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CAS: 80-08-0
分子式: C12H12N2O2S
分子量: 248.30
熔点: 173-178℃
中文名称: 
4,4'-磺酰基双苯胺
4,4'-二氨基二苯砜
氨苯砜
4,4-二氨基苯砜
二氨基二苯砜
4,4'-二氨基联苯砜
英文名称: 
4,4'-sulfonyl bis-Benzenamine
4,4'-Diaminodiphenyl sulfone
Avlosulfone
4,4'-sulfonyldi-anilin
1,1'-sulfonylbis(4-aminobenzene)
1,1'-sulphonylbis(4-aminobenzene)
1358f
4,4'-diaminodiphenyl sulphone
4,4'-sulfonylbisaniline
4,4'-sulfonylbisbenzamine
4,4'-sulfonylbisbenzenamine
4,4'-sulfonyldianiline
4,4'-sulphonylbisbenzamine
4,4'-sulphonylbisbenzenamine
4,4'-sulphonyldianiline
4,4-diaminodifenylsulfon
avlosulfon
avlosulphone
4,4'-sulfonylbis-benzenamin
bis(4-aminophenyl) sulfone
bis(4-aminophenyl)sulphone
bis(p-aminophenyl) sulfone
bis(p-aminophenyl)sulphone
croysulfone
croysulphone
dadps
dapson
dapsone
dapsonum
dds (pharmaceutical)
dds [pharmaceutical]
di(4-aminophenyl)sulfone
di(4-aminophenyl)sulphone
di(p-aminophenyl) sulfone
di(p-aminophenyl)sulphone
diamino-4,4'-diphenyl sulfone
diamino-4,4'-diphenyl sulphone
diaminodifenilsulfona
diaphenylsulfon
diaphenylsulfone
bis(4-aminophenyl)sulfone
diaphenylsulphon
benzenamine,4,4'-sulfonylbis-
diaphenylsulphone
4,4'-diaminodiphenylsulphone
aniline,4,4'-sulfonyldi-
diphenasone
4,4'-dapsone
diphone
1,1'-sulfonylbis[4-aminobenzene]
disulone
4,4'-Diaminodiphenylsulfone
dubronax
dumitone
eporal
f 1358
metabolite c
nci-c01718
novophone
nsc 6091d
nsc-6091
,4'-diaminodiphenyl sulfone
p,p'-diaminodiphenyl sulfone
p,p'-sulfonyldianiline
Bis(3-aminophenyl)sulfone
p,p-diaminodiphenyl sulphone
p,p-sulfonylbisbenzamine
Benzenamine,4,4'-sulfonyl bis-
p,p-sulfonylbisbenzenamine
p,p-sulphonylbisbenzamine
p,p-sulphonylbisbenzenamine
p,p-sulphonyldianiline
sulfona
sulfona-mae
sulfone ucb
diphenyl, 4,4'-diamino-sulfon
sulphadione
sulphonyldianiline
sumicure s
tarimyl
udolac
wr 448
4-aminophenyl sulfone
展开更多英文名
推荐供应商
货号品牌产品名称规格包装、参考价格详情
D796201MACKLIN4,4'-二氨基二苯砜10mM in DMSO185元/1ml;   展开
储存:-20°C
状态:液体
D806904MACKLIN4,4'-二氨基二苯砜97%29元/50g;   39元/100g;   138元/500g;   266元/1kg;   629元/2.5kg;   展开
储存:室温,干燥,密封
状态:白色到米黄色粉末或晶体
D787407MACKLIN4,4'-二氨基二苯砜≥99%58元/100g;   168元/500g;   747元/2.5kg;   2700元/10kg;   展开
储存:RT,Dry,Seal
状态:白色到米黄色粉末或晶体
D708132MACKLIN4,4'-二氨基二苯砜97%, -1000目(≥90%)1898元/500g;   展开
储存:室温,干燥,密封
D0089TCIBis(4-aminophenyl) Sulfone>98.0%(T)(HPLC)100元/25G;   260元/100G;   775元/500G;   展开

基本信息

纯度/分析方法>98.0%(T)(HPLC)
分子式/分子量C12H12N2O2S = 248.30
外观与形状(20℃)固体
Reaxys-RN788055
PubChem物质ID87566830
SDBS (AIST Spectral DB)7075
Merck Index (14)2822
MDL编号MFCD00007887

技术规格

AppearanceWhite to Light yellow powder to crystal
Purity(HPLC)min. 98.0 area%
Purity(Nonaqueous Titration)min. 98.0 %
Melting point173.0 to 181.0 ℃
Solubility in hot Methanolalmost transparency

物性(参考值)

熔点177 ℃
水溶性不溶
在水中的溶解度380 mg/l   37 ℃
溶解性(可溶于)丙酮,醇

安全信息

图形或危害标志
信号词危险
危险性说明H302 : 吞咽有害。
H371 : 可能损害器官。
H372 : 长期或反复接触会对器官造成损害。
H373 : 长期或反复接触可能损害器官。
H411 : 对水生生物有毒并具有长期持续影响。
防范说明P501 : 将内装物/容器送到批准的废物处理厂处理。
P273 : 避免释放到环境中。
P260 : 不要吸入粉尘/ 烟/ 气体/ 烟雾/ 蒸气/ 喷雾。
P270 : 使用本产品时不要进食、饮水或吸烟。
P264 : 作业后彻底清洗皮肤。
P391 : 收集溢出物。
P308+P311 : 如接触到或有疑虑:呼叫急救中心/医生。
P301 + P312 + P330 : 如误吞咽:如感觉不适,呼叫急救中心/医生。漱口。
P405 : 存放处须加锁。

相关法规

RTECS#BY8925000

运输信息

UN编号UN3077
类别9
包装类别 III
监管条件代码(*)
142160J&K4,4'-Diaminodiphenyl Sulfone99.5%121元/25G;   400元/100G;   1206元/500G;   展开

基本信息

分子式C12H12N2O2S
分子量248.31
熔点175-177
MDL编码MFCD00007887
Beilstein788055
Merck14,2822
EINECS 编号201-248-4

安全信息

图形或危害标志
提示语Warning
危险说明H302
防范说明P301+P312
WGK1
RTECSBY8925000
TSCA
A18976Alfa Aesar4,4'-Diaminodiphenyl Sulfone98%960元/100g;   3416元/500g;   展开

应用
It is active against a wide range of bacteria, but is mainly employed for its actions against Mycobacterium leprae, being used as part of multidrug regimens in the treatment of all forms of leprosy. It is a second-line medication for the treatment and prevention of Pneumocystis pneumonia and for the prevention of toxoplasmosis in those who have poor immune function. Additionally, it has been used for acne as well as other skin conditions. Moreover it is employed as an anti-inflammatory drug, anti-infective drug, a leprostatic drug and an antimalarial drug.

备注
Store away from oxidizing agents. Keep the container tightly closed and place it in a cool, dry and well ventilated condition.

基本信息

MDL
MFCD00007887

EINECS
201-248-4

分子式
C12H12N2O2S

分子量
248.30

熔点
175-178°

灵敏度
Ambient temperatures.

形态
Powder

溶解性
Insoluble in water. Solubility in hot methanol is almost transparent. Soluble in DMSO, ethanol and acetone.

Beilstein
788055

Merck
14,2822

GHS危害和防范说明

GHS符号

Hazard Statements
H302
Harmful if swallowed.

Precautionary Statements
P261
Avoid breathing dust/fume/gas/mist/vapours/spray.

安全信息

危险类别
22
Harmful if swallowed.

安全等级
22
Do not breathe dust.

欧盟危险品标志

RTECS
BY8925000

TSCA

C10436Alfa Aesar4-Aminophenyl sulfone97%904元/100g;   487元/5g;   3417元/500g;   展开

基本信息

Ref#
10436

MDL
7887

分子式
C12 H12 N2 O2 S

分子量
248.3

形态
Powder

PHR1464SupelcoDapsonePharmaceutical Secondary Standard; Certified Reference Material919.94元/1 G;   展开

产品说明

一般描述

Dapsone is an antibacterial drug, belongs to a class of compounds known as sulfones. It acts by inhibiting the synthesis of dihydrofolic acid through competition with para-aminobenzoate for the active site of dihydropteroate synthetase, thereby inhibiting the growth of microorganisms that are dependent on endogenous folic acid synthesis. It is used in primary treatment of dermatitis herpetiformis and in combination with other drugs to treat leprosy.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

应用

Dapsone may be used as a pharmaceutical reference standard for the determination of the analyte in bulk drug and pharmaceutical formulations by chromatography.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

分析说明

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

其他说明

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

附注

To see an example of a Certificate of Analysis for this material enter LRAA3012 in the slot below. This is an example certificate only and may not be the lot that you receive.

基本信息

线性分子式(H2NC6H4)2SO2
分子量248.30
Beilstein788055
EC 号201-248-4
MDL编号MFCD00007887
PubChem化学物质编号329823395
NACRESNA.24

产品性质

质量水平300
等级certified reference material
pharmaceutical secondary standard
CofAcurrent certificate can be downloaded
包装pkg of 1 g
technique(s)HPLC: suitable
gas chromatography (GC): suitable
mp175-177 ℃ (lit.)
application(s)pharmaceutical (small molecule)
格式neat
药典可追溯性traceable to BP 102
traceable to PhEur D0100000
traceable to USP 1164008
储存温度2-30℃
SMILES stringNc1ccc(cc1)S(=O)(=O)c2ccc(N)cc2
InChI1S/C12H12N2O2S/c13-9-1-5-11(6-2-9)17(15,16)12-7-3-10(14)4-8-12/h1-8H,13-14H2
InChI keyMQJKPEGWNLWLTK-UHFFFAOYSA-N

安全信息

象形图GHS07GHS08GHS09
警示用语:Danger
危险声明H302 - H370 - H373 - H411
预防措施声明P260 - P264 - P270 - P273 - P301 + P312 - P308 + P311
危险分类Acute Tox. 4 Oral - Aquatic Chronic 2 - STOT RE 2 - STOT SE 1
靶器官Blood
储存分类代码6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGKWGK 1
46158SupelcoDapsoneVETRANAL®, analytical standard571.28元/250 MG;   展开

产品说明

一般描述

Dapsone is a synthetic antibiotic belonging to the class of sulfonamides, which show inhibitory action against most gram-positive and many gram-negative organisms.

应用

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Dapsone may be used as an analytical reference standard for the quantification of the analyte in animal samples and pharmaceutical formulations using different analytical techniques

法律信息

VETRANAL is a registered trademark of sigma-aldrich Chemie GmbH

基本信息

线性分子式(H2NC6H4)2SO2
分子量248.30
Beilstein788055
EC 号201-248-4
MDL编号MFCD00007887
PubChem化学物质编号329757089
NACRESNA.24

产品性质

等级analytical standard
质量水平200
产品线VETRANAL®
保质期limited shelf life, expiry date on the label
technique(s)HPLC: suitable
gas chromatography (GC): suitable
mp175-177 ℃ (lit.)
application(s)cleaning products
clinical
cosmetics
food and beverages
forensics and toxicology
personal care
pharmaceutical (small molecule)
格式neat
SMILES stringNc1ccc(cc1)S(=O)(=O)c2ccc(N)cc2
InChI1S/C12H12N2O2S/c13-9-1-5-11(6-2-9)17(15,16)12-7-3-10(14)4-8-12/h1-8H,13-14H2
InChI keyMQJKPEGWNLWLTK-UHFFFAOYSA-N

安全信息

象形图GHS07GHS08GHS09
警示用语:Danger
危险声明H302 - H370 - H373 - H411
预防措施声明P260 - P264 - P270 - P273 - P301 + P312 - P308 + P311
危险分类Acute Tox. 4 Oral - Aquatic Chronic 2 - STOT RE 2 - STOT SE 1
靶器官Blood
储存分类代码6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGKWGK 1
个人防护装备dust mask type N95 (US), Eyeshields, Gloves
1164008USPDapsoneUnited States Pharmacopeia (USP) Reference Standard3231.47元/200 MG;   展开

产品说明

一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

分析说明

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

其他说明

USP issued SDS can be found here.
Sales restrictions may apply.

基本信息

线性分子式(H2NC6H4)2SO2
分子量248.30
Beilstein788055
MDL编号MFCD00007887
PubChem化学物质编号329749522
NACRESNA.24

产品性质

等级pharmaceutical primary standard
manufacturer/tradenameUSP
mp175-177 ℃ (lit.)
application(s)pharmaceutical (small molecule)
格式neat
储存温度2-8℃
SMILES stringNc1ccc(cc1)S(=O)(=O)c2ccc(N)cc2
InChI1S/C12H12N2O2S/c13-9-1-5-11(6-2-9)17(15,16)12-7-3-10(14)4-8-12/h1-8H,13-14H2
InChI keyMQJKPEGWNLWLTK-UHFFFAOYSA-N

安全信息

象形图GHS07GHS08GHS09
警示用语:Danger
危险声明H302 - H370 - H373 - H411
预防措施声明P260 - P264 - P270 - P273 - P301 + P312 - P308 + P311
危险分类Acute Tox. 4 Oral - Aquatic Chronic 2 - STOT RE 2 - STOT SE 1
靶器官Blood
储存分类代码6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGKWGK 1
闪点(F)Not applicable
闪点(C)Not applicable
D0100000DapsoneEuropean Pharmacopoeia (EP) Reference Standard1277.32元/ ;   展开

产品说明

一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

包装

Unit quantity: 100 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

注意

Please find SDS provided by EDQM here..

其他说明

Sales restrictions may apply.

基本信息

线性分子式(H2NC6H4)2SO2
分子量248.30
Beilstein788055
MDL编号MFCD00007887
PubChem化学物质编号329798581
NACRESNA.24

产品性质

等级pharmaceutical primary standard
agencyEP Reference Standard
manufacturer/tradenameEDQM
mp175-177 ℃ (lit.)
application(s)pharmaceutical (small molecule)
格式neat
储存温度2-8℃
SMILES stringNc1ccc(cc1)S(=O)(=O)c2ccc(N)cc2
InChI1S/C12H12N2O2S/c13-9-1-5-11(6-2-9)17(15,16)12-7-3-10(14)4-8-12/h1-8H,13-14H2
InChI keyMQJKPEGWNLWLTK-UHFFFAOYSA-N

安全信息

象形图GHS07GHS08GHS09
警示用语:Danger
危险声明H302 - H370 - H373 - H411
预防措施声明P260 - P264 - P270 - P273 - P301 + P312 - P308 + P311
危险分类Acute Tox. 4 Oral - Aquatic Chronic 2 - STOT RE 2 - STOT SE 1
靶器官Blood
储存分类代码6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGKWGK 1
A74807Sigma-Aldrich4-Aminophenyl sulfone97%489.86元/100 G;   1649.52元/500 G;   展开

产品说明

一般描述

4-氨基苯砜(DDS)是一种用于固化环氧树脂的二胺类固化剂。

应用

四官能环氧树脂可以与DDS混合,并且可以加热固化,用于油田应用。DDS也可用于固化氧化铁 (Fe2O3) 层状双氢氧化物基环氧树脂,形成阻燃环氧树脂纳米复合材料。它还可用作固化剂,固化用于制造阻燃环氧树脂/黏土纳米复合材料的双酚A (DGEBA)。

包装

100, 500 g in poly bottle

基本信息

线性分子式(H2NC6H4)2SO2
分子量248.30
Beilstein788055
EC 号201-248-4
MDL编号MFCD00007887
PubChem化学物质编号24891242

产品性质

质量水平200
测定97%
mp175-177 ℃ (lit.)
SMILES stringNc1ccc(cc1)S(=O)(=O)c2ccc(N)cc2
InChI1S/C12H12N2O2S/c13-9-1-5-11(6-2-9)17(15,16)12-7-3-10(14)4-8-12/h1-8H,13-14H2
InChI keyMQJKPEGWNLWLTK-UHFFFAOYSA-N

安全信息

象形图GHS07GHS08GHS09
警示用语:Danger
危险声明H302 - H370 - H373 - H411
预防措施声明P260 - P264 - P270 - P273 - P301 + P312 - P308 + P311
危险分类Acute Tox. 4 Oral - Aquatic Chronic 2 - STOT RE 2 - STOT SE 1
靶器官Blood
储存分类代码6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGKWGK 1
个人防护装备dust mask type N95 (US), Eyeshields, Gloves
8.21073Sigma-Aldrich4,4′-Diaminodiphenyl sulfonefor synthesis225.62元/5 G;   375.51元/250 G;   展开

产品说明

分析说明

Assay (HPLC, area%): ≥ 97.0 % (a/a)
Melting range (lower value): ≥ 175 °C
Melting range (upper value): ≤ 180 °C
Identity (IR): passes test

基本信息

线性分子式[4-(NH2)C6H4]2SO2
分子量248.30
MDL编号MFCD00007887
EC索引号201-248-4

产品性质

质量水平200
测定≥97.0% (HPLC)
效能1000 mg/kg LD50, oral (Rat)
>4000 mg/kg LD50, skin (Rabbit)
pH值(酸碱度)5.5-7.5 (20 ℃ in H2O, saturated aqueous solution)
mp172-175 ℃
溶解性 0.38 g/L
堆积密度250‑350 kg/m3
储存温度2-30℃
InChI1S/C12H12N2O2S/c13-9-1-5-11(6-2-9)17(15,16)12-7-3-10(14)4-8-12/h1-8H,13-14H2
InChI keyMQJKPEGWNLWLTK-UHFFFAOYSA-N

安全信息

象形图GHS07GHS08GHS09
警示用语:Danger
危险声明H302 - H370 - H373 - H411
预防措施声明P260 - P264 - P270 - P273 - P301 + P312 - P308 + P311
危险分类Acute Tox. 4 Oral - Aquatic Chronic 2 - STOT RE 2 - STOT SE 1
靶器官Blood
储存分类代码6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGKWGK 1
BP102DapsoneBritish Pharmacopoeia (BP) Reference Standard1861.35元/100 MG;   展开

产品说明

一般描述

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

包装

Unit quantity: 100 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity please visit British Pharmacopoeia

其他说明

Sales restrictions may apply.

基本信息

线性分子式(H2NC6H4)2SO2
分子量248.30
Beilstein788055
EC 号201-248-4
MDL编号MFCD00007887
NACRESNA.24

产品性质

等级pharmaceutical primary standard
manufacturer/tradenameBP
mp175-177 ℃ (lit.)
格式neat
储存温度2-8℃
SMILES stringNc1ccc(cc1)S(=O)(=O)c2ccc(N)cc2
InChI1S/C12H12N2O2S/c13-9-1-5-11(6-2-9)17(15,16)12-7-3-10(14)4-8-12/h1-8H,13-14H2
InChI keyMQJKPEGWNLWLTK-UHFFFAOYSA-N

安全信息

象形图GHS07GHS08GHS09
警示用语:Danger
危险声明H302 - H370 - H373 - H411
预防措施声明P260 - P264 - P270 - P273 - P301 + P312 - P308 + P311
危险分类Acute Tox. 4 Oral - Aquatic Chronic 2 - STOT RE 2 - STOT SE 1
靶器官Blood
储存分类代码6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGKWGK 1
358228Fluorochem4-[(4-aminobenzene)sulfonyl]aniline97%220元/1g;   396元/25g;   726元/100g;   1672元/500g;   展开

基本信息

CAS Number80-08-0
MDL NumberMFCD00007887
Melting Point173-181℃

安全信息

图形或危害标志
危险性说明 H302: Harmful if swallowed.
H371: May cause damage to organs ..
H373: May cause damage to organs ..
H411: Toxic to aquatic life with long lasting effects.
防范说明 P260: Do not breathe .
P264: Wash hands thoroughly after handling.
P270: Do not eat, drink or smoke when using this product.
P273: Avoid release to the environment.
P301 + P312: IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell.
P309: IF exposed or if you feel unwell: .
P309 + P311: IF exposed or if you feel unwell: Call a POISON CENTER or doctor/physician.
P311: Call a POISON CENTER or doctor/physician.
P314: Get medical advice/attention if you feel unwell.
P330: Rinse mouth.
P391: Collect spillage.
P405: Store locked up.
P501: Dispose of contents/container to local regulations.
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