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CAS: 90-64-2
分子式: C8H8O3
分子量: 152.15
熔点: 120-122℃
中文名称: 
2-羟基-2-苯基乙酸
苯乙醇酸
A-羟基苯乙酸
苯基乙醇酸
扁桃酸
苦杏仁酸
苯羟乙酸
α-羟基苯乙酸
alpha-羟基苯乙酸
英文名称: 
2-Hydroxy-2-phenylacetic acid
Amigdalinic acid
-Hydroxyben-zenacetic acid
Benzeneacetic acid,-hydroxy-
-Hydroxyphenylacetic acid
Mandelic acid
Amygdalic acid
.alpha.-hydroxy-Benzeneacetic acid
acido mandelico
alpha-hydroxy-alpha-toluic acid
(n)-Mandelic acid
alpha-hydroxyphenylacetic acid
alpha-hydroxy-alpha-toluic aci
alpha-hydroxy-benzeneacetic aci
phenyl-glycolic aci
kyselina 2-fenyl-2-hydroxyethanova
(+/-)-à-Hydroxyphenylacetic acid
kyselina mandlova
paramandelic acid
phenylglycolic acid
phenylhydroxyacetic acid
racemic mandelic acid
uromaline
Benzeneacetic acid,.alpha.-hydroxy-
DL-Amygdalic Acid
(±)-α-Hydroxyphenylacetic acid
展开更多英文名
性质描述: 白色斜方片状结晶,露置遇光变色分解。熔点119℃。相对密度 1.30。易溶于乙醚、异丙醇,溶于乙醇和水。R型熔点为133℃,[α]-159.73°(乙醇),于160℃ 逐渐外消旋化。S型 熔点为133.8℃ ,[α]+156.57°(水)。
生产方法: 1.以异丙苯法制苯酚的副产苯乙酮为原料,氯化得二氯苯乙酮,然后与稀碱反应、水解,制得扁桃酸。2.以苯甲醛为原料。将氰化钠溶于水中,加入苯甲醛,搅拌下慢慢加入亚硫酸氢钠的饱和溶液,加至一半时,加入碎冰,将析出的苯羟乙腈层从水层中分出。水层用苯萃取,蒸出苯,剩余物与苯羟乙腈层合并,加入盐酸,在冷却下水解12h。然后加热除去过量的水和盐酸,冷却,滤出氯化铵和扁桃酸的混合物。把滤液蒸干,剩余物与以上固体合并,用冷苯洗涤。再用热苯提取,提取液经冷却、结晶、过滤、干燥,即得扁桃酸,收率50-52%。3.苯-乙醛酸法。
用途: 在医药工业可用于头孢羟唑、血管扩张药环扁桃酸酯、滴眼药羟苄唑、匹莫林等的中间体,也可作防腐剂。
推荐供应商
货号品牌产品名称规格包装、参考价格详情
D813149MACKLINDL-扁桃酸98%66元/250g;   108元/500g;   535元/2.5kg;   展开
储存:室温,避光
状态:浅黄色粉末
D796922MACKLINDL-扁桃酸10mM in DMSO185元/1ml;   展开
储存:-20°C, 避光
D813148MACKLINDL-扁桃酸试剂级, 99.0%27元/25g;   52元/100g;   159元/500g;   631元/2.5kg;   展开
储存:室温,避光
状态:白色到浅黄色粉末
M0038TCIDL-Mandelic Acid>99.0%(GC)(T)190元/25G;   620元/500G;   展开

基本信息

纯度/分析方法>99.0%(GC)(T)
分子式/分子量C8H8O3 = 152.15
外观与形状(20℃)固体
Reaxys-RN510011
PubChem物质ID87572154
SDBS (AIST Spectral DB)10713
Merck Index (14)5717
MDL编号MFCD00064250

技术规格

AppearanceWhite to Almost white powder to crystal
Purity(GC)min. 99.0 %
Purity(Neutralization titration)min. 99.0 %
Melting point119.0 to 122.0 ℃

物性(参考值)

熔点121 ℃
溶解性(易溶于)乙醚,乙醇
溶解性(可溶于)甲醇,氯仿

安全信息

图形或危害标志
信号词警告
危险性说明H315 : 造成皮肤刺激。
H319 : 造成严重眼刺激。
防范说明P264 : 作业后彻底清洗皮肤。
P280 : 戴防护手套/戴防护眼罩/戴防护面具。
P302 + P352 : 如皮肤沾染:用水充分清洗。
P337 + P313 : 如仍觉眼刺激:求医/就诊。
P305 + P351 + P338 : 如进入眼睛:用水小心冲洗几分钟。如戴隐形眼镜并可方便地取出,取出隐形眼镜。继续冲洗。
P362+P364 : 脱掉沾污的衣服,清洗后方可重新使用。
P332 + P313 : 如发生皮肤刺激:求医/就诊。

相关法规

RTECS#OO6300000
343361J&KDL-Mandelic Acid99%60元/25G;   123元/100G;   413元/500G;   展开

基本信息

分子式C8H8O3
分子量152.15
熔点119-121
MDL编码MFCD00064250
Beilstein510011
Merck14,5717
EINECS 编号202-007-6

安全信息

WGK3
RTECSOO6300000
TSCA
A14223Alfa Aesar(±)-Mandelic acid99%286元/100g;   707元/500g;   3361元/2500g;   展开

应用
Mandelic acid is used in the pharmaceutical industry as an antibacterial to treat urinary tract infections. It acts as a precursor for making various drugs. It is also used as an oral antibiotic. Mandelic acid peels are widely used for treating damaged skin due to its less penetrating and irritating property. Enantiomeric resolution of (?±)-Mandelic acid is performed by using the chiral amine (1R,2S)-(-)-ephedrine followed by acidification to prepare (R)-( -)-Mandelic acid.

备注
Hydrophobic and light sensitive. Incompatible with strong oxidizing agents and reducing agents.

基本信息

MDL
MFCD00064250

EINECS
202-007-6

分子式
C8H8O3

分子量
152.15

熔点
118-121°

灵敏度
Light Sensitive. Ambient temperatures.

形态
Crystalline powder

溶解性
Soluble in water, diethyl ether, ethanol and isopropanol.

Beilstein
510011

Merck
14,5717

GHS危害和防范说明

GHS符号

Hazard Statements
H318
Causes serious eye damage.

Precautionary Statements
P280i-P305+P351+P338-P310a
Wear eye/face protection.IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

安全信息

危险类别
41
Risk of serious damage to eyes.

安全等级
26-39-60
In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.Wear eye/face protection.This material and its container must be disposed of as hazardous waste

RTECS
OO6300000

TSCA

C12531Alfa AesarDL-Mandelic Acid99+%455元/100g;   862元/250g;   2536元/1kg;   9627元/5kg;   展开

基本信息

Ref#
12531

MDL
64250

分子式
C8 H8 O3

分子量
152.15

形态
White cryst powder

8.06913Sigma-AldrichDL-Mandelic Acidfor synthesis575.89元/250 G;   1900.8元/1 KG;   展开

产品说明

分析说明

含量(酸度): ≥ 99,0 %(m)
熔程(下限值): ≥ 116 °C
熔程(上限值): ≤ 121 °C
同一性(IR):符合

基本信息

线性分子式C6H5CH(OH)COOH
分子量152.15
MDL编号MFCD00064250
EC索引号210-277-1

产品性质

质量水平200
蒸汽压0.01 Pa ( 50 ℃)
测定≥99.0% (acidimetric)
形式crystals
pH值(酸碱度)2.3 (10 g/L in H2O)
mp119-121 ℃
溶解性 139 g/L
密度1.31 g/cm3 at 20.2 ℃
堆积密度750 kg/m3
储存温度2-30℃
InChI1S/C8H8O3/c9-7(8(10)11)6-4-2-1-3-5-6/h1-5,7,9H,(H,10,11)
InChI keyIWYDHOAUDWTVEP-UHFFFAOYSA-N

安全信息

象形图GHS05
警示用语:Danger
危险声明H318
预防措施声明P280 - P305 + P351 + P338
危险分类Eye Dam. 1
储存分类代码13 - Non Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
M2101Sigma-AldrichMandelic acid99%519.17元/250 G;   767.44元/500 G;   展开

产品说明

应用

以扁桃酯形式存在的外消旋扁桃酸由于其镇痛、抗风湿、解痉作用,一般作为药用成分。它通过成盐拆分形成 (+)-和 (-)-对映体,广泛用作各种其他外消旋体的对映体拆分中的手性拆分剂。

包装

250, 500 g in poly bottle

基本信息

线性分子式C6H5CH(OH)CO2H
分子量152.15
EC 号202-007-6
MDL编号MFCD00064250
PubChem化学物质编号24896602
NACRESNA.22

产品性质

质量水平200
测定99%
mp119-121 ℃ (lit.)
SMILES stringOC(C(O)=O)c1ccccc1
InChI1S/C8H8O3/c9-7(8(10)11)6-4-2-1-3-5-6/h1-5,7,9H,(H,10,11)
InChI keyIWYDHOAUDWTVEP-UHFFFAOYSA-N

安全信息

象形图GHS05
警示用语:Danger
危险声明H318
预防措施声明P280 - P305 + P351 + P338
危险分类Eye Dam. 1
储存分类代码13 - Non Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
个人防护装备Eyeshields, Gloves, type N95 (US)
PHR3199SupelcoMandelic acidpharmaceutical secondary standard, certified reference material2006.37元/1 g;   展开

产品说明

一般描述

Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards

分析说明

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

其他说明

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

附注

To see an example of a Certificate of Analysis for this material enter LRAC7670 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

基本信息

线性分子式C6H5CH(OH)COOH
分子量152.15
Beilstein510011
MDL编号MFCD00064250

产品性质

等级certified reference material
pharmaceutical secondary standard
CofAcurrent certificate can be downloaded
包装pkg of 1 g
application(s)pharmaceutical
药典可追溯性traceable to USP 1375058
储存温度2-30℃
SMILES stringOC(C(O)=O)c1ccccc1
InChI1S/C8H8O3/c9-7(8(10)11)6-4-2-1-3-5-6/h1-5,7,9H,(H,10,11)
InChI keyIWYDHOAUDWTVEP-UHFFFAOYSA-N

安全信息

象形图GHS05
警示用语:Danger
危险声明H318
预防措施声明P280 - P305 + P351 + P338
危险分类Eye Dam. 1
储存分类代码13 - Non Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
1375058USPMandelic acidUnited States Pharmacopeia (USP) Reference Standard2829.07元/500 MG;   展开

产品说明

一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

分析说明

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

其他说明

USP issued SDS can be found here.
Sales restrictions may apply.

基本信息

线性分子式C6H5CH(OH)COOH
分子量152.15
Beilstein510011
MDL编号MFCD00064250
PubChem化学物质编号329750318
NACRESNA.24

产品性质

等级pharmaceutical primary standard
manufacturer/tradenameUSP
application(s)pharmaceutical (small molecule)
格式neat
SMILES stringOC(C(O)=O)c1ccccc1
InChI1S/C8H8O3/c9-7(8(10)11)6-4-2-1-3-5-6/h1-5,7,9H,(H,10,11)
InChI keyIWYDHOAUDWTVEP-UHFFFAOYSA-N

安全信息

象形图GHS05
警示用语:Danger
危险声明H318
预防措施声明P280 - P305 + P351 + P338
危险分类Eye Dam. 1
储存分类代码13 - Non Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
41605SupelcoDL-Mandelic acidanalytical standard1543.08元/100 MG;   展开

产品说明

一般描述

DL-扁桃酸是苯乙烯的芳烃代谢产物。

应用

DL-扁桃酸可用作测定以下样品中 DL-扁桃酸含量的分析参考标准:

  • 人尿样品,通过配备了紫外线(UV)检测器的高效液相色谱(HPLC)法检测。
  • 大鼠尿液样品,通过配备选定的离子监测(SIM)检测的气相色谱-质谱法(GC-MS)法检测。


有关合适的仪器技术的更多信息,请参阅产品的分析证书。想要获得更多支持,请联系技术服务部。

包装

无底玻璃瓶。内含物装在锥底内插管中。

基本信息

线性分子式C6H5CH(OH)COOH
分子量152.15
Beilstein510011
EC 号202-007-6
MDL编号MFCD00064250
PubChem化学物质编号329756123

产品性质

质量水平100
等级analytical standard
测定≥98.5% (HPLC)
旋光性[α]/D 0±1°, c = 5 in H2O
保质期limited shelf life, expiry date on the label
technique(s)HPLC: suitable
gas chromatography (GC): suitable
application(s)cleaning products
cosmetics
food and beverages
forensics and toxicology
personal care
veterinary
格式neat
SMILES stringOC(C(O)=O)c1ccccc1
InChI1S/C8H8O3/c9-7(8(10)11)6-4-2-1-3-5-6/h1-5,7,9H,(H,10,11)
InChI keyIWYDHOAUDWTVEP-UHFFFAOYSA-N

安全信息

象形图GHS05
警示用语:Danger
危险声明H318
预防措施声明P280 - P305 + P351 + P338
危险分类Eye Dam. 1
储存分类代码13 - Non Combustible Solids
WGKWGK 3
闪点(F)Not applicable
闪点(C)Not applicable
093723Fluorochem2-Hydroxy-2-phenylacetic acid95%220元/100g;   968元/500g;   展开

基本信息

CAS Number90-64-2
MDL NumberMFCD00064250

安全信息

图形或危害标志
危险性说明 H302: Harmful if swallowed.
H315: Causes skin irritation.
H319: Causes serious eye irritation.
H335: May cause respiratory irritation.
防范说明 P233: Keep container tightly closed.
P260: Do not breathe .
P261: Avoid breathing .
P264: Wash hands thoroughly after handling.
P270: Do not eat, drink or smoke when using this product.
P271: Use only outdoors or in a well-ventilated area.
P280: Wear .
P301 + P312: IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell.
P302 + P352: IF ON SKIN: Wash with plenty of soap and water.
P304: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing..
P304 + P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P312: Call a POISON CENTER or doctor/physician if you feel unwell.
P321: Specific treatment (see relevant procedures. on this label).
P330: Rinse mouth.
P332 + P313: If skin irritation occurs: Get medical advice/ attention.
P337 + P313: If eye irritation persists: Get medical advice/attention.
P340: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P362: Take off contaminated clothing and wash before reuse.
P403: Store in a well-ventilated place.
P403 + P233: Store in a well-ventilated place. Keep container tightly closed.
P405: Store locked up.
P501: Dispose of contents/container to in accordance with local regulation .
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