISON CENTER or doctor/physician if you feel unwell.
P321: Specific treatment (see relevant procedures. on this label).
P332 + P313: If skin irritation occurs: Get medical advice/ attention.
P337 + P313: If eye irritation persists: Get medical advice/attention.
P340: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P362: Take off contaminated clothing and wash before reuse.
P403: Store in a well-ventilated place.
P403 + P233: Store in a well-ventilated place. Keep container tightly closed.
P405: Store locked up.
P501: Dispose of contents/container to in accordance with local regulation .
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