试剂仪器设备原料
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蛋白质/抗原/多肽 >> 重组蛋白
重组DOCK10蛋白
重组DOCK10蛋白图片
交货期: 1周
索取资料及报价
交货期:1周
产品别名:重组胞质分裂作用因子10(DOCK10)蛋白
Recombinant DOCK10
产品介绍
基因名:

DOCK10


产品别名:

DRIP2; Nbla10300; ZIZ3; DOCK10; dedicator of cytokinesis 10; dedicator of cytokinesis 10; dedicator of cytokinesis protein 10; dopamine receptor interacting protein 2; zizimin3; DOCK10蛋白; 胞质分裂作用因子10(DOCK10);


背景信息:
DOCK 10 is a 2,183 amino acid protein that belongs to the DOCK family of cytokinesis-regulating proteins and cotnains one PH domain, one DHR-1 domain and one DHR-2 domain. Expressed at lower levels in lung and brain tissue, DOCK 10 functions as a potential GEF (guanine nucleotide exchange factor) that is able to activate target GTPases by exchanging bound GDP for free GTP. Multiple isoforms of DOCK 10 exist due to alternative splicing events. The gene encoding DOCK 10 maps to human chromosome 2, which houses over 1,400 genes and comprises nearly 8% of the human genome. Harlequin icthyosis, a rare and morbid skin deformity, is associated with mutations in the ABCA12 gene, while the lipid metabolic disorder sitosterolemia is associated with defects in the ABCG5 and ABCG8 genes. Additionally, an extremely rare recessive genetic disorder, Alstr鰉 syndrome, is caused by mutations in the ALMS1 gene, which maps to chromosome 2.

标签:His-tag   
分类:Recombinant  
类型:Protein   
偶联物:Unconjugated
内毒素水平:按批次,参阅瓶身标签
性状:Liquid
浓度:Batch dependent (Please refer to the vial label for the specific concentration.)
纯化类型:purified
内含物:不含防腐剂
应用:Positive Control;Immunogen;SDS-PAGE;WB.
储存:2-8°C不超过一个月,-80°C不超过12个月。避免反复冻融。
注意事项:仅供实验室使用。不适用于人类或动物的任何临床,治疗或诊断用途。不适合动物或人类食用。

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