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半胱氨酸丰富血管生成诱导因子61(CYR61)抗体
产品介绍 靶标: CYR61 产品别名: CCN1; CYR61; cysteine rich angiogenic inducer 61; cysteine rich angiogenic inducer 61; CCN family member 1; Protein CEF-10; cellular communication network factor 1; protein CYR61; 半胱氨酸丰富血管生成诱导因子61(CYR61); 背景信息: Promotes cell proliferation, chemotaxis, angiogenesis and cell adhesion. Appears to play a role in wound healing by up-regulating, in skin fibroblasts, the expression of a number of genes involved in angiogenesis, inflammation and matrix remodeling including VEGA-A, VEGA-C, MMP1, MMP3, TIMP1, uPA, PAI-1 and integrins alpha-3 and alpha-5. CYR61-mediated gene regulation is dependent on heparin-binding. Down-regulates the expression of alpha-1 and alpha-2 subunits of collagen type-1. Promotes cell adhesion and adhesive signaling through integrin alpha-6 beta-1, cell migration through integrin alpha-v beta-5 and cell proliferation through integrin alpha-v beta-3. 宿主:Rbt |
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