| CAS: | 9002-08-8 | ||
| 英文名称: |
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| 货号 | 品牌 | 产品名称 | 规格 | 包装、参考价格 | 详情 | ||||||||||||||||||||||||||||||||||||||||||||||||
| T984946 | MACKLIN | 胰蛋白酶原 | ≥10,000 BAEE units/mg protein | 5100元/250mg; | 展开 | ||||||||||||||||||||||||||||||||||||||||||||||||
储存:-20°C, 密封, 干燥 状态:米色粉末 | |||||||||||||||||||||||||||||||||||||||||||||||||||||
| T9011 | Sigma-Aldrich | Trypsinogen, PMSF treated from bovine pancreas | For use as a marker in SDS-PAGE | 6000.59元/1 VIAL; | 展开 | ||||||||||||||||||||||||||||||||||||||||||||||||
产品说明 生化/生理作用 Hereditary pancreatitis was shown to be caused by a Arg-His substitution at residue 117 of trypsinogen causing auto-activation of trypsinogen to trypsin. 基本信息
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| T1143 | Sigma-Aldrich | Trypsinogen from bovine pancreas | essentially salt-free, lyophilized powder, ≥10,000 BAEE units/mg protein (E | 2380.16元/250 MG; 7849.85元/1 G; | 展开 | ||||||||||||||||||||||||||||||||||||||||||||||||
产品说明 一般描述 Trypsinogen is a proenzyme (zymogen) that is activated to form trypsin. It is synthesized in the pancreas and activated by enterokinase once it reaches the lumen of the small intestine. Bovine trypsinogen is a single polypeptide chain of 229 amino acids that is cross linked by six disulfide bridges. Enterokinase cleaves a hexapeptide to from the NH2 terminus of trypsinogen at the Lys6 - Ile7 peptide bond and activates it. Trypsin, thus formed, autocatalytically activates more trypsinogen to trypsin. This native form of trypsin is called β-trypsin, which undergoes autolysis at Lys131 - Ser132 resulting in α-trypsin that is held together by disulfide bridges. Trypsin is a serine protease with His46 and Ser183 at the active site. The pH optimum of trypsin is 7 - 9. 应用 Trypsinogen from bovine pancreas is suitable for use in:
包装 1 g in glass bottle 生化/生理作用 Phytic acid complexed with calcium has been shown to increase the secretion of trypsinogen unable to be cleaved for activation. It also reduced the stabilization effect of calcium on activated trypsin. The active form of trypsinogen, referred to as trypsin, cleaves peptides on the C-terminal side of lysine and arginine amino acid residues. It also hydrolyzes ester and amide linkages of synthetic derivatives of amino acids such as, benzoyl L-arginine ethyl ester (BAEE), p-toluenesulfonyl-L-arginine methyl ester (TAME), etc. 单位定义 One BAEE unit is equal to a ΔA253 of 0.001 per min with BAEE as substrate at pH 7.6 at 25 ℃ and a reaction volume of 3.2 mL (1 cm light path). 基本信息
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